GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2

CAS No.
Chemical Name:
GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2
Synonyms
AKH;LOM II;AKH (LOCUST);PYR-LNFTPNWGT-NH2;ADIPOKINETIC HORMONE;ADIPOKINETIC HORMONE (LOCUST);ADIPOKINETIC HORMONE AKH LOCUST;AKH, Adipokinetic Hormone, Lom II;GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2;PYR-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2
CBNumber:
CB0314073
Molecular Formula:
C54H74N14O15
Molecular Weight:
1159.25
MDL Number:
MFCD00080027
MOL File:
Mol file

GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J66880 Adipokinetic Hormone, locust 1mg $64.7 2021-12-16 Buy
American Custom Chemicals Corporation PEP0000383 ADIPOKINETIC HORMONE (AKH), LOCUST 95.00% 1MG $1164.24 2021-12-16 Buy
Product number Packaging Price Buy
J66880 1mg $64.7 Buy
PEP0000383 1MG $1164.24 Buy

GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2 Chemical Properties,Uses,Production

Description

Adipokinetic hormone (AKH) mobilizes carbohydrates and lipids from storage into the hemolymph for energy demands such as a long flight. Thus, AKH is a functional counterpart of vertebrate glucagon. The red pigment concentrating hormone (RPCH), structurally related to AKH, controls the granule of the crustacean chromatophore, eventually changing the body color.

Structure

AKH has been identified in more than 40 insect species so far.In most insect species, several AKH subtypes are present. In L. migratoria, two structurally related subtypes (AKH-II and -III) have been identified.Some AKH subtypes are exceptionally nonapeptides and decapeptides. The number of subtypes differs according to species. No subtypes of crustacean RPCH are known.

Biological functions

AKH stimulates the fat body, where lipids and carbohydrates are stored, eventually resulting in lipid and carbohydrate mobilization into the hemolymph. The increase in hemolymph lipids is accompanied by the activation of the lipid transfer system. According to the effects of the increase in hemolymph carbohydrates and lipids, locomotor and flight muscles are concomitantly activated.AKH is also required for proper food digestion, enhancing the protease and amylase activities in the midgut of Sarcophaga crassipalpis and Periplaneta americana, respectively.RPCH, however, influences the concentration of the pigment chromatophore, causing drastic body color changes in the crustacean species.

Regulation of synthesis and release

AKH is released from the secretary granule in the CC. AKH secretion is modulated by nutritional status, including the need for extra loading of lipids and carbohydrates for long migratory flights.In a recent study, a glucosesensing neuron pair was identified as regulating AKH release in Drosophila.AKH is released from the CC by a high concentration of potassium in vitro.

GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2 Suppliers

Global( 42)Suppliers
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Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Hangzhou Peptide Biochem Co.,Ltd 0571-89197072; 18668118770 linda@peptide-china.com China 248 56
Nanjing Leon Biological Technology Co., Ltd. 17705183659 sales@njleonbiotech.com China 5504 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 13082558573 liugang@njpeptide.com China 9960 55
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 eric@peptidego.com China 6119 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19105 58
Hangzhou Xinhai Pharmaceutical Technology Co., Ltd. 0571-86758863 13867485072 lulu@thinheal.com China 300 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14092 58
GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2: GLP-LNFTPNWGT-NH2 AKH, Adipokinetic Hormone, Lom II PYR-LNFTPNWGT-NH2 PYR-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2 GLP-LEU-ASN-PHE-THR-PRO-ASN-TRP-GLY-THR-NH2 LOM II AKH AKH (LOCUST) ADIPOKINETIC HORMONE ADIPOKINETIC HORMONE AKH LOCUST ADIPOKINETIC HORMONE (LOCUST) C54H74N14O15 Peptide