ChemicalBook >> CAS DataBase List >>BMS-955829
BMS-955829
- CAS No.
- 1375751-08-8
- Chemical Name:
- BMS-955829
- Synonyms
- BMS-955829;(4R,5R)-5-(2,5-DIFLUOROPHENYL)-4-(5-(PHENYLETHYNYL)PYRIDIN-3-YL)OXAZOLIDIN-2-ONE;2-Oxazolidinone, 5-(2,5-difluorophenyl)-4-[5-(2-phenylethynyl)-3-pyridinyl]-, (4R,5R)-
- CBNumber:
- CB03344769
- Molecular Formula:
- C22H14F2N2O2
- Molecular Weight:
- 376.36
- MDL Number:
- MFCD30471079
- MOL File:
- 1375751-08-8.mol
Last updated:2023-03-31 09:12:58
BMS-955829 Chemical Properties,Uses,Production
Description
BMS-955829 is a Positive allosteric modulators (PAMs). BMS-955829 shows high functional PAM potency, excellent mGluR5 binding affinity, low glutamate fold shift, and high selectivity for the mGluR5 subtype. BMS-955829 is a potent mGluR5 PAM (EC50 = 2.6 ± 1.0 nM; n = 6), devoid of inherent mGluR5 agonist activity (EC50 > 30μM). The measured binding Ki of BMS-955829 was found to be 1.6 nM, which was in good agreement with its functional potency.
BMS-955829 Preparation Products And Raw materials
Raw materials
Preparation Products
BMS-955829 Suppliers
Global( 3)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 16377 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
BMS-955829
(4R,5R)-5-(2,5-DIFLUOROPHENYL)-4-(5-(PHENYLETHYNYL)PYRIDIN-3-YL)OXAZOLIDIN-2-ONE
2-Oxazolidinone, 5-(2,5-difluorophenyl)-4-[5-(2-phenylethynyl)-3-pyridinyl]-, (4R,5R)-
1375751-08-8