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(4-Fluorophenyl)acetone

CAS No.
459-03-0
Chemical Name:
(4-Fluorophenyl)acetone
Synonyms
cas 459-03-0;2-Propanone, 1-(4;4-FLUOROPHENYLACETONE;4'-FLUOROPHENYLACETONE;(P-FLUOROPHENYL)ACETONE;4-Fluorophenylacetone98%;4-Fluorophenylacetone 98%;4-Fluorophenylacetone,99%;1-(4-Fluorophenyl)acetone;4-Fluorophenylacetone pmk
CBNumber:
CB0459004
Molecular Formula:
C9H9FO
Molecular Weight:
152.17
MDL Number:
MFCD00000362
MOL File:
459-03-0.mol
MSDS File:
SDS
Last updated:2024-04-16 18:29:06

(4-Fluorophenyl)acetone Properties

Boiling point 106-107 °C/18 mmHg (lit.)
Density 1.139 g/mL at 25 °C (lit.)
refractive index n20/D 1.496(lit.)
Flash point 197 °F
storage temp. Sealed in dry,Room Temperature
solubility Methyl Acetate: 50 mg/ml
form clear liquid
color Light yellow to Yellow to Orange
Specific Gravity 1.139
Water Solubility insoluble
BRN 1936697
InChI InChI=1S/C9H9FO/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5H,6H2,1H3
InChIKey ZUEKIIWSVFBTCM-UHFFFAOYSA-N
SMILES C(C1=CC=C(F)C=C1)C(=O)C
CAS DataBase Reference 459-03-0(CAS DataBase Reference)
NIST Chemistry Reference (4-Fluorophenyl)acetone(459-03-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227
Precautionary statements  P210-P280-P403+P235-P501-P210e-P280a-P370+P378a-P501a
Hazard Codes  F,Xi
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  3
Hazard Note  Flammable
HazardClass  IRRITANT, FLAMMABLE
HS Code  29147090
NFPA 704
2
0 0

(4-Fluorophenyl)acetone price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 209457 (4-Fluorophenyl)acetone 98% 459-03-0 10g $313 2024-03-01 Buy
TCI Chemical F0535 4-Fluorophenylacetone >98.0%(GC) 459-03-0 5g $22 2024-03-01 Buy
TCI Chemical F0535 4-Fluorophenylacetone >98.0%(GC) 459-03-0 25g $86 2024-03-01 Buy
Alfa Aesar L11720 4-Fluorophenylacetone, 99% 459-03-0 1g $28.65 2024-03-01 Buy
Alfa Aesar L11720 4-Fluorophenylacetone, 99% 459-03-0 5g $91.65 2024-03-01 Buy
Product number Packaging Price Buy
209457 10g $313 Buy
F0535 5g $22 Buy
F0535 25g $86 Buy
L11720 1g $28.65 Buy
L11720 5g $91.65 Buy

(4-Fluorophenyl)acetone Chemical Properties,Uses,Production

Description

This intermediate, also known as (4-Fluorophenyl)acetone, presents as a dark yellow liquid. It is known to be insoluble in water. For best results, store in a tightly closed container in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 4-Fluorophenylacetone is incompatible with strong oxidizing agents. This chemical is a combustible liquid.

Chemical Properties

clear yellow liquid

Uses

4-Fluorophenylacetone is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It is a haloarylacetone derivative used in a study of reversed enantiopreference of an ω-transaminase by a single-point mutation.

Application

(4-Fluorophenyl)acetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors. It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor. (4-Fluorophenyl)acetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis. Brevibacterium sp. strain P7 was used as a model system and it has found that it inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.

917-54-4
405-50-5
459-03-0
Synthesis of (4-Fluorophenyl)acetone from Methyllithium and 4-Fluorophenylacetic acid

(4-Fluorophenyl)acetone Preparation Products And Raw materials

Global( 270)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Aoliqisi New Material Technology Co., Ltd.
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Zhejiang J&C Biological Technology Co.,Limited
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Xiamen Wonderful Bio Technology Co., Ltd.
+8613043004613 Sara@xmwonderfulbio.com China 305 58
Hunan aslsen technology co.,ltd
+8619313031929 aslsd@aslsen.com China 128 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Dorne Chemical Technology co. LTD
+86-13583358881 +86-18560316533 Ethan@dornechem.com China 294 58
Hubei Aumei New Material Co., Ltd.
+86-027-87366298 +8615927270571 tianyi@skbiology.cn China 294 58
Firsky International Trade (Wuhan) Co., Ltd
+8615387054039 admin@firsky-cn.com China 436 58
Nanjing Deda New Material Technology Ltd.
+8613223281135 niki@njdeda.com China 76 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58

View Lastest Price from (4-Fluorophenyl)acetone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluorophenylacetone pictures 2024-04-26 4-Fluorophenylacetone
459-03-0
US $10.00 / ASSAYS 1ASSAYS 99% 10 ton Dorne Chemical Technology co. LTD
4-Fluorophenylacetone pictures 2024-04-22 4-Fluorophenylacetone
459-03-0
US $10.00 / KG 1KG 99% 10 TONS Hunan aslsen technology co.,ltd
4-Fluorophenylacetone pictures 2024-04-22 4-Fluorophenylacetone
459-03-0
US $10.00 / kg 1kg 99% 1000 tons Hunan aslsen technology co.,ltd
(P-FLUOROPHENYL)ACETONE P-FLUORO BENZYL METHYL KETONE 4'-FLUOROPHENYLACETONE 4-FLUOROPHENYLACETONE 1-(4-FLUOROPHENYL)-2-PROPANONE 1-ACETONYL-4-FLUOROBENZENE 1-(4-Fluorophenyl)acetone 2-Propanone, 1-(4-fluorophenyl)- P-FLUORO ENZYL METHYL KETONE 4-Fluorophenylacetone,99% 4-Fluorophenylacetone 98% 4-Fluorophenylacetone98% Right fluorophenyl acetone 1-(2-Oxopropyl)-4-fluorobenzene 1-(p-Fluorophenyl)-2-propanone 3-(4-Fluorophenyl)-2-propanone 4-Fluorobenzyl Methyl Ketone 4-FLUOROPHENYLACETONE FOR SYNTHESIS 1-(4-Fluorophenyl)propan-2-one, 1-(4-Fluorophenyl)-2-oxopropane 4 - fluorine phenyl acetone 4-Fluorophenylacetone (4-Fluorophenyl)acetone 2-Propanone, 1-(4 cas 459-03-0 (4-Fluorophenyl)acetone> 4-Fluorophenylacetone 459-03-0 4-Fluorophenylacetone pmk 459-03-0 459-03-3 459-30-0 C9F1H9O1 FC6H4CH2COCH3 Building Blocks C9 Carbonyl Compounds Alphabetic Analytical Chromatography Product Catalog Analytical Standards FA - FL Organic Building Blocks Ketones Aromatic Ketones (substituted) Aromatics Intermediates & Fine Chemicals Pharmaceuticals Ketone C9 C9Alphabetic Carbonyl Compounds F FA - FL Ketones 459-03-0