ChemicalBook >> CAS DataBase List >>BMS-986205
BMS-986205
- CAS No.
- 1923833-60-6
- Chemical Name:
- BMS-986205
- Synonyms
- Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;Linrodostat(BMS-986205);BMS-986205(Linrodostat);LINRODOSTAT;BMS 986205;BMS986205;(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
- CBNumber:
- CB03339862
- Molecular Formula:
- C24H24ClFN2O
- Molecular Weight:
- 410.91
- MDL Number:
- MFCD31619233
- MOL File:
- 1923833-60-6.mol
Last updated:2024-07-02 08:54:58
Boiling point | 606.8±45.0 °C(Predicted) |
---|---|
Density | 1?+-.0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility |
DMSO:42.0(Max Conc. mg/mL);73.75(Max Conc. mM) Ethanol:100.0(Max Conc. mg/mL);175.59(Max Conc. mM) |
form | Solid |
pka | 13.80±0.70(Predicted) |
color | White to off-white |
FDA UNII | 0A7729F42K |
NCI Drug Dictionary | linrodostat |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
BMS-986205 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B596415 | BMS-986205 | 1923833-60-6 | 10mg | $1890 | 2021-12-16 | Buy |
Biosynth Carbosynth | BB165429 | BMS 986205 | 1923833-60-6 | 50mg | $507.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | BB165429 | BMS 986205 | 1923833-60-6 | 10mg | $145 | 2021-12-16 | Buy |
ChemScene | CS-0021719 | Linrodostat 99.92% | 1923833-60-6 | 5mg | $156 | 2021-12-16 | Buy |
ChemScene | CS-0021719 | Linrodostat 99.92% | 1923833-60-6 | 10mg | $288 | 2021-12-16 | Buy |
BMS-986205 Chemical Properties,Uses,Production
Description
BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.
Biological Activity
Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.
Uses
BMS-986205 is a compound being studied for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders.
BMS-986205 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 99)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Hangzhou Proserre Chemical Co.,Ltd. | +86-571-86088112 | info@proserre.com | China | 1077 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
View Lastest Price from BMS-986205 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-02-19 | BMS-986205
1923833-60-6
|
US $0.00 / gram | 1gram | 99% | 10kg | Zhejiang J&C Biological Technology Co.,Limited |
- BMS-986205
1923833-60-6
- US $0.00 / gram
- 99%
- Zhejiang J&C Biological Technology Co.,Limited
1923833-60-6(BMS-986205)Related Search:
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1of4
BMS-986205
LINRODOSTAT;BMS 986205;BMS986205
BMS 986205;BMS986205
BMS-986205(Linrodostat)
CS-2743
(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)-
Linrodostat
(R)-N-(4-Chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
Linrodostat(BMS-986205)
cis-(αR)-N-(4-Chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methylcyclohexaneacetamide
cis-(alphaR)-N-(4-Chlorophenyl)-4-(6-fluoro-quinolin-4-yl)-alpha-methylcyclohexaneacetamide
F001287
F-001287
1923833-60-6
923833-60-6
C24H24ClFN2O
API