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BOC-L-Tyrosine

BOC-L-Tyrosine Structure
BOC-L-Tyrosine structure
CAS No.
3978-80-1
Chemical Name:
BOC-L-Tyrosine
Synonyms
BOC-TYR-OH;Boc-Tyr;(tert-butoxycarbonyl)-L-tyrosine;BOC-L-TYR-OH;N-BOC-L-TYROSINE;(2S)-3-(4-Hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate;TYRO-006;BOC-TYROSINE;BOC-L-TYROSINE;Boc-Tyr-OH 98%
CBNumber:
CB0314497
Molecular Formula:
C14H19NO5
Molecular Weight:
281.3
MDL Number:
MFCD00037179
MOL File:
3978-80-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:37
Product description Number Pack Size Price
Boc-Tyr-OH Novabiochem? 8.53043 25g $185
Boc-Tyr-OH Novabiochem? 8.53043 100g $571
Boc-Tyr-OH 98% 374229 5g $88.6
N-(tert-Butoxycarbonyl)-L-tyrosine >98.0%(HPLC)(T) B1640 5g $28
N-(tert-Butoxycarbonyl)-L-tyrosine >98.0%(HPLC)(T) B1640 25g $105
More product size
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BOC-L-Tyrosine Properties

Melting point 133-135 °C(lit.)
alpha 2.5 º (c=2, acetic acid)
Boiling point 423.97°C (rough estimate)
Density 1.1755 (rough estimate)
refractive index 1.5230 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Sparingly)
form Powder
pka 2.98±0.10(Predicted)
color White to off-white
optical activity [α]20/D +3.0°, c = 2 in acetic acid
BRN 2816406
Major Application peptide synthesis
InChI InChI=1S/C14H19NO5/c1-14(2,3)20-13(19)15-11(12(17)18)8-9-4-6-10(16)7-5-9/h4-7,11,16H,8H2,1-3H3,(H,15,19)(H,17,18)/t11-/m0/s1
InChIKey CNBUSIJNWNXLQQ-NSHDSACASA-N
SMILES C(O)(=O)[C@H](CC1=CC=C(O)C=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference 3978-80-1(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
HS Code  29242990
Storage Class 11 - Combustible Solids
NFPA 704
0
0 0

BOC-L-Tyrosine price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.53043 Boc-Tyr-OH Novabiochem? 3978-80-1 25g $185 2026-04-30 Buy
Sigma-Aldrich 8.53043 Boc-Tyr-OH Novabiochem? 3978-80-1 100g $571 2026-04-30 Buy
Sigma-Aldrich 374229 Boc-Tyr-OH 98% 3978-80-1 5g $88.6 2026-04-30 Buy
TCI Chemical B1640 N-(tert-Butoxycarbonyl)-L-tyrosine >98.0%(HPLC)(T) 3978-80-1 5g $28 2026-04-30 Buy
TCI Chemical B1640 N-(tert-Butoxycarbonyl)-L-tyrosine >98.0%(HPLC)(T) 3978-80-1 25g $105 2026-04-30 Buy
Product number Packaging Price Buy
8.53043 25g $185 Buy
8.53043 100g $571 Buy
374229 5g $88.6 Buy
B1640 5g $28 Buy
B1640 25g $105 Buy

BOC-L-Tyrosine Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

N-Boc-L-tyrosine is an N-Boc-protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

In a dry 50 mL round-bottomed flask, (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid ( 200 mg) was dissolved in dry 1,4 -dioxane ( 10 mL) and H2O (5 mL) ( 2:1 ). NaOH ( 1 M, 5 mL, 5 mmol, 4.5 eq.) and Boc2O ( 0.28 mL, 1.21 mmol) were then added sequentially to the solution. The resulting reaction mixture was stirred at room temperature for 3 h. The progress of the reaction was monitored by LCMS and after waiting for the end of the reaction the reaction solution was acidified with 2 M HCl to a pH of about 2 - 3. The resulting reaction mixture was extracted three times with ethyl acetate ( 3 25 mL), all the organic layers were combined and the organic layer was washed with brine, the organic layer was separated out and dried with anhydrous Na2SO4, the organic layer was filtered to remove the drying agent, and the resulting organic layer was dried with anhydrous Na2SO4. The organic layer was separated and dried with anhydrous Na2SO4, the organic layer was filtered to remove the desiccant, and the resulting filtrate was concentrated under vacuum to remove the organic solvent, and the crude product was separated and purified by silica gel column chromatography to obtain the target product molecule, N-tert-butoxycarbonyl-L-tyrosine.

BOC-L-Tyrosine synthesis

60-18-4
3978-80-1
Synthesis of BOC-L-Tyrosine from L-Tyrosine

BOC-L-Tyrosine Preparation Products And Raw materials

Raw materials

Boc-O-benzyl-L-tyrosine BOC-L-TYR(ALL)-OH BOC-TYR-OBZL Boc-Tyr-OtBu Boc-O-(2-bromo-Cbz)-L-Tyrosine
TERT-BUTYL 1,2,2,2-TETRACHLOROETHYL CARBONATE) L-Tyrosine Di-tert-butyl dicarbonate BOC-TYR(2,6-DI-CL-BZL)-OH

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Preparation Products

2-Pyridinethione 2-Hydroxypyridine

BOC-L-Tyrosine Suppliers

Global( 409)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		+8618382028708 ni@enlaibio.com China 1100 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
AB PharmaTech,LLC 		323-480-4688 sales@acrospharmatech.com United States 989 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29817 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Supplier Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
AB PharmaTech,LLC 		55
career henan chemical co 		58
Xiamen AmoyChem Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
SIMAGCHEM CORP 		58

View Lastest Price from BOC-L-Tyrosine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Tyr-OH pictures 2026-05-15 Boc-Tyr-OH
3978-80-1
 US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
Boc-L-Tyr-OH pictures 2026-05-14 Boc-L-Tyr-OH
3978-80-1
 US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
BOC-L-Tyrosine pictures 2025-05-23 BOC-L-Tyrosine
3978-80-1
 US $50.00 / kg 1kg 99 5000 Hebei Zhuanglai Chemical Trading Co Ltd
  • Boc-Tyr-OH pictures
  • Boc-Tyr-OH
    3978-80-1
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Boc-L-Tyr-OH pictures
  • Boc-L-Tyr-OH
    3978-80-1
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • BOC-L-Tyrosine pictures
  • BOC-L-Tyrosine
    3978-80-1
  • US $50.00 / kg
  • 99
  • Hebei Zhuanglai Chemical Trading Co Ltd

BOC-L-Tyrosine Spectrum

BOC-L-Tyrosine(3978-80-1)MSBOC-L-Tyrosine(3978-80-1)1HNMRBOC-L-Tyrosine(3978-80-1)13CNMRBOC-L-Tyrosine(3978-80-1)IR1BOC-L-Tyrosine(3978-80-1)IR2BOC-L-Tyrosine(3978-80-1)Raman

3978-80-1(BOC-L-Tyrosine)Related Search:

N-[(tert-Butoxy)carbonyl]-L-tryptophan Boc-Aib-OH N-BOC-1,6-diaminohexane BOC-METYR(ME)-OH DCHA N-Boc-Ethylenediamine
BOC-L-TYROSINE(2-BROMOCBZ) Boc-O-benzyl-L-tyrosine BOC-TYR(2,6-DI-CL-BZL)-OH Boc-Tyr(Me)-OH BOC-L-Tyrosine
BOC-TYR(ET)-OH N-tert-Butyloxycarbonyl-N-methyl-O-benzyl-L-threonine Boc-L-tyrosine methyl ester, N-(tert-Butoxycarbonyl)-L-tyrosine methyl ester,BOC-L-TYROSINE METHYL ESTER,N-BOC-L-TYROSINE METHYL ESTER Boc-D-Tyr-OH BOC-D-TYROSINE(2-BROMO-Z)-OH
BOC-L-TYROSINE ETHYL ESTER BOC-D-TYROSINE(BZL)-OH BOC-D-TYROSINE(ET)-OH

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BOC-L-Tyrosine, 99+% 5GR N-Boc-L-tyrosine Boc-Tyr-OH Boc-Tyr-OH 98% BOC-TYROSINE BOC-TYROSINE-OH BOC-L-PHE(4-OH)-OH BOC-L-TYROSINE BOC-L-TYROSINE-OH Boc-L-tyrosine≥ 98% (HPLC) L-TYROSINE, N-[(1,1-DIMETHYLETHOXY)CARBONYL]- N-tert-Butoxycarbonyl-L-tyrosine, 98+% N-Boc-L-tyrosine,98+% BOC-L-Tyrosine, 99+% tert-butoxycarbonyl-tyrosine N-ALPHA-T-BUTYLOXYCARBONYL-L-TYROSINE (S)-2-(tert-Butoxycarbonylamino)-3-(4-hydroxyphenyl)propanoic acid (S)-2-[(tert-Butyloxycarbonyl)amino]-3-(4-hydroxyphenyl)propionic acid (S)-3-(4-Hydroxyphenyl)-2-(tert-butoxycarbonylamino)propionic acid N-(tert-Butyloxycarbonyl)-L-tyrosine N-[(tert-Butyloxy)carbonyl]-L-tyrosine BOC-L-TYROSINE extrapure N-(tert-Butoxycarbonyl)-L-tyrosine, Boc-L-tyrosine (S)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-HYDROXY-PHENYL)-PROPIONIC ACID N-T-BUTOXYCARBONYL-L-TYROSINE N-(TERT-BUTOXYCARBONYL)-L-TYROSINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-TYROSINE N-ALPHA-T-BUTOXYCARBONYL-L-TYROSINE N-ALPHA-T-BOC-L-TYROSINE (Tert-Butoxy)Carbonyl Tyr-OH TYRO-006 N-(tert-Butyloxycarbonyl)-L-tyrosin (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoic acid 3-(4-hydroxyphenyl)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoate N-(tert-Butoxycarbonyl)-L-tyrosine > BOC-L-Tyrosine USP/EP/BP (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid BOC-TYR-OH BOC-L-TYR-OH (2S)-3-(4-Hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate N-BOC-L-TYROSINE Boc-Tyr (tert-butoxycarbonyl)-L-tyrosine (2S)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbo N-tert-Boc-L-tyrosine Roxatidine Monomer N-Boc-L-tyrosine, 95% 3978-80-1 4HOC6H4CH2CHCOOHNHCOOCCH33 Peptide Synthesis Specialty Synthesis Tyrosine Amino Acid Derivatives Amino Acids (N-Protected) Protected & Labeled Amino Acids Boc-Amino Acids Tyrosine [Tyr, Y] Boc-Amino Acids and Derivative Amino Acids (N-Protected)