ChemicalBook >> CAS DataBase List >>2-Hydroxyisobutyric acid

2-Hydroxyisobutyric acid

CAS No.
594-61-6
Chemical Name:
2-Hydroxyisobutyric acid
Synonyms
2-HYDROXY-2-METHYLPROPANOIC ACID;2-hydroxyisobutyrate;ALPHA-HYDROXYISOBUTYRIC ACID;α-Hydroxyisobutyric acid;|á-Hydroxyisobutyric acid;2-HYDROXY-2-METHYLPROPIONIC ACID;Propanoic acid, 2-hydroxy-2-methyl-;(CH3)2COHCOOH;METHYL LACTIC ACID;RARECHEM AL BO 0199
CBNumber:
CB0379920
Molecular Formula:
C4H8O3
Molecular Weight:
104.1
MDL Number:
MFCD00004459
MOL File:
594-61-6.mol
MSDS File:
SDS
Last updated:2023-09-08 17:00:39

2-Hydroxyisobutyric acid Properties

Melting point 76-80 °C(lit.)
Boiling point 84 °C1.5 mm Hg(lit.)
Density 11412
refractive index 1.4761 (estimate)
Flash point 114°C/12mm
storage temp. Sealed in dry,Room Temperature
solubility water: soluble10%, clear to very slightly hazy, colorless
form Solid
pka pK1:3.717 (25°C,μ=0.1)
color White to Off-White
Water Solubility Soluble in water, ether, alcohol, methanol and hot benzene.
BRN 1744739
LogP -0.360
CAS DataBase Reference 594-61-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII DMW250U2HF
NIST Chemistry Reference Propanoic acid, 2-hydroxy-2-methyl-(594-61-6)
EPA Substance Registry System Propanoic acid, 2-hydroxy-2-methyl- (594-61-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P261-P264-P280-P304+P340+P312-P305+P351+P338+P310-P403+P233
Hazard Codes  Xi
Risk Statements  37/38-41-36/37/38
Safety Statements  26-39-25-36
WGK Germany  3
Hazard Note  Irritant
TSCA  Yes
HS Code  29181980
NFPA 704
1
2 0

2-Hydroxyisobutyric acid price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 323594 α-Hydroxyisobutyric acid 99% 594-61-6 25g $56.5 2024-03-01 Buy
Sigma-Aldrich 164976 α-Hydroxyisobutyric acid 98% 594-61-6 25g $41.6 2024-03-01 Buy
TCI Chemical M0360 2-Hydroxyisobutyric Acid >98.0%(T) 594-61-6 25g $26 2024-03-01 Buy
TCI Chemical M0360 2-Hydroxyisobutyric Acid >98.0%(T) 594-61-6 100g $65 2024-03-01 Buy
Alfa Aesar A13146 2-Hydroxyisobutyric acid, 99% (dry wt.), water <2% 594-61-6 25g $29.65 2024-03-01 Buy
Product number Packaging Price Buy
323594 25g $56.5 Buy
164976 25g $41.6 Buy
M0360 25g $26 Buy
M0360 100g $65 Buy
A13146 25g $29.65 Buy

2-Hydroxyisobutyric acid Chemical Properties,Uses,Production

Chemical Properties

white to off-white needle-like crystals or

Uses

α-Hydroxyisobutyric acid was used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Uses

2-Hydroxyisobutyric acid is used as an electrolyte in the separation of the metal ions by on-line cyclic voltammetry. It is also used as a building block for the synthesis of polymers. Its conjugate base, 2-hydroxybutyrate is utilized to catabolize L-threonine as well as synthesize glutathione. Further, it is used as an indicator for the early detection insulin resistance in non-diabetic subjects.

Uses

2-Hydroxyisobutyric acid is used as background electrolyte for separation and detection of the metal ions by on-line cyclic voltammetry.

Definition

ChEBI: A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether.

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1488, 1958 DOI: 10.1021/jo01104a022

General Description

α-Hydroxyisobutyric acid (2-hydroxyisobutyric acid) is the building block for polymer synthesis. It forms complexes with Eu(III) and has been studied by time resolved fluorescence spectroscopy.

498-24-8
79-41-4
498-23-7
594-61-6
97-65-4
Synthesis of 2-Hydroxyisobutyric acid from Mesaconic acid
Global( 371)Suppliers
Supplier Tel Email Country ProdList Advantage
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14764 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Changzhou Carman Chemical Co., Ltd.
15061933924 CHINA 514 58

View Lastest Price from 2-Hydroxyisobutyric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Hydroxyisobutyric acid pictures 2023-09-08 2-Hydroxyisobutyric acid
594-61-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
2-Hydroxyisobutyric acid pictures 2023-05-27 2-Hydroxyisobutyric acid
594-61-6
US $100.00 / kg 25kg 99% 500t/month Henan Bao Enluo International TradeCo.,LTD
2-Hydroxyisobutyric Acid pictures 2023-03-06 2-Hydroxyisobutyric Acid
594-61-6
US $19.00 / KG 1KG 99.% 50 ton Hebei Guanlang Biotechnology Co,.LTD
Propanoic acid, 2-methyl-2-hydroxy- A-HYDROXY-ISO-BUTYRIC ACID 2-MethyllaCLic Acid alpha-Hydroxyisobutyric acid 98% 2-Hydroxyisobutyric acid for synthesis RARECHEM AL BO 0199 alpha-Hydroxyisobutanoic acid Hydroxydimethylacetic acid Hydroxyisobutyricacid Lactic acid, 2-methyl- Lactic acid, 2-methyl-, L- (CH3)2COHCOOH 2-hydroxy-2-methyl-propanoicaci 2,2-DIMETHYLGLYCOLIC ACID 2-HYDROXYISOBUTYRIC ACID 2-METHYLLACTIC ACID METHYL LACTIC ACID 2-Hydroxy-#niso-butyric acid 2 2-Hydroxyisobutyric Acid 2,4-dichlorodibenzoyl peroxide 2-hydroxy-2-methylpropanoate 2-HYDROXYISOBUTYRIC ACID (2-HYDROXY-2-METHYLPROPIONIC ACID) 2-Hydroxyisobutyricacid,99% PROPANOICACID,2-HYDROXY-2- Hydroxy-2-methylpropanoic acid, 2-: (2-Methyllactic acid) 2-Hydroxy-2-methylpropionic acid, 2-Methyllactic acid 2-Hydroxyisobutyric acid,98% α-Hydroxyisobutyric acid,2-Hydroxy-2-methylpropionic acid, 2-Methyllactic acid 2-Hydroxyisobutanoic acid 2-Hydroxyisobutyric acid, 99% (dry wt.), water <2% 2-Hydroxyisobutyric 2-Hydroxyisobutyric acid, 98% 25GR 2-HydroxyisobutyricAcid> 2-hydroxyisobutyricaci 2-methyl-2-hydroxypropanoic acid ALPHA-HYDROXYISOBUTYRIC ACID 2-HYDROXY-2-METHYLPROPIONIC ACID 2-HYDROXY-2-METHYLPROPANOIC ACID Propanoic acid, 2-hydroxy-2-methyl- |á-Hydroxyisobutyric acid α-Hydroxyisobutyric acid 2-hydroxyisobutyrate 594-61-6 C4H8O3 CH32CHOHCOOH Building Blocks Carboxylic Acids Carbonyl Compounds C1 to C5 Organic Building Blocks Carboxylic Acids Chemical Synthesis Organic Building Blocks FINE Chemical & INTERMEDIATES Organic acids Building Blocks C1 to C5 Carbonyl Compounds