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Sancycline
- CAS No.
- 808-26-4
- Chemical Name:
- Sancycline
- Synonyms
- Sancycline Hydrochloride;(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide;CS-676;GS 2147;Bonomycin;NSC-51812;Norcycline;SANCYCLINE;Sancyclinum;808-26-4 Sancycline
- CBNumber:
- CB0420370
- Molecular Formula:
- C21H22N2O7
- Molecular Weight:
- 414.41
- MDL Number:
- MFCD00864992
- MOL File:
- 808-26-4.mol
Last updated:2024-03-27 13:45:20
| Melting point | 224-2280C (dec) |
|---|---|
| Boiling point | 750.9±60.0 °C(Predicted) |
| Density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.50±1.00(Predicted) |
| color | Beige to Dark Beige |
| Stability | Hygroscopic |
| CAS DataBase Reference | 808-26-4 |
| FDA UNII | ODN00F2SJG |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H362 | |||||||||
| Precautionary statements | P201-P260-P263-P264-P270-P308+P313 | |||||||||
| NFPA 704 |
|
Sancycline price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PH000287 | (4S,4AS,5AR,12AS)-4-(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-2-NAPHTHACENECARBOXAMIDE AldrichCPR | 808-26-4 | 1MG | $172 | 2023-06-20 | Buy |
| Cayman Chemical | 23100 | Sancycline ≥98% | 808-26-4 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 23100 | Sancycline ≥98% | 808-26-4 | 25mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 23100 | Sancycline ≥98% | 808-26-4 | 100mg | $365 | 2024-03-01 | Buy |
| Cayman Chemical | 23100 | Sancycline ≥98% | 808-26-4 | 250mg | $606 | 2024-03-01 | Buy |
Sancycline Chemical Properties,Uses,Production
Description
Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 μg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 μg/ml. In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.
Chemical Properties
Yellow Solid
Uses
Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
Uses
A semi-synthetic antibiotic related to tetracycline
Uses
Sancycline is a tetracycline bacteriostatic antibiotic which also binds to the Tet repressor protein (TetR).
Definition
ChEBI: Sancycline is a member of tetracyclines.
brand name
Bonomycin (Pfizer).
Sancycline Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 182)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from Sancycline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-10 | Minocycline EP Impurity B
808-26-4
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC | |
 |
2024-03-27 | Sancycline
808-26-4
|
US $2500.00 / g | 1g | 98 | 5 Kg | R&D Scientific Inc. | |
 |
2021-06-09 | Sancycline
808-26-4
|
US $0.00 / Kg/Bag | 1Kg/Bag | 99% | 20T | Shenzhen Shengda Pharma Limited |
-
- Minocycline EP Impurity B
808-26-4
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
-
- Sancycline
808-26-4
- US $2500.00 / g
- 98
- R&D Scientific Inc.
-
- Sancycline
808-26-4
- US $0.00 / Kg/Bag
- 99%
- Shenzhen Shengda Pharma Limited
SANCYCLINE
(4S,4aS,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1-11-dioxo-2-naphthacenecarboxamide
6-Demethyl-6-deoxytetracycline
Bonomycin
GS 2147
Norcycline
(4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide
NSC-51812
Minocycline IMpurity B
2-NaphthacenecarboxaMide,4-(diMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4S,4aS,5aR,12aS)-
6-DeMethyl-6-deoxytetracycline, BonoMycin, Norcycline
BONOMYCIN; NORCYCLINE;6-DEMETHYL-6-DEOXYTETRACYCLINE
Minocycline EP Impurity B/Sancycline/(4S,5aS,8Z,10E,14aS)-4-(dimethylamino)-3,11,14,14a-tetrahydroxy-1,13-dioxo-1,4,4a,5,5a,6,7,12,13,14a-decahydrocyclodeca[b]naphthalene-2-carboxamide
CS-676
Sancycline in stock Factory
Sancycline (Bonomycin
Sancyclinum
Minocycline EP Impurity B (Sancycline)
SancyclineQ: What is
Sancycline Q: What is the CAS Number of
Sancycline Q: What is the storage condition of
Sancycline Q: What are the applications of
Sancycline
808-26-4 Sancycline
Sancycline Hydrochloride
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
808-26-4
208538-73-6
C21H22N2O7
C21H23ClN2O7
Intermediates & Fine Chemicals
Pharmaceuticals