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N-Hydroxysuccinimide

N-Hydroxysuccinimide
N-Hydroxysuccinimide
CAS No.
6066-82-6
Chemical Name:
N-Hydroxysuccinimide
Synonyms
NHS;HOSU;HONSU;AKOS 91864;NHS OR HONSU;HOSu Novabiochem;Hydroxysuccinimide;N-HYDROXYSUCCINIMDE;N-HYDROXYSUCCINAMIDE;1-Hydroxysuccinimide
CBNumber:
CB0391283
Molecular Formula:
C4H5NO3
Formula Weight:
115.09
MOL File:
6066-82-6.mol

N-Hydroxysuccinimide Properties

Melting point:
95-98 °C(lit.)
Boiling point:
215.33°C (rough estimate)
Density 
1.4769 (rough estimate)
refractive index 
1.4080 (estimate)
storage temp. 
2-8°C
form 
Liquid or Solid
color 
Clear yellow-brown to brown
PH
5-7 (50g/l, H2O, 20℃)
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
BRN 
113913
Stability:
Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture.
InChIKey
NQTADLQHYWFPDB-UHFFFAOYSA-N
CAS DataBase Reference
6066-82-6(CAS DataBase Reference)
NIST Chemistry Reference
N-hydroxylsuccinimide(6066-82-6)
EPA Substance Registry System
2,5-Pyrrolidinedione, 1-hydroxy-(6066-82-6)

SAFETY

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-26-36
WGK Germany  3
Hazard Note  Irritant
TSCA  Yes
HS Code  29251995

N-Hydroxysuccinimide price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 130672 N-Hydroxysuccinimide 98% 6066-82-6 1kg $751 2018-11-13 Buy
Sigma-Aldrich 130672 N-Hydroxysuccinimide 98% 6066-82-6 5kg $2130 2018-11-13 Buy
TCI Chemical B0249 N-Hydroxysuccinimide [Coupling Reagent for Peptide] >98.0%(GC)(T) 6066-82-6 25g $88 2018-11-22 Buy
TCI Chemical H0623 N-Hydroxysuccinimide >98.0%(T) 6066-82-6 25g $31 2018-11-22 Buy
Alfa Aesar A10312 N-Hydroxysuccinimide, 98+% 6066-82-6 25g $34.5 2018-11-13 Buy

N-Hydroxysuccinimide Chemical Properties,Uses,Production

Chemical Properties

White to pale yellow

Uses

Reagent for preparation of active esters of amino acids.

Uses

Useful in the carbodiimide method for improved amidations and peptide couplings.

Uses

Additive used in the carbodiimide method for improved amidations and peptide couplings.

Uses

N-hydroxysuccinimide (NHS) is often used to assist carbodiimide-mediated peptide coupling by forming an active ester intermediate via condensation of the surface carboxyl group and NHS. The NHS-reactive ester intermediate is susceptible to nucleophilic attack by primary amines and results in the formation of stable amide bonds between the biomaterial surface and the N-terminus of the peptide.

Purification Methods

Recrystallise the imide from EtOH/ethyl acetate [Manesis & Goodmen J Org Chem 52 5331 1987]. [Beilstein 21/9 V 498.]

N-Hydroxysuccinimide Preparation Products And Raw materials

Raw materials

Preparation Products


N-Hydroxysuccinimide Suppliers

Global( 482)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19953 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Fluoropharm Co., Ltd.
+8613336034509
sales@fluoropharm.com CHINA 735 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14293 60
AB PharmaTech,LLC
323-480-4688
323-480-4688 sales01@abpharmatechusa.com United States 991 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1659 55
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com
+86-571-87063838 jocelynpan@zjarts.com CHINA 664 58

View Lastest Price from N-Hydroxysuccinimide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-07 N-Hydroxysuccinimide
6066-82-6
US $1.00 / KG 1KG 99% Customized career henan chemical co

N-Hydroxysuccinimide Spectrum


6066-82-6(N-Hydroxysuccinimide)Related Search:


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  • 1-Hydroxypyrrolidine-2,5-dione, 2,5-Dioxo-1-hydroxypyrrolidine
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  • N-HydroxysucciniMide puruM, >=97.0% (T)
  • N - butyl hydroxy diiMide
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