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SNX-0723

SNX-0723 structure

CAS No.: 1073969-18-2

Chemical Name:: SNX-0723

Synonyms: SNX-0723;Benzamide, 2-fluoro-6-[[(3S)-tetrahydro-3-furanyl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indol-1-yl)-

CBNumber:: CB04668523

Molecular Formula:: C22H26FN3O3

Molecular Weight:: 399.46

MDL Number:

MOL File:: 1073969-18-2.mol

Last updated:2023-05-21 10:59:17

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SNX-0723 Properties

Boiling point	568.5±50.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 20.83 mg/mL (52.15 mM; ultrasonic and warming and heat to 60°C)
pka	14.51±0.50(Predicted)

SNX-0723 Chemical Properties,Uses,Production

Biological Activity

SNX-0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX-0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX-0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM[1].

References

[1]. Dora Posfai, et al. Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01799-17.

SNX-0723 Preparation Products And Raw materials

Raw materials

Preparation Products

SNX-0723 Suppliers

Global( 6)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Block Chemical Technology (Shanghai) Co., Ltd.	021-20432219 13918097649	li_jinfei@acblock-lab.com	China	9913	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	vip@med-life.cn	China	5019	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Block Chemical Technology (Shanghai) Co., Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

SNX-0723 Benzamide, 2-fluoro-6-[[(3S)-tetrahydro-3-furanyl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indol-1-yl)- 1073969-18-2