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Vitamin A palmitate

Vitamin A palmitate
Vitamin A palmitate structure
Chemical Name:
Vitamin A palmitate
AROVIT;C02588;Optovit-A;Nanoactive A;BioActive VA;NanoActive VA;Retinylpalmitat;RETINYL PALMITATE;RETINOL PALMITATE;Soluble Vitamin A
Molecular Formula:
Formula Weight:
MOL File:

Vitamin A palmitate Properties

Melting point:
Boiling point:
546.51°C (rough estimate)
0.9668 (rough estimate)
refractive index 
1.5250 (estimate)
Flash point:
storage temp. 
Specific Gravity
0.90~0.93 (20℃)
Water Solubility 
Soluble in chloroform, ether, and vegetable oils. Insoluble in water.
CAS DataBase Reference
79-81-2(CAS DataBase Reference)
NIST Chemistry Reference
Vitamin a palmitate(79-81-2)
EPA Substance Registry System
Retinol, hexadecanoate(79-81-2)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,Xn,F
Risk Statements  63-53-61-11
Safety Statements  53-23-36/37/39-45-36/37-16-60
RIDADR  UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany  3
RTECS  VH6860000
HS Code  29362100
Toxicity LD50 (10 day) in mice, rats (mg/kg): 6060, 7910 orally (Kamm)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.

Vitamin A palmitate price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 46959-U Retinol palmitate analytical standard 79-81-2 u $25.3 2018-11-13 Buy
Sigma-Aldrich 1602502 Retinyl palmitate United States Pharmacopeia (USP) Reference Standard 79-81-2 4x50mg $348 2018-11-13 Buy
Alfa Aesar J63022 Vitamin A palmitate, 1.7 M.I.U./g 79-81-2 100g $137 2018-11-13 Buy
Alfa Aesar J63022 Vitamin A palmitate, 1.7 M.I.U./g 79-81-2 25g $50.5 2018-11-13 Buy
Cayman Chemical 23796 Retinyl Palmitate ≥95% 79-81-2 5g $49 2018-11-19 Buy

Vitamin A palmitate Chemical Properties,Uses,Production

Chemical Properties

95.0-100.5% Absorbance @325 nm ≥0.85%




all-trans-Retinyl Palmitate is an ester derivative of Retinol (R252000). all-trans-Retinyl Palmitate is used as a vitamin supplement in the treatment of Vitamin A deficiency. all-trans-Retinyl Palmita te is used as an antioxidant and a source of vitamin A added to low fat milk and other dairy products. all-trans-Retinyl Palmitate is also a constituent of some topically applied skin care products


retinyl palmitate is a skin conditioner. This retinoid is considered a milder version of retinoic acid, given its conversion properties. once on the skin, it converts to retinol, which in turn converts to retinoic acid. Physiologically, it is credited with increasing R epidermal thickness, stimulating the production of more epidermal protein, and increasing skin elasticity. Cosmetically, retinyl palmitate is used to reduce the number and depth of fine lines and wrinkles, and prevent skin roughness resulting from uV exposure. Secondary reactions such as erythema, dryness, or irritation are not associated with retinyl palmitate. It is even more effective when used in combination with glycolic acid because it achieves greater penetration. In the united States, its maximum usage level in cosmetic formulations is 2 percent. Retinyl palmitate is the ester of retinol and palmitic acid.


vitamin A palmitate is known as a skin “normalizer.” It acts as an antikeratinizing agent, helping the skin stay soft and plump, and improving its water-barrier properties. Because of its impact on the skin’s water-barrier properties, it is useful against dryness, heat, and pollution. It is also an anti-oxidant and is suggested for use in sunscreens. Clinical studies with vitamin A palmitate indicate a significant change in skin composition, with increases in collagen, DnA, skin thickness, and elasticity. Vitamin A palmitate’s stability is superior to retinol.

Safety Profile

Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

The palmitate is separated from retinol by column chromatography on water-deactivated alumina with hexane containing a very small percentage of acetone. It is also chromatographed on TLC silica gel G, using pet ether/isopropyl ether/acetic acid/water (180:20:2:5) or pet ether/acetonitrile/acetic acid/water (190:10:1:15) to develop the chromatogram. It is then recrystallised from propylene at low temperature (below -47o). [Beilstein 6 IV 4135.]

Vitamin A palmitate Preparation Products And Raw materials

Raw materials

Preparation Products

Vitamin A palmitate Suppliers

Global( 184)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Hebei Jiangkai Trading Co., Ltd
0086-17197824289/17197824028 CHINA 277 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 CHINA 894 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1664 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20229 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4558 58
Zhonglan Industry Co., Ltd.
(86) 531-82956570
(86) 531-82956571 CHINA 749 58

View Lastest Price from Vitamin A palmitate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-16 Vitamin A palmitate
US $7.00 / kg 1kg 99% 100kg career henan chemical co
2018-07-26 Retinol palmitate
US $15.00 / KG 1KG 99% 1000KG career henan chemical co
2018-01-10 Retinyl palmitat (vitamin A palmitate) skype : honestcooperation
US $1.00 / G 1G 99.7%min 500kg/day Hebei Jiangkai Trading Co., Ltd

Vitamin A palmitate Spectrum

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