ChemicalBook >> CAS DataBase List >>1-Indanone

1-Indanone

CAS No.
83-33-0
Chemical Name:
1-Indanone
Synonyms
2,3-Dihydro-1H-inden-1-one;INDANONE;1H-INDEN-1-ONE, 2,3-DIHYDRO-;IDO;INDO;2,3-Dihydro-1-indanone;Indone;INDAN-1-ONE;1-Indone;1-INDENONE
CBNumber:
CB0384120
Molecular Formula:
C9H8O
Molecular Weight:
132.16
MDL Number:
MFCD00003785
MOL File:
83-33-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
1-Indanone ≥99% I2304 10g $72.1
1-Indanone ≥99% I2304 25g $114
Anti-IDO1 antibody produced in goat affinity isolated antibody, buffered aqueous solution SAB2501926 100μg $628
ANTI-INDO antibody produced in mouse clone 1C1, purified immunoglobulin, buffered aqueous solution SAB1411918 100μg $541
ANTI-INDO antibody produced in mouse clone 1C5, purified immunoglobulin, buffered aqueous solution SAB1411917 100μg $541
More product size

1-Indanone Properties

Melting point 38-40 °C(lit.)
Boiling point 243-245 °C(lit.)
Density 1.103 g/mL at 25 °C(lit.)
refractive index 1.5610 (estimate)
Flash point 233 °F
storage temp. Store below +30°C.
solubility 6.5g/l
form Crystalline Mass
color Light yellow to brown
Odor Rather weak, woody and somewhat medicinal odor with an incense-like undertone.
biological source mouse
Odor Threshold 0.0088ppm
Water Solubility 6.5 g/L (20 C)
BRN 507957
Stability Light sensitive
InChI 1S/C9H8O/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4H,5-6H2
InChIKey QNXSIUBBGPHDDE-UHFFFAOYSA-N
SMILES O=C1CCc2ccccc12
CAS DataBase Reference 83-33-0(CAS DataBase Reference)
FDA UNII V7021Y717I
NIST Chemistry Reference 1H-Inden-1-one, 2,3-dihydro-(83-33-0)
EPA Substance Registry System 1H-Inden-1-one, 2,3-dihydro- (83-33-0)
UNSPSC Code 12352203
NACRES NA.41

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
Autoignition Temperature 525 °C
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29143900
Storage Class 11 - Combustible Solids
NFPA 704
1
1 0

1-Indanone price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I2304 1-Indanone ≥99% 83-33-0 10g $72.1 2026-04-30 Buy
Sigma-Aldrich I2304 1-Indanone ≥99% 83-33-0 25g $114 2026-04-30 Buy
Sigma-Aldrich SAB2501926 Anti-IDO1 antibody produced in goat affinity isolated antibody, buffered aqueous solution 83-33-0 100μg $628 2026-04-30 Buy
Sigma-Aldrich SAB1411918 ANTI-INDO antibody produced in mouse clone 1C1, purified immunoglobulin, buffered aqueous solution 83-33-0 100μg $541 2025-07-31 Buy
Sigma-Aldrich SAB1411917 ANTI-INDO antibody produced in mouse clone 1C5, purified immunoglobulin, buffered aqueous solution 83-33-0 100μg $541 2025-07-31 Buy
Product number Packaging Price Buy
I2304 10g $72.1 Buy
I2304 25g $114 Buy
SAB2501926 100μg $628 Buy
SAB1411918 100μg $541 Buy
SAB1411917 100μg $541 Buy

1-Indanone Chemical Properties,Uses,Production

Description

1-Indanone is an important skeletal structure with a wide range of biological activities. Extensive research has demonstrated that 1-indanone derivatives play a significant role in the development of drugs for the treatment of Alzheimer's disease, as well as in anti-diarrhoeal, anti-proliferative, antibacterial, anti-inflammatory and anti-cancer agents[1].

Chemical Properties

Pale yellow liquid

Uses

1-Indanone is an oxidation product of indan, a component of fuels, solvents and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.

Uses

1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.

Definition

ChEBI: An indanone that consists of 2,3-dihydro-1H-indene substituted by an oxo group at position 1.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 1144, 1989 DOI: 10.1021/jo00266a028
Journal of the American Chemical Society, 99, p. 4822, 1977 DOI: 10.1021/ja00456a048
Tetrahedron Letters, 27, p. 3139, 1986 DOI: 10.1016/S0040-4039(00)84736-X

Biological Activity

Indoleamine 2,3 dioxygenase (IDO) 1 plays an important role in the metabolism of tryptophan and in immune regulation. Removal of IDO1 results in attenuated contact hypersensitivity (CHS) responses.

Synthesis

1-Indanone is produced by cyclization of be{a-Phenylpropionyl chloride in Benzene.

References

[1] Mei Zuo . (2025). Synthesis, X-ray, DFT and antibacterial activity of a novel 1-indanone derivative. Journal of Molecular Structure, 1339, Article 142422. https://doi.org/10.1016/j.molstruc.2025.142422

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View Lastest Price from 1-Indanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Indanone pictures 2026-04-30 1-Indanone
83-33-0
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
1-Indanone  pictures 2026-04-30 1-Indanone
83-33-0
US $0.00 / g 1g More Than 99% 100kg/Month BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
1-Indanone pictures 2026-04-22 1-Indanone
83-33-0
US $0.00 / removed 99.91% 10g TargetMol Chemicals Inc.
  • 1-Indanone pictures
  • 1-Indanone
    83-33-0
  • US $0.00 / KG
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • 1-Indanone  pictures
  • 1-Indanone
    83-33-0
  • US $0.00 / g
  • More Than 99%
  • BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
  • 1-Indanone pictures
  • 1-Indanone
    83-33-0
  • US $0.00 / removed
  • 99.91%
  • TargetMol Chemicals Inc.
A-HYDRINDONE 2,3-dihydro-1h-inden-1-on 2,3-Dihydro-1-indenone alpha-Indanone INDANONE(1-) ALPHA-HYDRINDON AKOS 92310 1-OXOINDANE 1-OXOHYDRINDENE 1-OXOINDAN 1-KETOHYDRINDENE 1-INDANONE 1-HYDROINDONE 1-HYDRINDONE α-Hydrindone Indan-1-one 98% 1-INDANONE (1H-INDEN-1-ONE, 2,3-DIHYDRO) 1-INDANONE, 99+% 1-Indanone ,98% I-Indanone 1-Indanone,α-Hydrindone 1H-Indan-1-one 3-Dihydro-1H-inden-1-one NSC 2581 alpha-Hydrindone 1-Hydroindone 1-Ketohydrindene 1-Ketohydroindene α-Hydroindone 1-Indanone, 99+% 10GR 1-Indanone, 99+% 25GR 2,3-Dihydro-1H-inden-1-one, 2,3-Dihydro-1-oxo-1H-indene ANTI-INDO antibody produced in mouse LAMP-2 LAMPB LGP110 Anti-IDO1 antibody produced in goat HGNC:6059 indoleamine-pyrrole 2,3 dioxygenase 1- twohydrogenindone 1-Indanone ReagentPlus(R), >=99% 1-Indanone Vetec(TM) reagent grade, 98% 4-fluorosulfonylbenzoic acid [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl ester hydrochloride Rasagiline Impurity 11 I**1-Indanone 1-Indanone> 1-INDANONE FOR SYNTHESIS 25 G 1- ketones Recombinant Human CD107B/LAMP2 Protein, His Tag Recombinant Human LAMP2 Protein, His Tag 1-INDANONE ( RASAGILINE) 1-Indone 2,3-Dihydro-1-indanone Dihydro-1-indenone INDAN-1-ONE ALPHA-HYDRINDONE 2,3-DIHYDROINDEN-1-ONE Indone 1-INDENONE INDO