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Benzathine benzylpenicillin

Description
Benzathine benzylpenicillin
Benzathine benzylpenicillin structure
CAS No.
1538-09-6
Chemical Name:
Benzathine benzylpenicillin
Synonyms
neolin;penadur;cillenta;benzapen;bicillin;dibencil;leomypen;longicil;moldamin;pendepon
CBNumber:
CB0400046
Molecular Formula:
C48H56N6O8S2
Formula Weight:
909.12
MOL File:
1538-09-6.mol

Benzathine benzylpenicillin Properties

Melting point:
123-124°
alpha 
D25 +206° (c = 0.105 in formamide)
solubility 
Very slightly soluble in water, freely soluble in dimethylformamide and in formamide, slightly soluble in ethanol (96 per cent).
form 
neat
CAS DataBase Reference
1538-09-6
EPA Substance Registry System
4-Thia-1-azabicyclo[ 3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl) amino]- (2S,5R,6R)-, compd. with N,N'-bis(phenylmethyl)- 1,2-ethanediamine (2:1)(1538-09-6)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22-42/43
Safety Statements  36
WGK Germany  3
RTECS  XH9425000
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 Wear respiratory protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Benzathine benzylpenicillin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 31735 Benzathine penicilline G tetrahydrate VETRANAL 1538-09-6 250mg $51.2 2018-11-20 Buy
Sigma-Aldrich B0500000 Benzathine benzylpenicillin 1538-09-6 b0500000 $179 2018-11-23 Buy

Benzathine benzylpenicillin Chemical Properties,Uses,Production

Description

Benzathine penicillin and procaine penicillin is an antibiotic that fights bacteria in your body. Benzathine penicillin and procaine penicillin is used to treat many different types of severe infections, including strep and staph infections, diphtheria, meningitis, gonorrhea, and syphilis. It is also used to prevent rheumatic fever. It is given by injection into a muscle. Belonging to a penicillin-class drug, its mechanism of action is inhibiting the cell wall synthesis of bacteria, further killing bacteria.

Chemical Properties

White or almost white powder.

Uses

Penicillin antibacterial.

Clinical Use

Since penicillin G benzathine, N,N'-dibenzylethylenediaminedipenicillin G (Bicillin, Permapen), is the salt of a diamine,2 moles of penicillin are available from each molecule. It isvery insoluble in water, requiring about 3,000 mL to dissolve1 g. This property gives the compound great stabilityand prolonged duration of effect. At the pH of gastric juice,it is quite stable, and food intake does not interfere with itsabsorption. It is available in tablet form and in several parenteralpreparations. The activity of penicillin G benzathineis equivalent to 1,211 units/mg.Several other amines have been used to make penicillinsalts, and research is continuing on this subject. Otheramines that have been used include 2-chloroprocaine; L-Nmethyl-1,2-diphenyl-2-hydroxyethylamine (L-ephenamine);dibenzylamine; tripelennamine (Pyribenzamine); and N,N'-bis-(dehydroabietyl)ethylenediamine (hydrabamine).

Benzathine benzylpenicillin Preparation Products And Raw materials

Raw materials

Preparation Products


Benzathine benzylpenicillin Suppliers

Global( 65)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
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0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
PI & PI BIOTECH INC.
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Chemwill Asia Co.,Ltd.
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86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
XiaoGan ShenYuan ChemPharm co,ltd Tell:86-712-2580635 Mobile:15527768850 . 15527768836
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Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
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Jinan Haohua Industry Co., Ltd 0531-58773082 ;58773060
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Shanghai LiuShi Pharmaceutical Technology Co., Ltd. 021-60135539
021-38721356 shlschemical@hotmail.com China 9947 55
S.Z. PhyStandard Bio-Tech. Co., Ltd. 17727448752,0755-83725681-603
+86 755 28094224 rex.liu@phystandard.com;tom.liu@phystandard.com China 4535 50

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