1-Indanone
- CAS No.
- 83-33-0
- Chemical Name:
- 1-Indanone
- Synonyms
- 2,3-Dihydro-1H-inden-1-one;INDANONE;1H-INDEN-1-ONE, 2,3-DIHYDRO-;IDO;INDO;2,3-Dihydro-1-indanone;Indone;INDAN-1-ONE;1-Indone;1-INDENONE
- CBNumber:
- CB0384120
- Molecular Formula:
- C9H8O
- Molecular Weight:
- 132.16
- MDL Number:
- MFCD00003785
- MOL File:
- 83-33-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-Indanone ≥99% | I2304 | 10g | $72.1 |
| 1-Indanone ≥99% | I2304 | 25g | $114 |
| Anti-IDO1 antibody produced in goat affinity isolated antibody, buffered aqueous solution | SAB2501926 | 100μg | $628 |
| ANTI-INDO antibody produced in mouse clone 1C1, purified immunoglobulin, buffered aqueous solution | SAB1411918 | 100μg | $541 |
| ANTI-INDO antibody produced in mouse clone 1C5, purified immunoglobulin, buffered aqueous solution | SAB1411917 | 100μg | $541 |
| More product size | |||
| Melting point | 38-40 °C(lit.) |
|---|---|
| Boiling point | 243-245 °C(lit.) |
| Density | 1.103 g/mL at 25 °C(lit.) |
| refractive index | 1.5610 (estimate) |
| Flash point | 233 °F |
| storage temp. | Store below +30°C. |
| solubility | 6.5g/l |
| form | Crystalline Mass |
| color | Light yellow to brown |
| Odor | Rather weak, woody and somewhat medicinal odor with an incense-like undertone. |
| biological source | mouse |
| Odor Threshold | 0.0088ppm |
| Water Solubility | 6.5 g/L (20 C) |
| BRN | 507957 |
| Stability | Light sensitive |
| InChI | 1S/C9H8O/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4H,5-6H2 |
| InChIKey | QNXSIUBBGPHDDE-UHFFFAOYSA-N |
| SMILES | O=C1CCc2ccccc12 |
| CAS DataBase Reference | 83-33-0(CAS DataBase Reference) |
| FDA UNII | V7021Y717I |
| NIST Chemistry Reference | 1H-Inden-1-one, 2,3-dihydro-(83-33-0) |
| EPA Substance Registry System | 1H-Inden-1-one, 2,3-dihydro- (83-33-0) |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312a-P330-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| Autoignition Temperature | 525 °C | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29143900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
1-Indanone price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I2304 | 1-Indanone ≥99% | 83-33-0 | 10g | $72.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | I2304 | 1-Indanone ≥99% | 83-33-0 | 25g | $114 | 2026-04-30 | Buy |
| Sigma-Aldrich | SAB2501926 | Anti-IDO1 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 83-33-0 | 100μg | $628 | 2026-04-30 | Buy |
| Sigma-Aldrich | SAB1411918 | ANTI-INDO antibody produced in mouse clone 1C1, purified immunoglobulin, buffered aqueous solution | 83-33-0 | 100μg | $541 | 2025-07-31 | Buy |
| Sigma-Aldrich | SAB1411917 | ANTI-INDO antibody produced in mouse clone 1C5, purified immunoglobulin, buffered aqueous solution | 83-33-0 | 100μg | $541 | 2025-07-31 | Buy |
1-Indanone Chemical Properties,Uses,Production
Description
1-Indanone is an important skeletal structure with a wide range of biological activities. Extensive research has demonstrated that 1-indanone derivatives play a significant role in the development of drugs for the treatment of Alzheimer's disease, as well as in anti-diarrhoeal, anti-proliferative, antibacterial, anti-inflammatory and anti-cancer agents[1].
Chemical Properties
Pale yellow liquid
Uses
1-Indanone is an oxidation product of indan, a component of fuels, solvents and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.
Uses
1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.
Definition
ChEBI: An indanone that consists of 2,3-dihydro-1H-indene substituted by an oxo group at position 1.
Synthesis Reference(s)
The Journal of Organic Chemistry, 54, p. 1144, 1989 DOI: 10.1021/jo00266a028
Journal of the American Chemical Society, 99, p. 4822, 1977 DOI: 10.1021/ja00456a048
Tetrahedron Letters, 27, p. 3139, 1986 DOI: 10.1016/S0040-4039(00)84736-X
Biological Activity
Indoleamine 2,3 dioxygenase (IDO) 1 plays an important role in the metabolism of tryptophan and in immune regulation. Removal of IDO1 results in attenuated contact hypersensitivity (CHS) responses.
Synthesis
1-Indanone is produced by cyclization of be{a-Phenylpropionyl chloride in Benzene.
References
[1] Mei Zuo . (2025). Synthesis, X-ray, DFT and antibacterial activity of a novel 1-indanone derivative. Journal of Molecular Structure, 1339, Article 142422. https://doi.org/10.1016/j.molstruc.2025.142422
1-Indanone Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JIAOZUO YAXIN CHEMICAL IMDUSTRY CO., LTD | +undefined13393895309 | purchase@yaxinchemical.com | China | 27 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 | sales@sjar-tech.com | China | 529 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
View Lastest Price from 1-Indanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-30 | 1-Indanone
83-33-0
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
![]() |
2026-04-30 | 1-Indanone
83-33-0
|
US $0.00 / g | 1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | |
![]() |
2026-04-22 | 1-Indanone
83-33-0
|
US $0.00 / removed | 99.91% | 10g | TargetMol Chemicals Inc. |
-

- 1-Indanone
83-33-0
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- 1-Indanone
83-33-0
- US $0.00 / g
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-

- 1-Indanone
83-33-0
- US $0.00 / removed
- 99.91%
- TargetMol Chemicals Inc.
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