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4-NITROBENZHYDRAZIDE

CAS No.
636-97-5
Chemical Name:
4-NITROBENZHYDRAZIDE
Synonyms
Inhd18;Nsc 9804;AKOS B016226;AKOS BBS-00001033;P-NITROBENZHYDRAZIDE;4-NITROBENZHYDRAZIDE;P-NITROBENZOHYDRAZIDE;4-NITROBENZOHYDRAZIDE;4-Nireobenzoylhydrazine;p-Nitrobenzoylhydrazide
CBNumber:
CB0355890
Molecular Formula:
C7H7N3O3
Molecular Weight:
181.15
MDL Number:
MFCD00007604
MOL File:
636-97-5.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

4-NITROBENZHYDRAZIDE Properties

Melting point 210-214 °C
Boiling point 292.97°C (rough estimate)
Density 1.3539 (rough estimate)
refractive index 1.5860 (estimate)
solubility acetone: soluble0.5g/10 mL, clear, yellow
pka 2.77, 11.17(at 25℃)
form crystals
color Yellow
PH Range Colorless (8.2) to yellow (9.5)
λmax 267nm
BRN 519882
Major Application corrosion inhibitor, disinfectant, cosmetics, paints toothpaste, mouthwash, antifungal agent, inhibit fibrosis, antituberculosis agent
CAS DataBase Reference 636-97-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII AZ8HT8UU5S
EPA Substance Registry System 4-Nitrobenzoylhydrazine (636-97-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P304+P340-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-20/21/22
Safety Statements  36/37/39-26-37/39
WGK Germany  3
RTECS  DH5670000
TSCA  Yes
HazardClass  IRRITANT
HS Code  29280000
NFPA 704
1
2 0

4-NITROBENZHYDRAZIDE Chemical Properties,Uses,Production

Synthesis

Dissolve 218 g of p-nitrobenzyl acetate in 500 ml of hot methanol, stir, and slowly add 380 g of 15% sodium hydroxide solution. After the addition was completed, it was placed for 5 minutes, and then poured into ice water to precipitate a precipitate. The filtered precipitate was decolorized with activated carbon in hot water, and recrystallized to give p-nitrobenzoicacidhydrazide 110-121 g .

Chemical Properties

yellow crystalline powder

Uses

4-Nitrobenzoic hydrazide has been used as internal standard in determination of isoniazid in human plasma by LC-MS/MS method.

Definition

ChEBI: A C-nitro compound in which the nitro group is substituted into the 4-position of benzohydrazide.

4-NITROBENZHYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-Nitrobenzoic hydrazide 98% ρ-Nitrobenzoyl hydrazine P-NITROBENZHYDRAZIDE P-NITROBENZOHYDRAZIDE Benzoicacid,4-nitro-,hydrazide p-Nitrobenzoic acid hydrazide p-Nitrobenzoic hydrazide p-nitrobenzoicacidhydrazide p-nitro-benzoicacihydrazide p-Nitrobenzoylhydrazide 4-Nireobenzoylhydrazine 4-Nitrobenzhydrazide, 98+% AKOS BBS-00001033 AKOS B016226 Benzoic acid, 4-nitro-, hydrazide Benzoic acid, p-nitro-, hydrazide 4-nitrobenzen-ecarboxylic Acid Hydrazide Inhd18 Nsc 9804 4-NITROBENZOYL HYDRAZIDE 4-NITRO-BENZOIC ACID HYDRAZIDE 4-NITROBENZOIC HYDRAZIDE 4-NITROBENZOIC HYDRAZINE 4-NITROBENZOHYDRAZIDE 4-NITROBENZENECARBOHYDRAZIDE 4-NITROBENZHYDRAZIDE (4-Nitrobenzoyl)hydrazine (p-Nitrobenzoyl)hydrazine 4-nitro-benzoicacihydrazide 3,5-dihydro-2H-imidazo[1,2-b]pyrazole 636-97-5 O2NC6H4CONHNH2 Building Blocks Carbonyl Compounds Hydrazides Organic Building Blocks Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes Carbonyl Compounds Hydrazides Organic Building Blocks Hydrazide Miscellaneous Nitro