ChemicalBook
Chinese Japanese Germany

L-Carnosine

Description Reference
L-Carnosine
L-Carnosine
CAS No.
305-84-0
Chemical Name:
L-Carnosine
Synonyms
n-2-m;karnozzn;ignotine;Carnosin;Karnozin;BETA-A-H;Dragosine;CARNOSINE;L-IGNOTINE;L-CARNOSINE
CBNumber:
CB0433763
Molecular Formula:
C9H14N4O3
Formula Weight:
226.23
MOL File:
305-84-0.mol

L-Carnosine Properties

Melting point:
253 °C (dec.)(lit.)
alpha 
20.9 º (c=1.5, H2O)
Boiling point:
367.84°C (rough estimate)
Density 
1.2673 (rough estimate)
refractive index 
21 ° (C=2, H2O)
storage temp. 
2-8°C
form 
crystalline
pka
2.62(at 25℃)
color 
White
Water Solubility 
almost transparency
Merck 
14,1850
BRN 
87671
Stability:
Stable, but may be heat sensitive - store cold. Incompatible with strong oxidizing agents.
InChIKey
CQOVPNPJLQNMDC-ZETCQYMHSA-N
CAS DataBase Reference
305-84-0(CAS DataBase Reference)
EPA Substance Registry System
L-Histidine, .beta.-alanyl-(305-84-0)

SAFETY

Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  2
RTECS  MS3080000
3-10
TSCA  Yes
HS Code  29332900

L-Carnosine price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C9625 L-Carnosine ~99%, crystalline 305-84-0 5g $98.3 2018-11-13 Buy
Sigma-Aldrich C9625 L-Carnosine ~99%, crystalline 305-84-0 10mg $19.5 2018-11-13 Buy
TCI Chemical A0222 beta-Alanyl-L-histidine >98.0%(HPLC)(T) 305-84-0 1g $25 2018-11-22 Buy
TCI Chemical A0222 beta-Alanyl-L-histidine >98.0%(HPLC)(T) 305-84-0 5g $72 2018-11-22 Buy
Alfa Aesar H65668 beta-Alanyl-L-histidine, 95% 305-84-0 5g $43.3 2018-11-13 Buy

L-Carnosine Chemical Properties,Uses,Production

Description

Carnosine is a dipeptide comprising beta-alanine and histidine. It is found in muscular and other tissues. It has strong oxidant property as it can scavenge both reactive oxygen species (ROS) and reactive nitrogen species (RNS). Carnosine acts as a cytosolic buffering agent and as a regulator of macrophage function.1 Attributing to its ability to form complexes with transition metals, it is used to regulate the content of transition metal ions in biological fluids and tissues.
Carnosine can prevent aging and can be used to prevent or treat complications of diabetes such as nerve damage, eye disorders (cataracts), and kidney problems.2 Potential therapeutic actions of carnosine include antihypertensive effects, immunomodulation, would healing, and antitumor/chemopreventive effects. The chelate compound of zinc ion and carnosine has been used in Japan for gastritis, gastric ulcers, and dyspepsia symptoms.3

Reference

  1. P. J. Quinn, A. A. Boldyrev, V. E. Formazuyk, Carnosine: Its properties, functions and potential therapeutic applications, Molecular Aspects of Medicine, 1992, vol. 13, pp. 379-444
  2. https://www.webmd.com/vitamins/ai/ingredientmono-1038/carnosine
  3. G. M. Halpern, Zinc-Carnosine: Nature’s Safe and Effective Remedy for Ulcers, 2005, ISBN-10 0757002749

Chemical Properties

Crystalline

Uses

antioxidant, antisenescense, antineoplastic

Uses

L-Carnosine is a naturally-occurring histidine-containing compound and the biological role of this dipeptide is to act as cytosolic buffering agents. Other roles ascribed to L-Carnosine include action s as neurotransmitters, modulation of enzymic activities and chelation of heavy metals.

Uses

carnosine is an anti-oxidant that works to prevent cellular damage because of free radical activity. Studies indicate an ability to boost the immunological functions. Carnosine is a naturally occurring amino acid. In cosmetics, it has anti-aging and skin-conditioning applications.

Definition

ChEBI: A dipeptide that is the N-(beta-alanyl) derivative of L-histidine.

Safety Profile

Mildly toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Likely impurities are histidine and β-alanine. Crystallise L-carnosine from water by adding EtOH in excess. Recrystallise it from aqueous EtOH by slow addition of EtOH to a strong aqueous solution of the dipeptide. Its solubility in H2O is 33.3% at 25o. [Vinick & Jung J Org Chem 48 392 1983, Turner J Am Chem Soc 75 2388 1953, Sifford & du Vigneaud J Biol Chem 108 753 1935, Beilstein 25 H 516, 25 I 717, 25 II 408.]

L-Carnosine Preparation Products And Raw materials

Raw materials

Preparation Products


L-Carnosine Suppliers

Global( 318)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Kono Chem Co., Ltd
+86-132 8924 6953
info@konochemical.com CHINA 2164 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 894 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14293 60
AB PharmaTech,LLC
323-480-4688
323-480-4688 sales01@abpharmatechusa.com United States 991 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1659 55
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4529 58
Zhonglan Industry Co., Ltd.
(86) 531-82956570
(86) 531-82956571 sales@zhonglanindustry.com CHINA 749 58

View Lastest Price from L-Carnosine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-27 L-Carnosine
305-84-0
US $100.00 / KG 1KG 99% Customized career henan chemical co
2018-07-25 L-Carnosine
305-84-0
US $15.00 / KG 1KG 99% 1000KG career henan chemical co

L-Carnosine Spectrum


305-84-0(L-Carnosine)Related Search:


  • beta-Alanyl-histidine
  • ignotine
  • karnozzn
  • n-2-m
  • Nalpha-(beta-alanyl)-L-histidine
  • n-beta-alanyl-l-histidin
  • L-Carnosine Vetec(TM) reagent grade, 98%
  • L-Histidine,beta-alanyl-
  • L-Carnosine (beta-Alanyl-L-histidine)
  • β-Ala-His-OH
  • L-Carnosine,N-beta-Alanyl-L-histidine
  • Polaprezinc Impurity 6
  • Dragosine
  • (2S)-2-(3-Aminopropanamido)-3-(4H-imidazol-4-yl)propanoicacid
  • β-Alanyl-L-histidine
  • Beta-Alanyl-L-Hystidine
  • L-CARNOSINE CRYSTALLINE
  • L-Carnosine(H-b-Ala-His-Oh)
  • N-β-Alanyl-L-histidine
  • (2S)-2-(3-aminopropanoylamino)-3-(3H-imidazol-4-yl)propanoic acid
  • L-HISTIDINE,N-BETA-ALANYL
  • H-BETA-ALA-HIS-OH
  • L-IGNOTINE
  • L-BETA-ALANINE HISTIDINE
  • L-CARNOSINE
  • B-ALANYL-L-HISTIDINE
  • BETA-A-H
  • BETA-ALANYL-L-HISTIDINE
  • BETA-ALA-L-HIS
  • BETA-ALA-HIS
  • CARNOSINE
  • CARNOSINE, L-
  • N-B-ALANYL-L-HISTIDINE
  • N-BETA-ALANYL-L-HISTIDINE
  • Carnosin
  • H-SS-ALA-HIS-OH (L-CARNOSINE)
  • L-B-ALANINE HISTIDINE
  • L-CARNITINEOROTIC
  • H-SS-ALA-HIS-OH
  • H-b-Ala-His-OH
  • Karnozin
  • β-Ala-L-His-OH
  • L-Carnosine,98%
  • H-Beta-Ala-His-OH(L-Carnosine)
  • L-Carnosine L-Ignotine
  • -
  • 305-84-0
  • BioChemical
  • Amino Acid Library
  • Biochemicals and Reagents
  • Carnosinase
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Substrates
  • Metabolomics
  • Metabolic Libraries
  • Substrates by Enzyme
  • 22-401-4
  • C9H14N4O3
Copyright 2017 © ChemicalBook. All rights reserved