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Tolperisone

Tolperisone structure

CAS No.: 728-88-1

Chemical Name:: Tolperisone

Synonyms: mydeton;Mideton;Mydetone;AKOS 91983;NSC 107321;TOLPERISONE;dl-Tolperisone;Atmosgen free base;Besnoline free base;Tolperisone USP/EP/BP

CBNumber:: CB0393580

Molecular Formula:: C16H23NO

Molecular Weight:: 245.36

MDL Number:: MFCD00242995

MOL File:: 728-88-1.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:41

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Tolperisone Properties

Melting point	176.5°C
Boiling point	388.33°C (rough estimate)
Density	0.9672 (rough estimate)
refractive index	1.5500 (estimate)
pka	8.47±0.10(Predicted)
CAS DataBase Reference	728-88-1(CAS DataBase Reference)
FDA UNII	F5EOM0LD8E
ATC code	M02AX06,M03BX04

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H332-H312-H302
Precautionary statements	P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501

Tolperisone price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0008765	TOLPERISONE 95.00%	728-88-1	1KG	$6985.44	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0008765	1KG	$6985.44	Buy

Tolperisone Chemical Properties,Uses,Production

Originator

Tolperisone hydrochloride,Shanghai Abochem Chemical Co.

Definition

ChEBI: 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone is an aromatic ketone.

Manufacturing Process

To 1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanol in chloroform was added an excess of thionyl chloride and the reaction mixture refluxed until completed. It was then taken to dryness under reduced pressure and the residue crystallized by dissolving in hot alcohol and diluting with ethyl acetate. An aqueous solution of the obtained N-[3-chloro-3-(p-tolyl)propyl]piperidine hydrochloride was hydrogenated at 3 atmospheres in the presence of buffered palladium-on-charcoal catalyst. 1-Piperidino-2-methyl-3-(p-tolyl)-3-propanone was purified by distilling the base (boiling point 106-107°C/1 mm) and reconverting to the hydrochloride, melting point 216-217°C.

brand name

Tolperisone Hydrochloride is JAN.

Therapeutic Function

Muscle relaxant, Vasodilator

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 42, p. 1676, 1994 DOI: 10.1248/cpb.42.1676

Tolperisone Preparation Products And Raw materials

Raw materials

Paraformaldehyde

Preparation Products

Tolperisone Suppliers

Global( 54)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Casorganics US Corp	+17326109938	sales@casorganics.com	CHINA	174	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3537	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Casorganics US Corp	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from Tolperisone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-12	Tolperisone 728-88-1	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
	2020-05-12	Tolperisone 728-88-1	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd

Tolperisone
728-88-1
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Tolperisone
728-88-1
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

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AKOS 91983 1-piperidino-2-methyl-3-(p-tolyl)-3-propanone 2,4’-dimethyl-3-piperidino-propiophenon 2-methyl-3-piperidino-1-p-tolylpropan-1-one mydeton TOLPERISONE α,4'-Dimethyl-β-piperidinopropiophenone 2-methyl-1-(4-methylphenyl)-3-piperidin-1-yl-propan-1-one 2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one 2-methyl-1-(4-methylphenyl)-3-piperidino-propan-1-one 1-Propanone, 2-Methyl-1-(4-Methylphenyl)-3-(1-piperidinyl)- 2'4-Dimethyl-3-PiperidylPropiophenone 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)- (9CI) dl-Tolperisone Mideton Mydetone NSC 107321 Propiophenone, 2,4'-dimethyl-3-piperidino- (7CI, 8CI) Tolperisone (base and/or unspecified salts) 2,4'-Dimethyl-3-piperidinopropiophenone 2-Methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone Tolperisone USP/EP/BP TolperisoneQ: What is Tolperisone Q: What is the CAS Number of Tolperisone Q: What is the storage condition of Tolperisone Q: What are the applications of Tolperisone 728-88-1 Tolperisone C16H23NO Tolperisone free base Atmosgen free base Besnoline free base 2-methyl-3-(piperidin-1-yl)-1-(p-tolyl)propan-1-one 728-88-1