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2-Chloro-6-methylaniline

2-Chloro-6-methylaniline Structure
2-Chloro-6-methylaniline structure
CAS No.
87-63-8
Chemical Name:
2-Chloro-6-methylaniline
Synonyms
6-CHLORO-O-TOLUIDINE;6-CHLORO-2-METHYLANILINE;6COT;NSC 60121;oro-6-methyL;TIMTEC-BB SBB004153;6-chloro-o-toluidin;2-Chloro-6-methylani;6-CHLORO-2-TOLUIDINE;6-ChIoro-o-toluidine
CBNumber:
CB0361613
Molecular Formula:
C7H8ClN
Molecular Weight:
141.6
MDL Number:
MFCD00007679
MOL File:
87-63-8.mol
Last updated:2024-02-20 10:02:12
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2-Chloro-6-methylaniline Properties

Melting point 10-12 °C(lit.)
Boiling point 215 °C(lit.)
Density 1.152 g/mL at 25 °C(lit.)
refractive index n20/D 1.576(lit.)
Flash point 210 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Oil
pka 2.51±0.10(Predicted)
color Clear Colourless to Pale Purple
Water Solubility Immiscible
BRN 774624
InChIKey WFNLHDJJZSJARK-UHFFFAOYSA-N
CAS DataBase Reference 87-63-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 76F11RQ7TB
NIST Chemistry Reference Benzenamine, 2-chloro-6-methyl-(87-63-8)
EPA Substance Registry System 6-Chloro-2-methylaniline (87-63-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H311+H331-H341-H373-H410
Precautionary statements  P201-P273-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39
RIDADR  UN 3429 6.1/PG 3
WGK Germany  3
RTECS  XU5100000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29214300
NFPA 704
0
2 0

2-Chloro-6-methylaniline price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C51008 2-Chloro-6-methylaniline 98% 87-63-8 1g $35.4 2023-01-07 Buy
TCI Chemical A1959 2-Chloro-6-methylaniline >98.0%(GC)(T) 87-63-8 5g $70 2024-03-01 Buy
TCI Chemical A1959 2-Chloro-6-methylaniline >98.0%(GC)(T) 87-63-8 25g $205 2024-03-01 Buy
Alfa Aesar L02629 2-Chloro-6-methylaniline, 98% 87-63-8 25g $315.65 2024-03-01 Buy
Alfa Aesar L02629 2-Chloro-6-methylaniline, 98% 87-63-8 1g $37.1 2021-12-16 Buy
Product number Packaging Price Buy
C51008 1g $35.4 Buy
A1959 5g $70 Buy
A1959 25g $205 Buy
L02629 25g $315.65 Buy
L02629 1g $37.1 Buy

2-Chloro-6-methylaniline Chemical Properties,Uses,Production

Description

2-chloro-6-methylaniline is an important organic synthesis intermediate widely applied to chemical pharmacy, pesticides, and organic synthesis. In the aspects of chemical pharmacy and pesticides, 2-chloro-6-methylaniline can be used as a reaction starting material to participate in the preparation processes of tyrosine kinase inhibitors dasatinib, indazole derivatives with anti-breast cancer activity, 2-methyl-6-chlorophenyl sulfonylurea derivatives with bacteriostatic activity and the like; in the aspect of organic synthesis, 2-chloro-6-methylaniline can introduce chemical groups such as hydrazine, nitro, cyano, halogen (F, Cl, Br), and the like into an aromatic ring through diazotization reaction, thereby participating in wide chemical reactions.

Chemical Properties

clear yellow to red-brown liquid

Chemical Properties

The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.

Uses

2-Chloro-6-methylaniline is a substituted aniline used in the preparation of various pharmaceutical compounds. 2-Chloro-6-methylaniline showed inhibition of the polymerization of vinyl acetate.

Preparation

A preparation method of 2-chloro-6-methylaniline takes 3-chloro-5-methyl-4-nitroaniline as a starting material, water as a solvent, and sulfuric acid as a reactant. Eliminates amino groups through diazotization reaction, reduces by hypophosphorous acid to obtain an intermediate, and finally takes iron powder as reducing nitro groups to prepare the 2-chloro-6-methylaniline through a one-pot reaction.

Potential Exposure

Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill birds. It is marketed as pelleted bait for control of bird populations.

Shipping

UN2239 Chlorotoluidines, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3429 Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1- Poisonous materials

Incompatibilities

Incompatible with oxidizers, strong acids; chloroformates, and acid anhydrides, isocyanates, aldehydes forming fire and explosive hazards.

2-Chloro-6-methylaniline Preparation Products And Raw materials

Raw materials

4-Chloro-2-methylaniline

Preparation Products

2-AMINO-3-CHLOROBENZOTRIFLUORIDE 2-CHLORO-6-METHYLBENZALDEHYDE 1H-Pyrazole-3-carboxylic acid, 4-[(2-chloro-6-methylphenyl)azo]-1-(2-chloro-6-methyl-4-sulfophenyl)-4,5-dihydro-5-oxo-, 3-ethyl ester, sodium salt N-(2-CHLORO-6-METHYLPHENYL)FORMAMIDE& 2-Chloro-4-iodo-6-MethylbenzenaMine
2,2'-methylenebis[3-chlorotoluene]

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2-Chloro-6-methylaniline Suppliers

Global( 391)Suppliers
Supplier Tel Email Country ProdList Advantage
China Synchem Technology Co.,Ltd.
+86-0552-4929304 +86-18055277008 wangxuhui1985@126.com China 55 55
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Shanghai Arbor Chemical Co., Ltd. 		021-60451682 act@arborchemical.com CHINA 906 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Supplier Advantage
China Synchem Technology Co.,Ltd.
55
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shanghai Arbor Chemical Co., Ltd. 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Hubei Jusheng Technology Co.,Ltd. 		58

View Lastest Price from 2-Chloro-6-methylaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-6-methylaniline pictures 2024-01-02 2-Chloro-6-methylaniline
87-63-8
 US $50.00-1.00 / KG 1KG 99 g-kg-tons,free sample is available Henan Fengda Chemical Co., Ltd
2-Chloro-6-methylaniline, 98% pictures 2023-02-16 2-Chloro-6-methylaniline, 98%
87-63-8
 US $42.00 / kg 1kg 98% 5000 tons Hebei Duling International Trade Co. LTD
2-Chloro-6-methylaniline pictures 2022-10-01 2-Chloro-6-methylaniline
87-63-8
 US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

2-Chloro-6-methylaniline Spectrum

2-Chloro-6-methylaniline(87-63-8)1HNMR2-Chloro-6-methylaniline(87-63-8)13CNMR2-Chloro-6-methylaniline(87-63-8)IR12-Chloro-6-methylaniline(87-63-8)Raman

87-63-8(2-Chloro-6-methylaniline)Related Search:

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benzenamine,2-chloro-6-methyl- benzenamine,2-chloro-6-methyl-(6-cot) o-Toluidine, 6-chloro- 2-chloro-6-methylbenzenamine 2-Chloro-6-methyl-phenylamine 2-CHLORO-6-METHYLANINILE BENZENEAMINE,2-CHLORO-6-METHYL- 2-Chloro-6-methylaniline, typically 99% 2-Amino-3-chlorotoluene, 6-Chloro-o-toluidine 2-Chloro-6-methylaniline(6-Chloro-o-toluidine) 2-Chloro-6-methylani NSC 60121 6COT 6-CHLORO-2-TOLUIDINE 3-CHLORO-2-AMINOTOLUENE 1-AMINO-2-CHLORO-6-METHYLBENZENE 2-METHYL-6-CHLORO ANILINE 2-AMINO-3-CHLOROTOLUENE 2-CHLORO-6-METHYLANILINE TIMTEC-BB SBB004153 2-chloro-6-methyl-benzenamin 6-ChIoro-o-toluidine 6-chloro-2-methyl-benzenamin 6-chloro-o-toluidin 6-Chloro-o-toluidine (NH2=1) 2-Chloro-6-methylaniline 97% 2-chlro6-methylaniline 2-Chloro-6-methylaniline > 2-Chloro-6-methylanilineSolution,1000mg/L,1ml oro-6-methyL DASATINIB - 2-CHLORO-6-METHYLANILINE Dasatinib Impurity W 87-63-8 2-Chloro-6-methylaniline 6-CHLORO-2-METHYLANILINE 6-CHLORO-O-TOLUIDINE 87-63-8 C7 Amines Building Blocks Nitrogen Compounds Organic Building Blocks benzene derivative Anilines, Aromatic Amines and Nitro Compounds pharmaceutical