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FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE

CAS No.
1013883-02-7
Chemical Name:
FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE
Synonyms
Fmoc-phe(2-Ae-Boc)-OH;Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH;Fmoc-4-[2-(Boc-amino)ethoxy]-phenylalanine;FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE;N-Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine;(9H-Fluoren-9-yl)MethOxy]Carbonyl 4-[2-((Tert-Butoxy)Carbonyl amino)ethoxy]-L-Phenylalanine;O-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine;L-Tyrosine, O-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-((tert-butoxycarbonyl)amino)ethoxy)phenyl)propanoic acid;(2S)-3-[4-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CBNumber:
CB0432276
Molecular Formula:
C31H34N2O7
Molecular Weight:
546.61
MDL Number:
MFCD07781260
MOL File:
Mol file
Last updated:2023-05-04 15:15:58

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Properties

Boiling point 759.1±60.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
pka 2.96±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS05
Signal word  Danger
Hazard statements  H315-H335-H318
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310
HazardClass  IRRITANT

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 0346AP Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH 1013883-02-7 100mg $171 2021-12-16 Buy
Matrix Scientific 041971 Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine 1013883-02-7 250mg $212 2021-12-16 Buy
AK Scientific 0346AP Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH 1013883-02-7 250mg $293 2021-12-16 Buy
Activate Scientific AS101022 Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine 95% ee 1013883-02-7 1g $412 2021-12-16 Buy
ChemPep 183011 Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH 1013883-02-7 1g $500 2021-12-16 Buy
Product number Packaging Price Buy
0346AP 100mg $171 Buy
041971 250mg $212 Buy
0346AP 250mg $293 Buy
AS101022 1g $412 Buy
183011 1g $500 Buy

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Chemical Properties,Uses,Production

Uses

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

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Add O-[2-[[tert-butoxycarbonyl]amino]ethyl]-L-tyrosine (3.24g, 10mmol) in a 100mL three-necked flask equipped with magnetic stirring and a thermometer, with a mass concentration of 5 · 5% 21.2g of sodium carbonate aqueous solution, 20mL of 9-fluorenylmethyl-N-succinimidyl carbonate (3.37g, 10mmol) in tetrahydrofuran solution was added dropwise at room temperature, after the addition, the amidation reaction was carried out at room temperature, monitored by TLC To the end of the reaction. Concentrated to remove part of the solvent, acidified with 2N hydrochloric acid to pH 6~7, extracted with ethyl acetate, washed with saturated brine, concentrated, beaten with petroleum ether, filtered and dried to obtain a white solid O-alkyl-N-[ Fluorenylmethyloxycarbonyl]-L-tyrosine is 4.68g, the yield is 85.7%, the HPLC purity is 99.8%, and the ee value is 99.8%.

FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338 stella@zetchem.com China 2141 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10297 58
Chengdu Aslee Biopharmaceuticals, Inc.
28-85305008 CHINA 964 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
GL Biochem (Shanghai) Ltd.
+86-021-61263370 +86-18901917034 CHINA 3904 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
FMOC-4-[2-(BOC-AMINO)ETHOXY]-L-PHENYLALANINE Fmoc-4-[2-(Boc-amino)ethoxy]-Phe-OH N-Fmoc-4-[2-(Boc-amino)ethoxy]-L-phenylalanine O-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine Fmoc-4-[2-(Boc-amino)ethoxy]-phenylalanine (9H-Fluoren-9-yl)MethOxy]Carbonyl 4-[2-((Tert-Butoxy)Carbonyl amino)ethoxy]-L-Phenylalanine Fmoc-phe(2-Ae-Boc)-OH (2S)-3-[4-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid L-Tyrosine, O-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-((tert-butoxycarbonyl)amino)ethoxy)phenyl)propanoic acid 1013883-02-7 peptide