ChemicalBook >> CAS DataBase List >>BAM-22P

BAM-22P

CAS No.
76622-26-9
Chemical Name:
BAM-22P
Synonyms
BAM22;ADTB1;AP1B1;AP105A;BAM-22P;Peptide E(1-22);BAM 22P acetate;YGGFMRRVGRPEWWMDYQKRYG;BOVINE ADRENAL MEDULLA-22P;BOVINE ADRENAL MEDULLA DOCOSAPEPTIDE
CBNumber:
CB0345600
Molecular Formula:
C130H184N38O31S2
Molecular Weight:
2839.22
MDL Number:
MFCD00076690
MOL File:
76622-26-9.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:20

BAM-22P Properties

Density 1.50±0.1 g/cm3(Predicted)
RTECS SC6200500
storage temp. -15°C
solubility Soluble to 1 mg/ml in H2O
form Lyophilized solid
Water Solubility Soluble to 1 mg/ml in water

BAM-22P price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J66217 BAM-22P 76622-26-9 1mg $254 2021-12-16 Buy
Usbiological B2583 Bovine Adrenal Medulla 22P 76622-26-9 1mg $531 2021-12-16 Buy
Biosynth Carbosynth FB73216 BAM-22P 76622-26-9 2mg $561 2021-12-16 Buy
Biosynth Carbosynth FB108610 BAM-22P H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH 76622-26-9 2mg $680 2021-12-16 Buy
American Custom Chemicals Corporation PEP0000644 BAM-22P 95.00% 76622-26-9 1MG $745.72 2021-12-16 Buy
Product number Packaging Price Buy
J66217 1mg $254 Buy
B2583 1mg $531 Buy
FB73216 2mg $561 Buy
FB108610 2mg $680 Buy
PEP0000644 1MG $745.72 Buy

BAM-22P Chemical Properties,Uses,Production

Biological Activity

bovine adrenal medulla 22 peptide (bam22p) is a peptide with 22 amino acids which is one of the cleavage products of proenkephalin a, the precursor of leu- and met-enkephalin, in the adrenal medulla, with very potent opiate activity.

in vitro

in the guinea-pig ileum assay, bam-22p has been shown to have typical and extraordinarily potent opioid activities antagonized by naloxone. the potency of bam-22p is 26 times that of met-enkephalin and 22 times that of b hendorphin. ic50 value of bam-22p in this tissue, 1.3 nm, makes it the most potent met-enkephalin relatives that discoveried so far. [1].

in vivo

intrathecal (i.t.) administration of bam22 decreased nocifensive behavior scores, which measured as the sum of flinching and lifting/licking, in the first and second phases of the formalin test. such decrease was partially attenuated by systemic injection of naloxone. [2].

target

Opioid receptor

IC 50

1.3 nm for opiate activity

References

[1] mizuno k, minamino n, kangawa k, matsuo h. a new family of endogenous "big" met-enkephalins from bovine adrenal medulla: purification and structure of docosa- (bam-22p) and eicosapeptide (bam-20p) with very potent opiate activity. biochem biophys res commun. 1980 dec 31;97(4):1283-90.
[2] hong y, dai p, jiang j, zeng x. dual effects of intrathecal bam22 on nociceptive responses in acute and persistent pain--potential function of a novel receptor. br j pharmacol. 2004 feb;141(3):423-30.

BAM-22P Preparation Products And Raw materials

Raw materials

Preparation Products

BAM-22P Suppliers

Global( 84)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14770 58
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30256 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY YGGFMRRVGRPEWWMDYQKRYG BAM22 L-Tyr-Gly-Gly-L-Phe-L-Met-L-Arg-L-Arg-L-Val-Gly-L-Arg-L-Pro-L-Glu-L-Trp-L-Trp-L-Met-L-Asp-L-Tyr-L-Gln-L-Lys-L-Arg-L-Tyr-Gly-OH Peptide E(1-22) ADTB1 AP105A AP1B1 BAM-22P BOVINE ADRENAL MEDULLA-22P BOVINE ADRENAL MEDULLA DOCOSAPEPTIDE H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY-ARG-PRO-GLU-TRP-TRP-MET-ASP-TYR-GLN-LYS-ARG-TYR-GLY-OH BAM-22P H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH Glycine, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valylglycyl-L-arginyl-L-prolyl-L-α-glutamyl-L-tryptophyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-arginyl-L-tyrosyl- BAM 22P acetate 76622-26-9 C130H184N38O31S2 Peptide Various Peptides