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Astaxanthin

Product features Natural astaxanthin Production process Uses Health Benefits of Astaxanthin Side Effects of Astaxanthin Dosage

CAS No. 472-61-7
Chemical Name: Astaxanthin
Synonyms: AXN;Ovoeste;OVEOSTER;Ovoester;ASTAXANTHIN;astaxanthine;shrimp colour;ALLOXANTHIN(SH);ASTAXANTHIN(RG);Astaxanthin oil
CBNumber: CB0459594
Molecular Formula: C40H52O4
Formula Weight: 596.84
MOL File: 472-61-7.mol
Astaxanthin Property
Melting point : 215-216 °C
storage temp. : −20°C
solubility : DMSO: soluble1mg/mL (warmed)
Safety
Hazard Codes : Xn
Risk Statements : 20/21/22-36/37/38
Safety Statements : 24/25-36-26
WGK Germany : 3
HS Code : 29339990
Hazardous Substances Data: 472-61-7(Hazardous Substances Data)

Astaxanthin Chemical Properties,Usage,Production

Product features
Shrimp flavin is found in river crayfish shell, oysters and salmon, which is a sort of red carotenoid, It can be combined with the protein in vivo and show green, blue. There are antioxidant, anti-aging, anti-tumor, prevention of cardiovascular and cerebrovascular disease.
Astaxanthin is a kind of lutein, the most widely distributed in the animal kingdom. It is pink, and has unique coloring function, also can promote antibody production, enhancing animal immunity. On the aspects of the antioxidant and scavenging free radicals, the ability is stronger than β-carotene( (10 times). It is soluble in water and lipophilic, soluble in carbon disulfide, acetone, benzene and chloroform and other organic solvents. Astaxanthin is a kind of very potential carotenoid additives, and has a broad prospect in food, feed, cosmetics, pharmaceuticals and other fields. Foods which are rich in the astaxanthin include marine plants, Pluvialis microalgae, Phaffia rhodozyma, wild salmon, shrimp, salmon, rainbow trout and other seafood. Astaxanthin can bring many benefits to health, but not everyone can get enough, this is where the problem.
Natural astaxanthin
Natural astaxanthin also known as astacin, is a kind of precious health ingredients, is used for development to enhance immunity, anti-oxidation, anti-inflammatory, eyes and brain health, regulating blood lipids and other natural and healthy products. At present, the main used as a raw material for human health food and medicine; aquaculture (currently the main salmon, trout and salmon), poultry feed additive and additives of cosmetics.
It can significantly improve the body's immunity, because of its non-specific combination with skeletal muscle, can effectively remove the free radicals which are generated by the movement of the muscle cells, strengthen aerobic metabolism, so it has a significant anti fatigue effect.
It is only the carotenoids through blood brain barrier, with true anti-aging effect and effective antioxidant is the basis of all beauty activities. Owing to its powerful antioxidant, It can effectively wrinkle anti-aging, sunscreen whitening and except for chloasma caused by age. In the prevention and treatment for age related macular degeneration and improvement of retinal function, it has good effects. All of the above can clearly be confirmed in the United States.
The stability and antioxidant activity of synthetic astaxanthin also are lower than natural astaxanthin. Because of the hydroxyl (-OH) at ends of the molecule, astaxanthin can be esterification, resulting in not the same of its stability. More than 90% of natural astaxanthin is exist in ester form, and therefore more stable. Synthesic astaxanthin is the free state, therefore, the stability is not the same, must be embedded in order to stabilize. Because Left lateral structure of synthesic astaxanthin was only about 1/4, so it is only natural antioxidant of 1/4.
Production process
A method of production of chitin, astaxanthin, protein, calcium powder and biological fertilizer from shrimp shell, its production process is as follows:
1. The shrimp shell is cleaned and mechanical crushing to 5-10 mesh t.
2. The weight ratio of the shrimp shell powder and the shrimp shell was 1: 1-2, and the protease was added to the solution. According to different varieties of shrimp shell, the temperature of the enzyme solution was 30-70℃, pH value was 4-8, the time was 2-6 hours, and protease was 0.4%-1% of the shrimp shell in weight .
3. After the end of the enzyme solution, the temperature is up to 70-100℃ and then Enzyme bacteria is cool.
4. After that, adding organic solvent extraction, the weight ratio of organic solvent and shrimp shell was 1: 1-2, stirred closed fully 6-12 hours then cooling.
5. After full reaction, separate the liquid of shrimp and shrimp.
6. Shrimp liquid is divided into liquid and organic liquid.
Uses
Natural astaxanthin also known as astacin, is a kind of precious health ingredients, is used for development to enhance immunity, anti-oxidation, anti-inflammatory, eyes and brain health, regulating blood lipids and other natural and healthy products. At present, the main used as a raw material for human health food and medicine; aquaculture (currently the main salmon, trout and salmon), poultry feed additive and additives of cosmetics. It can significantly improve the body's immunity, because of its non-specific combination with skeletal muscle, can effectively remove the free radicals which are generated by the movement of the muscle cells, strengthen aerobic metabolism, so it has a significant anti fatigue effect.
Health Benefits of Astaxanthin
(1) Astaxanthin is a powerful antioxidant. The free radical scavenging activity of astaxanthin protects lipids from peroxidation and reduces oxidative damage of LDL-cholesterol (thereby reducing arterial plaque formation), cells, cell membranes, mitochondrial membranes. Astaxanthin increases strength and endurance.
(2) Astaxanthin seems to improve the immune system by increasing the number of antibody producing cells. Astaxanthin enhances antibody production by exerting actions on T-cells and T-helper cells. Astaxanthin is used to treat neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease.
(3) Astaxanthin protects the eyes and skin from sun radiation damage by quenching singlet and triplet oxygen. Studies with rats show that astaxanthin reduces retinal injury.
(4) Studies have shown the anti-cancer effects of astaxanthin in rodents. The inhibitory effect of astaxanthin on cancer is stronger han that of beta-carotene.
Side Effects of Astaxanthin
You should also know about the side effects of astaxanthin. No toxic side-effects are related with overdose of astaxanthin. However, mild to moderate side effects are noticed with high doses of it. Some side effects include:
  • Aplastic anemia
  • Eye damage because of crystal formation
  • Decreased libido
  • Reduction in blood pressure,
  • Enhanced skin pigmentation
  • Gynecomastia (abnormal enlargement of breasts in men)
  • Inhibited 5-alpha-reductase
  • Increased hair growth
  • Lowered eosinophil counts
  • Parathyroid intervention
  • Lowered serum calcium
  • Inhibited conversion of testosterone to dihydrotestosterone
Dosage
Research has shown that the optimal dosage of astaxanthin is 4 mg per day-which relates to 200 mg of a 2% extract.
It is of prime importance that when evaluating any Astaxanthin supplement that you ensure that you ingest 4 mg PER DAY-which would require 200 mg of a 2% extract-as used in our Anti-Aging Supplement.
Toxicity and symptoms of high intake Astaxanthin
Astaxanthin is practically non-toxic in acute animal studies at doses up to 18 grams. When tested for genotoxicity, there was no evidence for mutagenicity in Ames/Salmonella assays nor did it induce micronuclei when tested in vivo up to 2000 mg/kg in mice. There was no maternal, embryo-toxic or teratogenic effects in a teratology study in rabbits given up to 400 mg/kg over most of the gestational period.
No adverse effects were noted in a one-generation reproduction study at doses up to 400 mg/kg in rats. In multiple subchronic feeding studies in rats, astaxanthin did not produce any adverse toxicological effects.
Chemical Properties
Drak-Purple Solid
Uses
Carotenoid pigment found mostly in animal organisms, but also occuring in plants; thought to be the precursor of astacin. Animal studies indicate that it reduces blood glucose and ameliorates several parameters of the diabetic metabolic syndrome. It improves blood flow and vascular tone in models of hypertension.
Astaxanthin Preparation Products And Raw materials
Raw materials
Preparation Products
Astaxanthin Suppliers      Global( 154)Suppliers     
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd. 0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3230 55
Shaanxi Pioneer Biotech Co., Ltd. 18291449694; 029-84385017-8009
029-84385017 sales@pioneerbiotech.com China 2225 56
Nanjing Duolong Bio-tech Co.,Ltd. 18905173768
13222071610 52513593@qq.com China 3604 50
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 QQ:2851167782
028-81705658 2851167782@qq.com China 2717 56
Shanghai DND Pharm-Technology Co., Inc. +86 (21) 58783620
+86 (21) 58783595 sales@dndpharm.com China 108 57
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96832 76
INTATRADE GmbH +49 3493/605464
+49 3493/605470 sales@intatrade.de Germany 3589 66
future industrial shanghai co., ltd 021-61552785,400-0066-400
021-55660885 sales@jonln.com China 2091 65
Chemfun Medical Technology(Shanghai) Co., Ltd. 021-67220633 & 021-37212706
+86-21-67220638 chemfun@chemfun.net China 21909 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202,021-54302127,021-54308259,13764082696
+86-21-54291107 jerry.ma@hanhonggroup.com China 28718 64
 
472-61-7(Astaxanthin)Related Search:
Procyanidin Xanthophyll (3R,3)-all-trans-Astaxanthin ASTAXANTHIN-RICHEXTRACT ASTAXANTHIN MONOESTER ASTAXANTHIN-RICHPHAFFIARHODOZYMA 4'-Hydroxyacetophenone NATURAL ASTAXANTHIN 2'-Hydroxyacetophenone Lycopene 3,5,7-Nonatrien-2-one Canthaxanthin BETA-CAROTENE DECA-2,4,6,8-TETRAENAL 2,4,4-TRIMETHYL-2-CYCLOHEXEN-1-ONE ECHINENONE Zeaxanthin Astaxanthin
OVEOSTER (3S,3’S)-3,3’-Dihydroxy-.beta.,.beta.-carotene-4,4’-dione 472-61-7 3,3'-DIHYDROXY-B,B-CAROTENE-4,4'-DIONE 3,3-DIHYDROXY-B,B-CAROTENE-4,4-DIONE 3,3'-DIHYDROXY-BETA,BETA-CAROTENE-4,4'-DIONE ASTAXANTHIN AXN Astaxanthinenatural 3,3'-Dihydroxy-β,β-carotene-4,4'-dione C40H52O4 3,3Dhydroxy-4,4diketo-b-carotene Ovoeste 6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-(4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexenyl)-3,7,12,16-tetramethyl-octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethyl-cyclohex-2-en-1-one ALLOXANTHIN(SH) ASTAXANTHIN(RG) astaxanthine Carotenoids shrimp colour 3,3’-Dhydroxy-4,4’-diketo--carotene Ovoester Intermediates & Fine Chemicals Pharmaceuticals (3S,3'S)-3,3'-Dihydroxy-β,β-carotene-4,4'-dione (3S,3'S)-Astaxanthin (3S,3'S)-trans-Astaxantin all-E-Astaxanthin all-trans-Astaxanthin Astaxanthin,98+% Astaxanthin (3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione) ASTAXANTHIN (SH) Astaxanthin Discontinued Astaxanthin (crystalline) Astaxanthin Powder Plant extracts HaeMatococcus Powder trans-Astaxanthin Astaxanthin oil
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