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Isopropyl palmitate

Isopropyl palmitate
Isopropyl palmitate structure
CAS No.
142-91-6
Chemical Name:
Isopropyl palmitate
Synonyms
Deltyl;Isopal;Isopalm;Emcol-IP;estol103;ja-faipp;usafke-5;kesscoipp;Lexol IPP;nikkolipp
CBNumber:
CB0451826
Molecular Formula:
C19H38O2
Formula Weight:
298.5
MOL File:
142-91-6.mol

Isopropyl palmitate Properties

Melting point:
11-13 °C (lit.)
Boiling point:
160°C 2mm
Density 
0.852 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.438(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
<0.001g/l
form 
neat
Water Solubility 
Not miscible or difficult to mix with water.
BRN 
1786567
InChIKey
XUGNVMKQXJXZCD-UHFFFAOYSA-N
Substances Added to Food (formerly EAFUS)
ISOPROPYL PALMITATE
FDA 21 CFR
310.545
CAS DataBase Reference
142-91-6(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
8CRQ2TH63M
NIST Chemistry Reference
Isopropyl palmitate(142-91-6)
EPA Substance Registry System
Isopropyl palmitate (142-91-6)
Cosmetics Info
Isopropyl Palmitate
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Hazard statements  H315-H319
Precautionary statements  P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36
WGK Germany  -
RTECS  RT4900000
TSCA  Yes
HS Code  29157090

Isopropyl palmitate price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W515604 Isopropyl Palmitate ≥90% 142-91-6 1 SAMPLE $50 2021-12-16 Buy
Sigma-Aldrich 291781 Isopropyl palmitate technical grade, 90% 142-91-6 1l $66.6 2021-12-16 Buy
Sigma-Aldrich I0725000 Isopropyl hexadecanoate European Pharmacopoeia (EP) Reference Standard 142-91-6 $190 2021-12-16 Buy
Sigma-Aldrich 1350603 Isopropyl palmitate United States Pharmacopeia (USP) Reference Standard 142-91-6 500mg $399 2021-12-16 Buy
TCI Chemical P0005 Isopropyl Palmitate >97.0%(GC) 142-91-6 25mL $17 2021-12-16 Buy

Isopropyl palmitate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless liquid

Chemical Properties

Isopropyl palmitate is a clear, colorless to pale yellow-colored, practically odorless viscous liquid that solidifies at less than 16°C.

Uses

Pharmaceutic aid (vehicle, oleaginous).

Uses

isopropyl palmitate is an emollient and moisturizer, it also acts as a binder and solvent. Similar to isopropyl myristate, it is produced from the combination of palmitic acid (coconut or palm oil) and isopropyl alcohol. enzymes are able to metabolize this ingredient and studies do not show allergic reactions or toxicity. Some sources indicate comedogenicity potential.

Uses

Isopropyl palmitate is used to formulate and evaluate the suitability of pluronic lecithin organogels containing flurbiprofen for topical application and to characterize microemulsion systems of isopropyl palmitate, water and 2:1 Brij 97, and 1-butanol by different experimental techniques.

Definition

ChEBI: A fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol. Metabolite observed in cancer metabolism.

Production Methods

Isopropyl palmitate is prepared by the reaction of palmitic acid with propan-2-ol in the presence of an acid catalyst. A high-purity material is also commercially available, which is produced by enzymatic esterification at low temperatures.

General Description

Isopropyl palmitate is an analog of isopropyl myristate and an aliphatic ester used as a flavoring ingredient in food industry. It is one of the volatile compounds found in Psidium salutare fruits and boiled buckwheat flour.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical Applications

Isopropyl palmitate is a nongreasy emollient with good spreading characteristics, used in topical pharmaceutical formulations and cosmetics such as: bath oils; creams; lotions; make-up; hair care products; deodorants; lip products; suntan preparations; and pressed powders.
Isopropyl palmitate is an established penetration enhancer for transdermal systems. It has also been used in controlled-release percutaneous films. Table I: Uses of isopropyl palmitate

Safety

Isopropyl palmitate is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a relatively nontoxic and nonirritant material.
LD50 (mouse, IP): 0.1 g/kg

storage

Isopropyl palmitate is resistant to oxidation and hydrolysis, and does not become rancid. It should be stored in a well-closed container, above 16°C, and protected from light.

Regulatory Status

Included in the FDA Inactive Ingredients Database (topical and transdermal preparations). Used in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Isopropyl palmitate Preparation Products And Raw materials

Raw materials

Preparation Products


Isopropyl palmitate Suppliers

Global( 309)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9134 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2940 58
GIHI CHEMICALS CO.,LIMITED
08657186217390
sales@gihichemicals.com CHINA 310 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5942 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4000 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Henan Xiangtong Chemical Co., Ltd.
86-371-61312303
86-371-86017988 cathy@hnxtchem.com CHINA 293 58

View Lastest Price from Isopropyl palmitate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-01 Isopropyl palmitate
142-91-6
US $10.00 / KG 1KG 99.% 10 ton Hebei Crovell Biotech Co Ltd
2021-11-30 Isopropyl palmitate
142-91-6
US $13.50 / KG 25KG 98% 1-30mt Baoji Guokang Bio-Technology Co., Ltd.
2021-10-28 Isopropyl Palmitate IPP
142-91-6
US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd

Isopropyl palmitate Spectrum


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