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N-Cbz-L-Leucine

CAS No.
2018-66-8
Chemical Name:
N-Cbz-L-Leucine
Synonyms
Z-LEU;Z-LEU-OH;Z-LEUCINE;Z-L-LEU-OH;CBZ-LEU-OH;Z-L-LEUCINE;CBZ-LEUCINE;Z-Leu-OH 97%;CBZ-L-LEU-OH;CBZ-L-LEUCINE
CBNumber:
CB0449278
Molecular Formula:
C14H19NO4
Molecular Weight:
265.3
MDL Number:
MFCD00026494
MOL File:
2018-66-8.mol
MSDS File:
SDS
Last updated:2023-12-18 14:20:06

N-Cbz-L-Leucine Properties

alpha -17 º (c=2, ethanol)
Boiling point 408.52°C (rough estimate)
Density 1 g/mL at 25 °C(lit.)
refractive index n20/D 1.512(lit.)
Flash point 85 °F
storage temp. Sealed in dry,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form viscous liquid
pka 4.00±0.21(Predicted)
Specific Gravity 1.0
color Colorless to Light yellow
optical activity [α]20/D 17°, c = 2 in ethanol
Water Solubility Not miscible or difficult to mix in water. Soluble in chloroform, DMSO and methanol.
BRN 1253861
CAS DataBase Reference 2018-66-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS08
Signal word  Warning
Hazard statements  H226-H351-H361d
Precautionary statements  P210-P280-P370+P378
Hazard Codes  Xn
Risk Statements  10-20/22-37/38-40-41-36/37/38-20/21/22-67-63-19
Safety Statements  16-26-36/37/39-45-36-36/37-60
RIDADR  UN 1993 3/PG 3
WGK Germany  3
RTECS  OH2921000
HS Code  29242990
NFPA 704
1
2 0

N-Cbz-L-Leucine price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 521221 Z-Leu-OH 97% (HPLC) 2018-66-8 25ml $108 2023-01-07 Buy
TCI Chemical C0739 N-Carbobenzoxy-L-leucine >96.0%(T) 2018-66-8 5g $43 2024-03-01 Buy
TCI Chemical C0739 N-Carbobenzoxy-L-leucine >96.0%(T) 2018-66-8 25g $123 2024-03-01 Buy
Alfa Aesar L08471 N-Benzyloxycarbonyl-L-leucine, 98% (dry wt.), may cont. up to ca 5% solvent 2018-66-8 5g $26.6 2023-06-20 Buy
Alfa Aesar L08471 N-Benzyloxycarbonyl-L-leucine, 98% (dry wt.), may cont. up to ca 5% solvent 2018-66-8 25g $76.6 2021-12-16 Buy
Product number Packaging Price Buy
521221 25ml $108 Buy
C0739 5g $43 Buy
C0739 25g $123 Buy
L08471 5g $26.6 Buy
L08471 25g $76.6 Buy

N-Cbz-L-Leucine Chemical Properties,Uses,Production

Chemical Properties

yellow oil or weak solid

Uses

Reactant for:

  • Peptide-based preparation of potential antitumor agents
  • Preparation of cyclopropyl peptidomimetics
  • Peptide synthesis

Definition

ChEBI: A L-leucine derivative obtained by the substitution of a benzyloxycarbonyl group on the nitrogen atom.

51021-87-5
2018-66-8
Synthesis of N-Cbz-L-Leucine from Z-LEU-OME
Global( 368)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8618980456393 daisy@enlaibio.com China 1369 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58

View Lastest Price from N-Cbz-L-Leucine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cbz-L-Leu-OH pictures 2024-04-18 Cbz-L-Leu-OH
2018-66-8
US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
N-Cbz-L-Leucine pictures 2021-08-12 N-Cbz-L-Leucine
2018-66-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
N-Cbz-L-Leucine pictures 2019-07-06 N-Cbz-L-Leucine
2018-66-8
US $1.00 / KG 1KG 99% 20kg Career Henan Chemical Co
  • Cbz-L-Leu-OH pictures
  • Cbz-L-Leu-OH
    2018-66-8
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • N-Cbz-L-Leucine pictures
  • N-Cbz-L-Leucine
    2018-66-8
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
N-Benzyloxycarbonyl-L-leucine, 98+% Z-L-LEUCINE extrapure N-Carbobenzyloxy-L-leucine, N-Cbz-L-leucine, Z-L-Leucine L-(Carbobenzyloxy)leucine L-Leucine, N-[(phenylmethoxy)carbonyl]- L-N-(Benzyloxycarbonyl)leucine N-Carboxy-L-leucine N-benzyl ester (2S)-2-(Benzyloxycarbonylamino)-4-methylpentanoic acid N-Cbz-L-leucine Z-Leu-OH N-Carbobenzyloxy-L-leucine,95% (S)-2-(((benzyloxy)carbonyl)aMino)-4-Methylpentanoic acid Z-Leu-OH 97% (S)-Z-2-amino-4-methylpentanoic acid Z-L-leucine≥ 98% (HPLC) N-ALPHA-BENZYLOXYCARBONYL-L-LEUCINE N-CARBOBENZOXY-L-LEUCINE N-BENZYLOXYCARBONYL-L-LEUCINE N-ALPHA-CBZ-L-LEUCINE N-ALPHA-CARBOBENZOXY-L-LEUCINE N-CARBOBENZYLOXY-L-LEUCINE N-CBZ-L-LEUCINE N-CBZ-L-LEUCINE-OH Z-L-LEUCINE Z-L-LEU-OH Z-LEU-OH Z-LEUCINE benzyloxycarbonylleucine carbobenzoxyleucine carbobenzoxy-l-leucine carbobenzyloxy-l-leucine BENZYLOXYCARBONYL-L-LEUCINE CBZ-L-LEU-OH CBZ-L-LEUCINE CBZ-LEUCINE CBZ-LEU-OH l-n-carboxyleucinen-benzylester Z-LEU N-alpha-Benzyloxycarbonyl-L-leucine (oil) Z-L-LEUCINE LIQUID N-Benzyloxycarbonyl-L-leucine, 98+%(dry wt.), may cont. up to ca 5% solvent n-((phenylmethoxy)carbonyl)-l-leucin n-((phenylmethoxy)carbonyl)-l-leucine n-benzyloxycarbonylleucine n-carboxy-,n-benzylester,l-leucin Z-Leu-OH (Syrup) N-Carbobenzoxy-L-leucine > N-Carbobenzoxy-L N-Cbz-L-Leucine USP/EP/BP N-Cbz-L-leucine, 97% [Z-Leu-OH] 2018-66-8 2018-66-6 CH32CHCH2CHNHCOOCH2C6H5COOH Amino Acid Derivatives Peptide Synthesis Leucine Specialty Synthesis CARBOXYLIC ACID Protected & Labeled Amino Acids