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L-xylose

CAS No.
609-06-3
Chemical Name:
L-xylose
Synonyms
XYLOSE;L-(-)-XYLOSE;(2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal;L-XYL;L-XYLOSE;XYLOSE, L;L-Xylose,99%;laevo-xylose;L-Xylose (9CI);L(-)XYLOSE 99%
CBNumber:
CB0357344
Molecular Formula:
C5H10O5
Molecular Weight:
150.13
MDL Number:
MFCD00151096
MOL File:
609-06-3.mol
Last updated:2023-05-25 18:00:56

L-xylose Properties

Melting point 150-152 °C(lit.)
Boiling point 191.65°C (rough estimate)
Density 1.525
refractive index -20 ° (C=10, H2O)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: 0.1 g/mL, clear, colorless
pka 12.46±0.20(Predicted)
form Crystalline Powder
color White to off-white
optical activity [α]24/D 18.7°, c = 4 in H2O
Water Solubility within almost transparency
Sensitive Hygroscopic
BRN 1723080
InChIKey SRBFZHDQGSBBOR-VVZXFQNISA-N
LogP -2.390 (est)
CAS DataBase Reference 609-06-3(CAS DataBase Reference)
FDA UNII A4JW0V2MYA
EPA Substance Registry System L-Xylose (609-06-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
3-10
TSCA  Yes
HS Code  29400000
NFPA 704
1
1 0

L-xylose price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 851590 L-(?)-Xylose, mixture of anomers ≥99% 609-06-3 5g $29.94 2024-03-01 Buy
Sigma-Aldrich 851590 L-(?)-Xylose, mixture of anomers ≥99% 609-06-3 25g $56.6 2024-03-01 Buy
TCI Chemical X0021 L-(-)-Xylose >97.0%(T) 609-06-3 5g $67 2024-03-01 Buy
TCI Chemical X0021 L-(-)-Xylose >97.0%(T) 609-06-3 25g $267 2024-03-01 Buy
Alfa Aesar B21622 L-(-)-Xylose, 99% 609-06-3 5g $46.65 2024-03-01 Buy
Product number Packaging Price Buy
851590 5g $29.94 Buy
851590 25g $56.6 Buy
X0021 5g $67 Buy
X0021 25g $267 Buy
B21622 5g $46.65 Buy

L-xylose Chemical Properties,Uses,Production

Chemical Properties

L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.
structure of L-xylose
Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form.

Uses

L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Definition

ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.

Application

l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).
L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007).

Preparation

L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).

1195193-89-5
609-06-3
Synthesis of L-xylose from L-Xylose, 2,3,4,5-tetraacetate

L-xylose Preparation Products And Raw materials

Global( 284)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Ribio Biotech Co.,Ltd
010-62664360 +8613328773880 wucy@ribio.com.cn China 117 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14936 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9354 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8136 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58

View Lastest Price from L-xylose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-xylose pictures 2023-01-06 L-xylose
609-06-3
US $0.00-0.00 / KG 1KG 98.0% 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
L-XYLOSE pictures 2022-12-07 L-XYLOSE
609-06-3
US $0.00-0.00 / kg 1kg 98.0%min 10tons/year AstaTech(Chengdu) Biopharmaceutical Corp.
L-XYLOSE pictures 2021-08-12 L-XYLOSE
609-06-3
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • L-xylose pictures
  • L-xylose
    609-06-3
  • US $0.00-0.00 / KG
  • 98.0%
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • L-XYLOSE pictures
  • L-XYLOSE
    609-06-3
  • US $0.00-0.00 / kg
  • 98.0%min
  • AstaTech(Chengdu) Biopharmaceutical Corp.
  • L-XYLOSE pictures
  • L-XYLOSE
    609-06-3
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
aldehydo-L-xylose XYLOSE, L L-(-)-Xylose, 99+%, mixture of anomers L(-)XYLOSE 99% L-Xylose (9CI) L-Xylose,99% l-(-)-xylose, mixture of anomers XYLOSE, L-(RG) L-XYLOSE XYLO-PFAN (xylose) l-[1,2-13C2]xylose l-[UL-13C5]xylose L-(-)-Xylose, Mixture of anoMers >=99% L-(-)-Xylose≥ 98% (TLC) L-(-)-Xylose,L-XYLOSE L-XYLOSE USP/EP/BP laevo-xylose TIANFU-CHEM L-XYLOSE L-(-) Xylose extrapure, 99% L-XYL L-(-)-XYLOSE (2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal XYLOSE L-Xylose (9CI, ACI) 609-06-3 Monosaccharides Microbiology ALDEHYDE Sugars Basic Sugars (Mono & Oligosaccharides) Sugars for Media Specialty Synthesis BioChemical Base Ingredients Carbohydrate Sources (Sugars/Extracts) Carbohydrate Synthesis CARBOHYDRATE Basic Sugars (Mono & Oligosaccharides) Biochemistry Sugars Xylose Carbohydrate Sources (Sugars/Extracts) MonosaccharidesBase Ingredients Sugars for Media Carbohydrate Synthesis Specialty Synthesis Monosaccharides bc0001