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DM1-SPP

DM1-SPP structure

CAS No.: 452072-20-7

Chemical Name:: DM1-SPP

Synonyms: DM1-SPP;SPP-DM1;Maytansine, N2'-deacetyl-N2'-[3-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1-methyl-4-oxobutyl]dithio]-1-oxopropyl]-

CBNumber:: CB03959882

Molecular Formula:: C44H59ClN4O14S2

Molecular Weight:: 967.54

MDL Number:: MFCD28400101

MOL File:: 452072-20-7.mol

Last updated:2025-04-18 09:51:29

Product description	Number	Pack Size	Price
SPP-DM1	CS-0104940	50mg	$8046

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DM1-SPP Properties

Density	1.39±0.1 g/cm3(Predicted)
pka	9.82±0.70(Predicted)
form	Solid
color	White to off-white

DM1-SPP price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0104940	SPP-DM1	452072-20-7	50mg	$8046	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0104940	50mg	$8046	Buy

DM1-SPP Chemical Properties,Uses,Production

Uses

SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].

IC 50

Maytansinoids

References

[1] Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules. DOI:10.1158/1535-7163.MCT-10-0644

DM1-SPP Preparation Products And Raw materials

Raw materials

Preparation Products

DM1-SPP Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32435	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9729	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29641	58
Guangzhou Junze Biotechnology Co., Ltd.	17688489295		CHINA	188	58

Supplier	Advantage
BOC Sciences	58
TargetMol Chemicals Inc.	58
Fan De(Beijing) Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Guangzhou Junze Biotechnology Co., Ltd.	58

Maytansine, N2'-deacetyl-N2'-[3-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1-methyl-4-oxobutyl]dithio]-1-oxopropyl]- SPP-DM1 DM1-SPP 452072-20-7 C44H59ClN4O14S2