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Vitamin A palmitate

Vitamin A palmitate
Vitamin A palmitate structure
CAS No.
79-81-2
Chemical Name:
Vitamin A palmitate
Synonyms
C02588;AROVIT;Optovit-A;Retinol Pro;Nanoactive A;BioActive VA;NanoActive VA;Retinylpalmitat;Soluble Vitamin A;RETINOL PALMITATE
CBNumber:
CB0406543
Molecular Formula:
C36H60O2
Formula Weight:
524.86
MOL File:
79-81-2.mol

Vitamin A palmitate Properties

Melting point:
28-29℃
Boiling point:
546.51°C (rough estimate)
Density 
0.9668 (rough estimate)
refractive index 
1.5250 (estimate)
Flash point:
194℃
storage temp. 
2-8°C
form 
oil
Specific Gravity
0.90~0.93 (20℃)
Water Solubility 
Soluble in chloroform, ether, and vegetable oils. Insoluble in water.
Merck 
13,10073
BRN 
1917366
InChIKey
VYGQUTWHTHXGQB-YFAKFODJSA-N
CAS DataBase Reference
79-81-2(CAS DataBase Reference)
FDA 21 CFR
582.5936; 310.545
Substances Added to Food (formerly EAFUS)
VITAMIN A PALMITATE
SCOGS (Select Committee on GRAS Substances)
Vitamin A palmitate
NCI Dictionary of Cancer Terms
retinyl palmitate
FDA UNII
1D1K0N0VVC
NIST Chemistry Reference
Vitamin a palmitate(79-81-2)
EPA Substance Registry System
Retinol, hexadecanoate (79-81-2)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08,GHS02,GHS07
Signal word  Danger
Hazard statements  H361-H360D-H413-H225-H319
Precautionary statements  P210-P280-P305+P351+P338-P337+P313-P403+P235-P202-P405-P501a-P201-P308+P313
Hazard Codes  T,Xn,F
Risk Statements  63-53-61-11
Safety Statements  53-23-36/37/39-45-36/37-16-60
RIDADR  UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany  3
RTECS  VH6860000
8-10-23
TSCA  Yes
HS Code  29362100
Toxicity LD50 (10 day) in mice, rats (mg/kg): 6060, 7910 orally (Kamm)

Vitamin A palmitate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 46959-U Retinol palmitate analytical standard 79-81-2 u $26.9 2020-08-18 Buy
Sigma-Aldrich 46959-U Retinol palmitate analytical standard 79-81-2 100 mg $27.8 2021-03-22 Buy
Sigma-Aldrich 1602502 Retinyl palmitate United States Pharmacopeia (USP) Reference Standard 79-81-2 4x50mg $371 2021-03-22 Buy
Alfa Aesar J63022 Vitamin A palmitate, 1.7 M.I.U./g 79-81-2 100g $171 2021-03-22 Buy
Alfa Aesar J63022 Vitamin A palmitate, 1.7 M.I.U./g 79-81-2 25g $60.6 2021-03-22 Buy

Vitamin A palmitate Chemical Properties,Uses,Production

Chemical Properties

95.0-100.5% Absorbance @325 nm ≥0.85%

Uses

antihypertensive

Uses

all-trans-Retinyl Palmitate is an ester derivative of Retinol (R252000). all-trans-Retinyl Palmitate is used as a vitamin supplement in the treatment of Vitamin A deficiency. all-trans-Retinyl Palmita te is used as an antioxidant and a source of vitamin A added to low fat milk and other dairy products. all-trans-Retinyl Palmitate is also a constituent of some topically applied skin care products

Uses

retinyl palmitate is a skin conditioner. This retinoid is considered a milder version of retinoic acid, given its conversion properties. once on the skin, it converts to retinol, which in turn converts to retinoic acid. Physiologically, it is credited with increasing R epidermal thickness, stimulating the production of more epidermal protein, and increasing skin elasticity. Cosmetically, retinyl palmitate is used to reduce the number and depth of fine lines and wrinkles, and prevent skin roughness resulting from uV exposure. Secondary reactions such as erythema, dryness, or irritation are not associated with retinyl palmitate. It is even more effective when used in combination with glycolic acid because it achieves greater penetration. In the united States, its maximum usage level in cosmetic formulations is 2 percent. Retinyl palmitate is the ester of retinol and palmitic acid.

Uses

vitamin A palmitate is known as a skin “normalizer.” It acts as an antikeratinizing agent, helping the skin stay soft and plump, and improving its water-barrier properties. Because of its impact on the skin’s water-barrier properties, it is useful against dryness, heat, and pollution. It is also an anti-oxidant and is suggested for use in sunscreens. Clinical studies with vitamin A palmitate indicate a significant change in skin composition, with increases in collagen, DnA, skin thickness, and elasticity. Vitamin A palmitate’s stability is superior to retinol.

Safety Profile

Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

The palmitate is separated from retinol by column chromatography on water-deactivated alumina with hexane containing a very small percentage of acetone. It is also chromatographed on TLC silica gel G, using pet ether/isopropyl ether/acetic acid/water (180:20:2:5) or pet ether/acetonitrile/acetic acid/water (190:10:1:15) to develop the chromatogram. It is then recrystallised from propylene at low temperature (below -47o). [Beilstein 6 IV 4135.]

Vitamin A palmitate Preparation Products And Raw materials

Raw materials

Preparation Products


Vitamin A palmitate Suppliers

Global( 298)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21022 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 3001 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29959 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2858 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5490 58
hdzhl biotechnology co., ltd
86-13032617415
sales@luchibiology.com CHINA 1275 58

View Lastest Price from Vitamin A palmitate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-21 Retinyl palmitate
79-81-2
US $10.00-99.00 / KG 0.5KG >99% 20tons Anhui Rencheng Technology Co., Ltd
2021-10-20 Vitamin A Palmitate
79-81-2
US $1.00 / Kg/Bag 50g 99 20 tons Wuhan wingroup Pharmaceutical Co., Ltd
2021-10-14 Vitamin A Palmitate;Retinol palmitate
79-81-2
US $200.00 / Kg/Bag 5KG 1000000-1700000 IU/g 500tons/month Hebei Dongdu Import and Export Co. LTD

Vitamin A palmitate Spectrum


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