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FARNESYLPYROPHOSPHATE

FARNESYLPYROPHOSPHATE structure

CAS No.: 13058-04-3

Chemical Name:: FARNESYLPYROPHOSPHATE

Synonyms: FPP;trans, trans-farnesyl diphosphate;FARNESYL PYROPHOSPHATE AMMONIUM SALT;FPP 3NH3;FPP 3NH4;FARNESYL-PP;FARNESYLDIPHOSPHATE;FARNESYLPYROPHOSPHATE;FARNESYL DIPHOSPHATE-TA;(E,E)-farnesyl diphosphate

CBNumber:: CB0378488

Molecular Formula:: C15H28O7P2

Molecular Weight:: 382.33

MDL Number:: MFCD00189688

MOL File:: 13058-04-3.mol

Last updated:2023-05-04 17:34:32

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FARNESYLPYROPHOSPHATE Properties

Melting point	>107°C (dec.)
Boiling point	533.8±60.0 °C(Predicted)
Density	1.233±0.06 g/cm3(Predicted)
Flash point	11 °C
storage temp.	-20°C
solubility	Methanol (Slightly, Sonicated), Water (Slightly)
form	methanol:ammonia solution
pka	1.07±0.50(Predicted)
color	White to Brown
Stability	Hygroscopic, Light Sensitive, Temperature Sensitive
FDA UNII	79W6B01D07

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS06,GHS08
Signal word	Danger
Hazard statements	H225-H301+H311+H331-H315-H319-H370
Precautionary statements	P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338
Hazard Codes	F,T
Risk Statements	11-23/24/25-39/23/24/25
Safety Statements	7-16-36/37-45
RIDADR	UN 1230 3/PG 2
WGK Germany	1

FARNESYLPYROPHOSPHATE price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	F6892	Farnesyl pyrophosphate ammonium salt methanol:ammonia solution, ≥95% (TLC)	13058-04-3	1vial	$105	2024-03-01	Buy
Sigma-Aldrich	F6892	Farnesyl pyrophosphate ammonium salt methanol:ammonia solution, ≥95% (TLC)	13058-04-3	5vials	$363	2024-03-01	Buy
Usbiological	276173	Farnesyl pyrophosphate triammonium salt	13058-04-3	1mg	$698	2021-12-16	Buy
American Custom Chemicals Corporation	BIO0000460	FARNESYL PYROPHOSPHATE AMMONIUM SALT 95.00%	13058-04-3	5MG	$501.48	2021-12-16	Buy

Product number	Packaging	Price	Buy
F6892	1vial	$105	Buy
F6892	5vials	$363	Buy
276173	1mg	$698	Buy
BIO0000460	5MG	$501.48	Buy

FARNESYLPYROPHOSPHATE Chemical Properties,Uses,Production

Uses

Farnesyl pyrophosphate ammonium salt has been used:

as a prenylation agonist in human osteogenic sarcoma cells in collagen-based cell invasion assays
in the prenylation of the hepatocyte growth factor (HGF) in human umbilical vein endothelial cells (HUVECs)
as a substrate in prenyltransferases assay in diatom Haslea ostrearia

Definition

ChEBI: 2-trans,6-trans-farnesyl diphosphate is the trans,trans-stereoisomer of farnesyl diphosphate. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a conjugate acid of a 2-trans,6-trans-farnesyl diphosphate(3-).

General Description

Farnesyl pyrophosphate is a 15-carbon isoprenoid synthesized from geranyl pyrophosphate (GPP) by the action of enzyme farnesyl pyrophosphate synthase (FPPS).

Biochem/physiol Actions

Farnesyl pyrophosphate (FPP) is the precursor for the biosynthesis of cholesterol, ubiquinone and dolicol. It is part of the intracellular mevalonate pathway. FPP is essential for cell survival and is used for prenylation of several low molecular mass G proteins, including Ras. Inhibition of prenylation results in loss of oncogenic potential of Ras proteins. Inhibition of prenylation may serve as therapeutic potential for management of synaptic plasticity and Alzheimer′s disease.

Purification Methods

Purify the pyrophosphate by chromatography on Whatman No3 MM paper in a system of isopropanol-isobutanol/ammonia/water (40:20:1:30) (v/v). Store it as the Li or NH4 salt at 0o. See geranylgeranyl pyrophosphate below.

FARNESYLPYROPHOSPHATE Preparation Products And Raw materials

Raw materials

Preparation Products

FARNESYLPYROPHOSPHATE Suppliers

Global( 42)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15878	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8018	62
Shanghai Baoyisheng Biotechnology Co., LTD	15221020695	502277408@qq.com	China	466	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Hubei yongkuo Technology Co., Ltd	027-59223108 15972152991	1248580099@qq.com	China	10007	58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd	027-027-59308705 18871579363	1248680011@qq.com	China	9984	58
Anqing Rong Chuang Biological Technology Co., Ltd.	15001988657	1367753897@qq.com	China	938	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Shanghai Macklin Biochemical Co.,Ltd.	55
Sigma-Aldrich	80
ShangHai Biochempartner Co.,Ltd	62
Shanghai Baoyisheng Biotechnology Co., LTD	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Energy Chemical	58
Hubei yongkuo Technology Co., Ltd	58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd	58
Anqing Rong Chuang Biological Technology Co., Ltd.	58

13058-04-3(FARNESYLPYROPHOSPHATE)Related Search:

farnesylpyrophosphate cyclase FARNESYLPYROPHOSPHATE OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT OCTAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT, [1-3H] Geranylgeranyl pyrophosphate

TRANS-GERANYLGERANYL-PYROPHOSPHATE, [1-3H] TRIAMMONIUM SALT FPP [1-3H] ALL TRANS-3,7,11,15-TETRAMETHYL-2,6,10,14-HEXADECATETRAENYL TRIPHOSPHATE AMMONIUM SALT 3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-YL TRIPHOSPHATE AMMONIUM SALT TRANS, TRANS FARNESYL TRIPHOSPHATE, TRIAMMONIUM SALT, [1,2-14C]

FARNESYL PYROPHOSPHATE-[1-3H(N)] TRIAMMONIUM SALT ALL TRANS GERANYL GERANYL PYROPHOSPHATE, [1-3H], TRIAMMONIUM SALT HEXAPRENYL PYROPHOSPHATE TRIAMMONIUM SALT TRANS, TRANS FARNESYL TRIPHOSPHATE, TETRAAMMONIUM SALT, [1-3H]

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FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT SOLUTION FPP, 3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-triene-1-ol diphosphoric acid (E,E)-Farnesyl pyrophosphate 3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE 3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE 3NH3 3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL PYROPHOSPHATE AMMONIUM SALT FARNESYLPYROPHOSPHATE TRIAMMONIUM SALT FARNESYLPYROPHOSPHATE FARNESYL DIPHOSPHATE-TA FPP 3NH3 FPP 3NH4 Diphosphoric acid α-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester (E,E)-farnesyl diphosphate 2-trans,6-trans-farnesyl diphosphate all-trans-farnesyl diphosphate FARNESYL-PP Farnesyl pyrophosphate ammonium salt, in ethanol FARNESYL PYROPHOSPHATE AMMONIUM 200 TRANS, TRANS FARNESYL PYROPHOSPHATE TRIAMMONIUM SALT 3,7,11-trimethyl-2,6,10-dodecatrien-1-yl pyrophosphate ammonium salt [hydroxy-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoxy]phosphoryl]oxyphosphonic acid FARNESYLDIPHOSPHATE farnesyl pyrophosphate ammonium*200 ug/vial Diphosphoric acid, P-(3,7,11-trimethyl-2,6,10-dodecatrien-1-yl) ester Farnesyl pyrophosphate ammonium salt methanol:ammonia solution FARNESYL PYROPHOSPHATE AMMONIUM SALT FPP trans, trans-farnesyl diphosphate 13058-04-3 C15H28O7P2 C15H37N3O7P2 Post-translational Modification Cell Signaling and Neuroscience Cell Biology BioChemical G Protein Function G Proteins and Cyclic Nucleotides