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ARG-GLY-ASP

ARG-GLY-ASP structure

CAS No.: 99896-85-2

Chemical Name:: ARG-GLY-ASP

Synonyms: RGD;F-336;H2N-RGD-OH;ARG-GLY-ASP;L-ARG-GLY-ASP;H-ARG-GLY-ASP-OH;RGD (Arg-Gly-Asp);Arg-Gly-Asp (TLC);RGD PEPTIDE (CORE);Arg-Gly-Asp acetate

CBNumber:: CB0364876

Molecular Formula:: C12H22N6O6

Molecular Weight:: 346.34

MDL Number:: MFCD00057952

MOL File:: 99896-85-2.mol

MSDS File:: SDS

Last updated:2023-10-25 16:14:51

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ARG-GLY-ASP Properties

Melting point	153-155℃ (ethyl ether )
Density	1.61±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in 0.1N acetic acid at 20mg/ml
pka	2.85±0.10(Predicted)
form	Powder
Water Solubility	Soluble to 12 mg/mL (34.64 mM) in Water
InChIKey	IYMAXBFPHPZYIK-BQBZGAKWSA-N
FDA UNII	78VO7F77PN

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319
Precautionary statements	P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
WGK Germany	3

ARG-GLY-ASP price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A8052	Arg-Gly-Asp ≥97% (TLC)	99896-85-2	1mg	$34.7	2024-03-01	Buy
Sigma-Aldrich	A8052	Arg-Gly-Asp ≥97% (TLC)	99896-85-2	5mg	$101	2024-03-01	Buy
Alfa Aesar	J65468	Arg-Gly-Asp	99896-85-2	5mg	$164	2023-06-20	Buy
Sigma-Aldrich	A8052	Arg-Gly-Asp ≥97% (TLC)	99896-85-2	10mg	$182	2024-03-01	Buy
Usbiological	260168	Arg-Gly-Asp	99896-85-2	50mg	$305	2021-12-16	Buy

Product number	Packaging	Price	Buy
A8052	1mg	$34.7	Buy
A8052	5mg	$101	Buy
J65468	5mg	$164	Buy
A8052	10mg	$182	Buy
260168	50mg	$305	Buy

ARG-GLY-ASP Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

Arg-Gly-Asp has been used:

to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogel
in adhesion assay
in inhibition assay to confirm the β1-integrin-dependency of cell adhesion
in textile fabrication and RGD textile functionalization
to engineer a population of human dermal fibroblasts with impaired migration
to modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)
in the cell culture of human mammary epithelial cells

Definition

ChEBI: Arg-Gly-Asp is an oligopeptide.

General Description

Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.

Biological Activity

synthetic peptides containing the arginine-glycine-aspartate (rgd) were extensively used as inhibitors of integrin-ligand interactions in studies of cell adhesion, migration, growth and differentiation, since the rgd motif is an integrin-recognition motif found in many ligands.

Biochem/physiol Actions

Primary sequence involved with the binding of proteins to cell surfaces

in vitro

rgd peptide can induce apoptosis in the absence of signals and integrin-mediated cell clustering. previous study demonstrates that rgd peptides promote apoptosis through activation of conformation changes enhancing pro-caspase-3 activation and autoprocessing [1].

in vivo

anima study suggested that the rgd-4c-fitc-peptide bound to both endothelial and tumor cells in vivo and that peptide targeting should allow the delivery of therapeutic drugs to both endothelial and tumor cells [2].

target

integrin-ligand interaction

storage

Store at -20°C

References

[1] nature. 1999 feb 11;397(6719):534-9.rgd peptides induce apoptosis by direct caspase-3 activation. buckley cd1, pilling d, henriquez nv, parsonage g, threlfall k, scheel-toellner d, simmons dl, akbar an, lord jm, salmon m.
[2] cancer res. 2002 sep 15;62(18):5139-43. arginine-glycine-aspartic acid (rgd)-peptide binds to both tumor and tumor-endothelial cells in vivo. zitzmann s1, ehemann v, schwab m.

ARG-GLY-ASP Preparation Products And Raw materials

Raw materials

Preparation Products

ARG-GLY-ASP Suppliers

Global( 185)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1100	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58

Supplier	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	58
Hebei Xinsheng New Material Technology Co., LTD.	58
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Biochempartner	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
TopScience Biochemical	58
Career Henan Chemica Co	58

View Lastest Price from ARG-GLY-ASP manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-17	ARG-GLY-ASP 99896-85-2	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2024-01-02	Arginyl-glycyl-aspartic acid 99896-85-2	US $90.00-900.00 / KG	1KG	0.98	20 tons	Zibo Hangyu Biotechnology Development Co., Ltd
2023-08-25	Arg-Gly-Asp	US $0.00-0.00 / kg	1kg	99.9%	20tons	Hebei Xinsheng New Material Technology Co., LTD.

ARG-GLY-ASP
99896-85-2
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

Arginyl-glycyl-aspartic acid
99896-85-2
US $90.00-900.00 / KG
0.98
Zibo Hangyu Biotechnology Development Co., Ltd

Arg-Gly-Asp
US $0.00-0.00 / kg
99.9%
Hebei Xinsheng New Material Technology Co., LTD.

ARG-GLY-ASP Spectrum

ARG-GLY-ASP(99896-85-2)MS

99896-85-2(ARG-GLY-ASP)Related Search:

L-Glutamic acid, N-(N-L-arginylglycyl)- H-ARG-GLY-ASP-VAL-OH H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH THYMOPOIETIN II (32-34) L-ARG-GLY-ASP-SER,H-ARG-GLY-ASP-SER-OH

HIS-GLN-VAL-SER-LEU-SER-LYS-GLN-PRO-THR-SER-GLN-PRO-ARG-GLY-ASP ARG-GLY-ASP H-ALA-PRO-ARG-GLY-ASP-OH,L-ALA-PRO-ARG-GLY-ASP ARG-LEU-ARG-PHE-ASP KL-1

H-GLY-ARG-GLY-ASP-OH H-GLY-ARG-GLY-ASP-SER-PRO-CYS-OH TRP-ASN-ARG-GLN-LEU-TYR-PRO-GLU-TRP-THR-GLU-ALA-GLN-ARG-LEU-ASP GLY-PEN-GLY-ARG-GLY-ASP-SER-PRO-CYS-ALA H-ALA-CYS-ASP-CYS-ARG-GLY-ASP-CYS-PHE-CYS-GLY-OH (DISULFIDE BRIDGE: 2-10 AND 4-8)

H-ARG-GLY-ASP-CYS-OH H-ARG-ARG-GLY-ASP-MET-GLU-OH H-GLY-ARG-GLY-ASP-THR-PRO-OH,GLY-ARG-GLY-ASP-THR-PRO

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H2N-RGD-OH H-ARG-GLY-ASP-OH L-ARG-GLY-ASP ARGINYL-GLYCYL-ASPARTIC ACID ARG-GLY-ASP ARG-GLY-ASP PEPTIDE Arg-Gly-Asp acetate Arginyl-glycyl-asparagilin F-336 L-Aspartic acid, N-(N-L-arginylglycyl)- N-(N-L-Arginylglycyl)-L-aspartic acid Rgd tripeptide sequence RGD (Arg-Gly-Asp) Peptides Arginyl - glycyl - aspartate L-Arginylglycyl-L-aspartic acid RGD RGD PEPTIDE (CORE) L-Aspartic acid, L-arginylglycyl- H-Arg-Gly-Asp-OH≥ 98% (HPLC) Arg-Gly-Asp, ≥97% (HPLC) Arg-Gly-Asp >=97% (TLC) ARG-GLY-ASP USP/EP/BP (S)-2-(2-((S)-2-Amino-5-guanidinopentanamido)acetamido)succinic acid RGD (Arg-Gly-Asp) Arg-Gly-Asp (TLC) Integrin,RGD,inhibit,Inhibitor 99896-85-2 C12H22N6O6 Cell Biology Cell Signaling and Neuroscience Extracellular Matrix Extracellular Matrix Peptides and Proteins Cytoskeleton and Extracellular Matrix BioChemical Peptide Cell Signaling Enzymes ECM ProteinsCytoskeleton and Extracellular Matrix Extracellular Matrix Extracellular Matrix Peptides (ECM) Extracellular Matrix Peptides and ProteinsPeptides for Cell Biology Fibronectin Fragments and Analogs Matrix Metalloproteinases Products Various Peptides