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Cetrorelix acetate

CAS No.
120287-85-6
Chemical Name:
Cetrorelix acetate
Synonyms
CETRORELIX;Cetrorelixum;Unii-oon1hfz4ba;CETRORELIX ACID;Cetrorelix acetate;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Cetrorelix?Acetate impurity;Cetrorelix acetate USP/EP/BP;Cetrorelix(Cetrorelix acetate)
CBNumber:
CB0316370
Molecular Formula:
C70H92ClN17O14
Molecular Weight:
1431.04
MDL Number:
MFCD00884467
MOL File:
120287-85-6.mol
MSDS File:
SDS
Last updated:2024-04-18 11:58:16

Cetrorelix acetate Properties

Melting point >259°C (dec.)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly, Heated), Methanol (Very Slightly)
form Solid
pka 9.82±0.15(Predicted)
color White to Off-White
InChIKey SBNPWPIBESPSIF-MHWMIDJBSA-N
FDA UNII OON1HFZ4BA

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360

Cetrorelix acetate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 3536 Cetrorelix acetate 120287-85-6 1 $224 2021-12-16 Buy
Usbiological 163043 Cetrorelix Acetate 120287-85-6 5mg $375 2021-12-16 Buy
Usbiological 254921 Cetrorelix Acetate 120287-85-6 1mg $480 2021-12-16 Buy
Biorbyt Ltd orb364499 Cetrorelix Acetate > 95% 120287-85-6 1mg $695.3 2021-12-16 Buy
Biorbyt Ltd orb364499 Cetrorelix Acetate > 95% 120287-85-6 5mg $1480.7 2021-12-16 Buy
Product number Packaging Price Buy
3536 1 $224 Buy
163043 5mg $375 Buy
254921 1mg $480 Buy
orb364499 1mg $695.3 Buy
orb364499 5mg $1480.7 Buy

Cetrorelix acetate Chemical Properties,Uses,Production

Description

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Originator

Asta Medica (Germany)

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-t rosyl, N5-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

brand name

Cetrotide (Serono).

Cetrorelix acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 239)Suppliers
Supplier Tel Email Country ProdList Advantage
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49999 58
Henan Tengmao Chemical Technology Co. LTD
+8615238638457 salesvip2@hntmhg.com China 415 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Shanghai Affida new material science and technology center
+undefined15081010295 2691956269@qq.com China 359 58
Shanghai Getian Industrial Co., LTD
+86-15373193816 +86-15373193816 mike@ge-tian.com China 272 58
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55

View Lastest Price from Cetrorelix acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cetrorelix acetate pictures 2024-04-18 Cetrorelix acetate
120287-85-6
US $23.00-19.00 / box 1box 99% 100000box Shanghai Getian Industrial Co., LTD
Cetrorelix acetate pictures 2024-04-12 Cetrorelix acetate
120287-85-6
US $0.00-0.00 / Box 1Box 99 50000KG/month Shanghai Affida new material science and technology center
Cetrorelix pictures 2024-03-08 Cetrorelix
120287-85-6
US $10.00 / kg 1kg 99% 1000kg Nantong Guangyuan Chemicl Co,Ltd
  • Cetrorelix acetate pictures
  • Cetrorelix acetate
    120287-85-6
  • US $0.00-0.00 / Box
  • 99
  • Shanghai Affida new material science and technology center
  • Cetrorelix pictures
  • Cetrorelix
    120287-85-6
  • US $10.00 / kg
  • 99%
  • Nantong Guangyuan Chemicl Co,Ltd

Cetrorelix acetate Spectrum

Cetrorelix acetate CETRORELIX ACID CETRIZINEDIHYDROCHLORIDE N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2 Cetrorelixum Cetrorelixum [inn-latin] Unii-oon1hfz4ba Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 acetate salt D-AlaninaMide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aMinocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl- Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH Cetrorelix?Acetate impurity Cetrorelix acetate USP/EP/BP Cetrorelix(Cetrorelix acetate) Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2 CETRORELIX 120287-85-6 20287-85-6 C70H92ClN17O14 C70H92CIN17O14C2H4O2 Peptide GYL