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(R)-(+)-PROPRANOLOL

(R)-(+)-PROPRANOLOL
(R)-(+)-PROPRANOLOL
CAS No.
13071-11-9
Chemical Name:
(R)-(+)-PROPRANOLOL
Synonyms
AY 20694;ICI 47319;R-PROPANOLOL;d-Anapriline;R-PROPRANOLOL;(+)-Anapriline;(R)-(+)-PROPRANOLOL;R-(+)-PROPANOLOL HCL;d-Propranolol hydrochloride;Dexpropranolol hydrochloride
CBNumber:
CB0327608
Molecular Formula:
C16H21NO2.ClH
Formula Weight:
295.81
MOL File:
13071-11-9.mol

(R)-(+)-PROPRANOLOL Properties

Melting point:
196-198 °C(lit.)
storage temp. 
2-8°C
solubility 
ethanol: 10 mg/mL
BRN 
5780490
CAS DataBase Reference
13071-11-9(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
HS Code  2922 19 00
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

(R)-(+)-PROPRANOLOL price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P0689 (R)-(+)-Propranolol hydrochloride ≥98% (TLC) 13071-11-9 100mg $82.4 2018-11-13 Buy
Sigma-Aldrich P0689 (R)-(+)-Propranolol hydrochloride ≥98% (TLC) 13071-11-9 500mg $329 2018-11-13 Buy
Sigma-Aldrich 8.24472 (R)-(+)-Propanolol hydrochloride for synthesis. CAS 13071-11-9, molar mass 295.81 g/mol., for synthesis 13071-11-9 8244720500 $203 2018-11-23 Buy

(R)-(+)-PROPRANOLOL Chemical Properties,Uses,Production

Chemical Properties

(R)-(+)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride

Uses

less active enantiomer

Uses

The R-enantiomer of Propranolol (P831800). β?Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).

Purification Methods

The hydrochloride is recrystallised from n-PrOH or Me2CO. It is soluble in H2O and EtOH but is insoluble in Et2O, *C6H6 or EtOAc. The racemate has m 163-164o, and the free base recrystallises from cyclohexane with m 96o. [Howe & Shanks Nature 210 1336 1966.] The S-isomer (below) is the physiologically active isomer.

(R)-(+)-PROPRANOLOL Preparation Products And Raw materials

Raw materials

Preparation Products


(R)-(+)-PROPRANOLOL Suppliers

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(R)-(+)-PROPRANOLOL Spectrum


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