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Dyclonine hydrochloride

Description References
Dyclonine hydrochloride
Dyclonine hydrochloride structure
CAS No.
536-43-6
Chemical Name:
Dyclonine hydrochloride
Synonyms
s154;c5422;p-267;diclonia;tanaclone;DYCLONINE;dyclothane;dyclocainum;DYCLONINE HCL;dyclonehydrochloride
CBNumber:
CB0439886
Molecular Formula:
C18H28ClNO2
Formula Weight:
325.87
MOL File:
536-43-6.mol

Dyclonine hydrochloride Properties

Melting point:
175-176°C
storage temp. 
-20°C Freezer
Water Solubility 
Partly soluble in water. Soluble in chloroform, ethanol, acetone and methanol.
Merck 
14,3473
InChIKey
KNZADIMHVBBPOA-UHFFFAOYSA-N
CAS DataBase Reference
536-43-6(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  26-36
RIDADR  3249
WGK Germany  3
RTECS  UG8750000
HazardClass  6.1(b)
PackingGroup  III
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Dyclonine hydrochloride price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1849 Dyclonine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 536-43-6 500mg $87.5 2018-11-20 Buy
Sigma-Aldrich 1230000 Dyclonine hydrochloride United States Pharmacopeia (USP) Reference Standard 536-43-6 200mg $352.8 2018-11-20 Buy
TCI Chemical D4303 Dyclonine Hydrochloride >98.0%(HPLC)(T) 536-43-6 5g $88 2018-11-22 Buy
TCI Chemical D4303 Dyclonine Hydrochloride >98.0%(HPLC)(T) 536-43-6 25g $263 2018-11-22 Buy
Alfa Aesar J61330 Dyclonine hydrochloride 536-43-6 5g $75.9 2018-11-20 Buy

Dyclonine hydrochloride Chemical Properties,Uses,Production

Description

Dyclonine hydrochloride is the hydrochloride salt of Dyclonine. Dyclonine belongs to a kind of oral anaesthetic. It is contained in the “Sucrets” as well as some kinds of Cepacol sore throat spray as an active ingredient. Dyclonine takes effect through reversibly binding to the activated sodium channels located on the neuronal membrane. This decreases the permeability of sodium across the neuronal membrane, further increasing the threshold for excitation. Overall, Dyclonine stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and further suppressing the subsequent conduction. This causes a transient and reversible anaesthetic effect in a local area of the body.

References

https://en.wikipedia.org/wiki/Dyclonine
https://pubchem.ncbi.nlm.nih.gov/compound/Dyclonine_hydrochloride#section=Top

Chemical Properties

White Crystalline Solid

Uses

anesthetic (topical)

Uses

Used as a local anesthetic

Definition

ChEBI: The hydrochloride salt of dyclonine.

brand name

Dyclone (AstraZeneca).

Dyclonine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Dyclonine hydrochloride Suppliers

Global( 195)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 500 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 663 60
Meihua Biological Technology Co.,Ltd
15175972705
031145896235 sales@hbmeihua.cn CHINA 215 58
Jinan Jianfeng Chemical Co., Ltd
15562555968
info@pharmachemm.com CHINA 617 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58

View Lastest Price from Dyclonine hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Dyclonine hydrochloride
536-43-6
US $1.00 / KG 1G 98% 100KG career henan chemical co
2019-03-06 Dyclonine hydrochloride cas536-43-6 (whatsapp:+8618830163278)
536-43-6
US $500.00 / kg 1kg 99% 100 Hebei Huanhao Biotechnology Co., Ltd.
2019-02-13 Dyclonine hydrochloride cas 536-43-6 (whatsapp:+8618830163278)
536-43-6
US $120.00 / kg 1kg 99.7% 20tons Hebei Huanhao Biotechnology Co., Ltd.

Dyclonine hydrochloride Spectrum


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