Riluzole hydrochloride
- CAS No.
- 850608-87-6
- Chemical Name:
- Riluzole hydrochloride
- Synonyms
- RILUZOLE HCL;RILUZOLE HYDROCHLORIDE;2-AMINO-6-TRIFLUOROMETHOXYBENZOTHIAZOLE HYDROCHLORIDE;6-(Trifluoromethoxy)benzo[d]thiazol-2-amine hydrochloride
- CBNumber:
- CB0442491
- Molecular Formula:
- C8H6ClF3N2OS
- Molecular Weight:
- 270.66
- MDL Number:
- MFCD02262214
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
Riluzole hydrochloride price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14577 | Riluzole (hydrochloride) ≥99% | 850608-87-6 | 10mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 14577 | Riluzole (hydrochloride) ≥99% | 850608-87-6 | 50mg | $169 | 2024-03-01 | Buy |
| Tocris | 0768 | Riluzolehydrochloride ≥98%(HPLC) | 850608-87-6 | 25 | $106 | 2021-12-16 | Buy |
| Usbiological | 256455 | Riluzole hydrochloride | 850608-87-6 | 25mg | $353 | 2021-12-16 | Buy |
| TRC | R510030 | RiluzoleHydrochloride | 850608-87-6 | 250mg | $580 | 2021-12-16 | Buy |
Riluzole hydrochloride Chemical Properties,Uses,Production
Description
Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Formulations containing riluzole have been explored as therapeutics for slowing disease progression of amyotrophic lateral sclerosis.
Uses
Riluzole is a glutamate release inhibitor. It also induces caspase-dependent apoptosis and suppress cell proliferation in human heptocellular carcinoma. Riluzole is a neuroprotective and a anticancer agent.
Uses
Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg. Riluzole has been explored as a therapeutic for slowing disease progression of amyotrophic lateral sclerosis.
storage
Room temperature
Riluzole hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Riluzole hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3420 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3444 | 55 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9288 | 58 |
| Aikon International Limited | 025-66113011 18112977050 | cb6@aikonchem.com | China | 15495 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |