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Sulbactam sodium

Sulbactam sodium structure

CAS No.: 69388-84-7

Chemical Name:: Sulbactam sodium

Synonyms: Sodium Sodium;Sulbatam Sodium;SODIUM SULBACTAM;Sterile Sulbactam sodium;(2S,5R);CP-45899-2;Shu ba sodium;sulbacyam sodium;SULBACTAM SODIUM;cp45899sodiumsalt

CBNumber:: CB0370356

Molecular Formula:: C8H12NNaO5S

Molecular Weight:: 257.24

MDL Number:: MFCD01750374

MOL File:: 69388-84-7.mol

MSDS File:: SDS

Last updated:2024-04-23 19:22:53

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Sulbactam sodium Properties

Melting point	>230°C (dec.)
storage temp.	-20°C Freezer, Under Inert Atmosphere
solubility	Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids.
color	White
InChIKey	NKZMPZCWBSWAOX-IBTYICNHSA-M
CAS DataBase Reference	69388-84-7(CAS DataBase Reference)
FDA UNII	DKQ4T82YE6

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	22-24-36/37-45-24/25
HS Code	29349990
Toxicity	LD50 ivn-rat: 6500 mg/kg NKRZAZ 32(Suppl 4),97,84

Sulbactam sodium price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0000529	Sulbactam sodium European Pharmacopoeia (EP) Reference Standard	69388-84-7	y0000529	$220	2024-03-01	Buy
TRC	S699185	SulbactamSodiumSalt	69388-84-7	2g	$180	2021-12-16	Buy
TRC	S699185	SulbactamSodiumSalt	69388-84-7	50mg	$65	2021-12-16	Buy
Axon Medchem	Axon2041	Sulbactamsodium-CP45899sodium 98%	69388-84-7	25mg	$77	2021-12-16	Buy
Apolloscientific	BIS0150	Sulbactam sodium	69388-84-7	1g	$95	2021-12-16	Buy

Product number	Packaging	Price	Buy
Y0000529	y0000529	$220	Buy
S699185	2g	$180	Buy
S699185	50mg	$65	Buy
Axon2041	25mg	$77	Buy
BIS0150	1g	$95	Buy

Sulbactam sodium Chemical Properties,Uses,Production

Description

Sulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.

Chemical Properties

White Solid

Originator

Pfizer (USA)

Uses

A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.

Definition

ChEBI: Sulbactam sodium is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.

Manufacturing Process

Sulbactam sodium is semi-synthetic antibiotic of penicillinic group. Start material for it's synthesis is 6-aminopenicillanic acid. First 6-aminopenicillanic acid was isolated in 1957 year from benzylpenicilline as resalt of treating of it by penicillinaze. Benzylpenicilline is produced by microorganism of genus Streptomyces.
Further, 6-aminopenicillanic acid reacted with bromine, hydrochloric acid and NaNO2. As a result the 6,6-dibromopenicillanic acid was obtained.
6,6-Dibromopenicillanic acid was oxidized by KMnO4, to give 6,6-dibromo-1,1-The 6,6-dibromo-1,1-dioxopenicillanic acid in presence of Fe was converted to the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was treated by sodium 2-ethylhexanoate and crude sulbactam sodium was obtained.

brand name

SULPERAZONE

Therapeutic Function

Beta-lactamase inhibitor

General Description

Sulbactam was synthesized by Pfizer Research Laboratories in 1977 in the course of screening for β-lactamase inhibitors. It shows strong activity against penicillinase and moderate activity against cephalosporinase. Sulbactam itself shows activity against some gramnegative bacteria but no activity against most pathogenic bacteria. The use of sulbactam in combination with cefoperazone, which is partially hydrolyzed by penicillinase, is under study along with its use as an esterified complex with ampicillin (sultamicillin) for therapy of cefoperazone-ampicillin-resistant infections.

Safety Profile

Poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx

Sulbactam sodium Preparation Products And Raw materials

Raw materials

Sulbactam Sodium 2-ethylhexanoate

Preparation Products

3-oxopropanoic acid

Sulbactam sodium Suppliers

Global( 386)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yime New Material Technology Co., Ltd.	+86-66697723 +86-17703311139	admin@china-yime.com	China	563	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	992	58
shandong perfect biotechnology co.ltd	+86-53169958659; +8618596095638	sales@sdperfect.com	China	294	58
Hangzhou ICH Biofarm Co., Ltd	+undefined8613073685410	sales@ichemie.com	China	985	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	893	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2259	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Hubei XinRunde Chemical Co., Ltd.	+8615102730682	bruce@xrdchem.cn	CHINA	566	55

Supplier	Advantage
Hebei Yime New Material Technology Co., Ltd.	58
Sinoway Industrial co., ltd.	58
shandong perfect biotechnology co.ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Shanghai Yingrui Biopharma Co., Ltd.	60
Hubei XinRunde Chemical Co., Ltd.	55

View Lastest Price from Sulbactam sodium manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-23	Sulbactam sodium 69388-84-7	US $5.00 / kg	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-22	Sulbactam sodium 69388-84-7	US $0.00-0.00 / kg	1kg	99%	20tons	Sinoway Industrial co., ltd.
2024-04-22	Sulbactam sodium 69388-84-7	US $20.00 / KG	10KG	99%	1000KG/day	Hebei Yime New Material Technology Co., Ltd.

Sulbactam sodium
69388-84-7
US $5.00 / kg
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

Sulbactam sodium
69388-84-7
US $0.00-0.00 / kg
99%
Sinoway Industrial co., ltd.

Sulbactam sodium
69388-84-7
US $20.00 / KG
99%
Hebei Yime New Material Technology Co., Ltd.

Sulbactam sodium Spectrum

Sulbactam sodium(69388-84-7)MS

69388-84-7(Sulbactam sodium)Related Search:

ETHANE Dimethyl phthalate Dimethyl fumarate ISOHEPTANE Dimethyl sulfoxide

Sodium formate Sodium carbonate Sodium bicarbonate Sodium 1-heptanesulfonate Sulbactam

Sodium gluconate Sodium benzoate Sodium chloride N,N-Dimethylformamide Sodium hydroxide

Dimethyl sebacate Dimethyl ether Heptane

1of4

SULBACTAM SODIUM SULBACTAM SODIUM SALT sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI) (2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3,2,0]heptane-2-carboxylic acid 4,4-dioxide sodium salt sodium (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide sulbacyam sodium AMPICILLIN SODIUM AND SULBACTAM SODIUM 2:1 CP-45899-2 Penicillanic acid 4,4-dioxide sodium salt Sterile Sulbactum Sodium Powder SulbactaM SodiuM, USP (2S,5R) SulbactaM SodiuM API 3,3-dimethyl-7-oxo-4,4-dioxide-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, sodium salt (1:1) 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3,3-dimethyl-7-oxo-,4,4-d cp45899sodiumsalt penicillanicacid1,1-dioxidesodiumsalt penicillanicaciddioxidesodiumsalt penicillanicacidsulfonesodiumsalt sodium1,1-dioxopenicillanate sodiumpenicillanate1,1-dioxide sodiumsalt,(2s-cis)-ioxid Sulbactam sodium USP/EP/BP Sulbactam sodiumQ: What is Sulbactam sodium Q: What is the CAS Number of Sulbactam sodium Q: What is the storage condition of Sulbactam sodium Q: What are the applications of Sulbactam sodium Antibiotic medicine CAS 69388-84-7 veterinary sulbactam sodium sodium 3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sulbactam sodium - CP 45899 sodium Sulbactam sodium CRS SODIUM SULBACTAM Sulbatam Sodium Sodium Sodium Sterile Sulbactam sodium Shu ba sodium Natrium-(2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat-4,4-dioxid Sulbactam Sodium (100 mg) 69388-84-7 C8H10NNaO5S C8H10NO5SNa 25522 pharmaceutical raw material Antibiotic Pharmaceutical raw materials Inhibitors Pharma Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds API APIs 69388-84-7