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DEOXYNIVALENOL

DEOXYNIVALENOL
DEOXYNIVALENOL structure
CAS No.
51481-10-8
Chemical Name:
DEOXYNIVALENOL
Synonyms
DON;rdtoxin;VOMITOXIN;NSC 269144;Vomintoxin;DON solution;DEOXYNIVALENOL;DON, Vomitoxin;desoxynivalenol;4-deoxynivalenol
CBNumber:
CB0391546
Molecular Formula:
C15H20O6
Formula Weight:
296.32
MOL File:
51481-10-8.mol

DEOXYNIVALENOL Properties

Melting point:
151-153 C
alpha 
D25+6.35° (c = 0.07 in ethanol)
Boiling point:
357.92°C (rough estimate)
Density 
1.48
refractive index 
1.4359 (estimate)
Flash point:
-3 °C
storage temp. 
2-8°C
form 
solution (ethanol: 2-propanol 95:5)
Merck 
13,10092
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
51481-10-8
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,Xn,F,Xi
Risk Statements  25-68/20/21/22-67-66-36-20/21/22-11-36/37/38
Safety Statements  36/37/39-45-36-26-16-36/37-37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  YD0167000
HazardClass  6.1(a)
PackingGroup  I
HS Code  29329990
Toxicity LD50 i.p. in male, female mice (mg/kg): 70.0, 76.7 (Yoshizawa, Morooka)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.

DEOXYNIVALENOL price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34124 Deoxynivalenol solution 100 μg/mL in acetonitrile, analytical standard 51481-10-8 2ml $334 2018-11-13 Buy
Sigma-Aldrich 32943 Deoxynivalenol reference material 51481-10-8 5mg $525 2018-11-13 Buy
Cayman Chemical 11428 4-deoxy Nivalenol ≥98% 51481-10-8 500μg $43 2018-11-19 Buy
Cayman Chemical 11428 4-deoxy Nivalenol ≥98% 51481-10-8 1mg $65 2018-11-19 Buy
Sigma-Aldrich D0156 Deoxynivalenol 51481-10-8 1mg $89.6 2018-11-13 Buy

DEOXYNIVALENOL Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Deoxynivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye. This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects. It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity. It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.

Uses

Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.

DEOXYNIVALENOL Preparation Products And Raw materials

Raw materials

Preparation Products


DEOXYNIVALENOL Suppliers

Global( 55)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
BOC Sciences
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J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
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86-21-50328109 3bsc@sina.com China 15882 69
ZHIWE CHEMTECH CO LTD 021-20221225;13917446399;QQ:2381298399
sales@zhiwe.net;zwchem@163.com China 470 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-50426030
86-021-50426522,50426273 sales@jingyan-chemical.com China 10012 60
Chemsky(shanghai)International Co.,Ltd. 021-50135380
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Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9851 79
Dalian Meilun Biotech Co., Ltd. 0411-66771943;0411-66771942
0411-66771945 sales@meilune.com China 4062 58
ShangHai YuanYe Biotechnology Co., Ltd. 021-61312847 qq:2797782341
021-55068248 2797782341@qq.com China 7215 60

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