Chloramphenicol sodium succinate
- CAS No.
- 982-57-0
- Chemical Name:
- Chloramphenicol sodium succinate
- Synonyms
- Nalecin;Mychel-S;Solnicol;Cloromoin;Nevimycin;Betamicetin;protophenicol;Clorofenicina;PubChem ID: 656580;Levomycetin-Nalcein
- CBNumber:
- CB0406947
- Molecular Formula:
- C15H15Cl2N2O8.Na
- Molecular Weight:
- 445.19
- MDL Number:
- MFCD00083598
- MOL File:
- 982-57-0.mol
| Melting point | >42oC (dec.) |
|---|---|
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | H2O: soluble50mg/mL |
| form | solid |
| color | White to Off-White |
| InChIKey | RPLOPBHEZLFENN-HTMVYDOJSA-M |
| CAS DataBase Reference | 982-57-0(CAS DataBase Reference) |
| FDA UNII | 872109HX6B |
| Proposition 65 List | Chloramphenicol Sodium Succinate |
| EPA Substance Registry System | Chloramphenicol sodium succinate (982-57-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H351 |
| Precautionary statements | P202-P264-P270-P280-P301+P312-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 40 |
| Safety Statements | 22-36 |
| WGK Germany | 3 |
| RTECS | AB6905000 |
Chloramphenicol sodium succinate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C3787 | Chloramphenicol succinate sodium salt ≥80% (HPLC) | 982-57-0 | 5g | $73.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | C3787 | Chloramphenicol succinate sodium salt ≥80% (HPLC) | 982-57-0 | 25g | $295 | 2024-03-01 | Buy |
| Sigma-Aldrich | C1425000 | Chloramphenicol sodium succinate European Pharmacopoeia (EP) Reference Standard | 982-57-0 | c1425000 | $90 | 2024-03-01 | Buy |
| Sigma-Aldrich | C3787 | Chloramphenicol succinate sodium salt ≥80% (HPLC) | 982-57-0 | 100g | $730 | 2023-06-20 | Buy |
| TRC | C325065 | ChloramphenicolSuccinateSodium | 982-57-0 | 25g | $140 | 2021-12-16 | Buy |
Chloramphenicol sodium succinate Chemical Properties,Uses,Production
Chemical Properties
White or yellowish-white powder, hygroscopic
Uses
antibacterial, antirickettsial, inhibits protein synthesis
Uses
Chloramphenicol Succinate Sodium is a derivative of Chloramphenicol (C325030) which are broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
Uses
Chloramphenicol succinate sodium is the salt prepared from chloramphenicol succinate using the free carboxylic acid of the succinate which ionises and readily forms in weakly sodium hydroxide solutions. The sodium salt is the preferred formulation for pharmaceutical applications, providing a more readily soluble product. Chloramphenicol succinate is significantly less active than chloramphenicol but acts as a prodrug, forming chloramphenicol in the presence of succinate dehydrogenase.
General Description
White powder.
General Description
Chloramphenicol sodium succinate is the water-solublesodium salt of the hemisuccinate ester of chloramphenicol.Because of the low solubility of chloramphenicol, the sodiumsuccinate is preferred for intravenous administration. Theavailability of chloramphenicol from the ester followingintravenous administration is estimated to be 70% to 75%; theremainder is excreted unchanged. Poor availability ofthe active form from the ester following intramuscular injectionprecludes attaining effective plasma levels of the antibioticby this route. Orally administered chloramphenicol orits palmitate ester actually gives higher plasma levels of theactive antibiotic than does intravenously administered chloramphenicolsodium succinate. Nonetheless, effectiveconcentrations are achieved by either route.
Air & Water Reactions
Freely soluble in water.
Fire Hazard
Flash point data for Chloramphenicol sodium succinate are not available, but Chloramphenicol sodium succinate is probably combustible.
Chloramphenicol sodium succinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5985 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
View Lastest Price from Chloramphenicol sodium succinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-09-29 | Chloramphenicol sodium succinate
982-57-0
|
US $0.00 / KG | 1KG | 98.0% | 500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-08-12 | Chloramphenicol sodium succinate
982-57-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-12-26 | Chloramphenicol sodium succinate
982-57-0
|
US $6.60 / KG | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- Chloramphenicol sodium succinate
982-57-0
- US $0.00 / KG
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Chloramphenicol sodium succinate
982-57-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Chloramphenicol sodium succinate
982-57-0
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co