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ANGIOTENSIN II, HUMAN

ANGIOTENSIN II, HUMAN
ANGIOTENSIN II, HUMAN structure
CAS No.
4474-91-3
Chemical Name:
ANGIOTENSIN II, HUMAN
Synonyms
Ang II;DRVYIHPF;TY-10721;ANGIOTENSIN-2;ANGIOTENSIN II;angiotensin renin;ANTI-ANGIOTENSIN II;ile(5)-angiotensini;angiotensinii(mouse);[ILE5]-ANGIOTENSIN 2
CBNumber:
CB0338057
Molecular Formula:
C50H71N13O12
Formula Weight:
1046.18
MOL File:
4474-91-3.mol

ANGIOTENSIN II, HUMAN Properties

Boiling point:
809.08°C (rough estimate)
Density 
1.1257 (rough estimate)
refractive index 
1.6700 (estimate)
RTECS 
BW2165000
storage temp. 
−20°C
form 
Powder
pka
pK1: 10.37 (25°C)
color 
orange
Water Solubility 
Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
InChIKey
CZGUSIXMZVURDU-JZXHSEFVSA-N

SAFETY

WGK Germany  3

ANGIOTENSIN II, HUMAN price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 1mg $28.6 2018-11-13 Buy
Sigma-Aldrich A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 5x1mg $112 2018-11-13 Buy
Alfa Aesar J60866 Angiotensin II (human) 4474-91-3 5mg $79.2 2018-11-13 Buy
Alfa Aesar J60866 Angiotensin II (human) 4474-91-3 25mg $290 2018-11-13 Buy
Cayman Chemical 17150 Angiotensin II (human) ≥90% 4474-91-3 1mg $19 2018-11-13 Buy

ANGIOTENSIN II, HUMAN Chemical Properties,Uses,Production

Description

It is known that tumor tissues including metastatic lymph nodes are composed of newly growing vessels which lack blood flow autoregulation and are influenced only secondarily by the responding somatic vessels. Human angiotensin II (AT II). a vasopressor, was introduced in Japan to improve the efficacy of systemic chemotherapy. In patients with various advanced cancers, i.v. infusion of AT II to achieve a mean blood pressure of 1.5 times of baseline (but not over 150 mm Hg) followed by a bolus injection of conventional cytotoxic agents increases blood flow 5-7 fold in tumor tissues and therefore, increases drug delivery to the target tissue resulting in enhanced chemotherapeutic effects. This induced-hypertension chemotherapy regimen can be performed safely with minimal side effects.

Originator

Toa Eiyo (Japan)

Uses

Cardiopulmonary resuscitation - not yet an approved application

Uses

A peptide involved in the regulation of blood pressure

Uses

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two distinct receptors, AT1 and AT2, each evoking distinct signaling pathways and physiological responses. The development of antagonists for specific angiotensin II receptor subtypes represents a valuable alternative to ACE inhibitors.

brand name

Delivert

ANGIOTENSIN II, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products


ANGIOTENSIN II, HUMAN Suppliers

Global( 115)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Rixing Chemical CO.,LTD
13237129059
- info@rixingchemi.com CHINA 235 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
Beijing NuoqiYa Biotechnology Co., Ltd. 4000-819-385 010-62329685 13718666987
010-62340519 good@nuoqiya.com China 1978 55
Creative Peptides
info@creative-peptides.com United States 6295 56
Beijing Solarbio Science & Tecnology Co., Ltd. 010-56371205 56371220
010-56371282 solarbio@163.com China 13805 68
MedChemexpress LLC 609-228-6898
609-228-5909 sales@medchemexpress.com United States 4618 58
Beijing OKA biological technology co., LTD 010-62971590; 62971690; 13718666987
010-62971690 1534154405@qq.com China 10020 58
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85525605
0731-85525605 hbs5505@hnhbsbio.com China 1456 62

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