Anti-JAM-A antibody, Mouse monoclonal
- CAS No.
- Chemical Name:
- Anti-JAM-A antibody, Mouse monoclonal
- Synonyms
- Anti-JAM-A antibody, Mouse monoclonal
- CBNumber:
- CB04669368
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-JAM-A antibody, Mouse monoclonal price More Price(1)
Anti-JAM-A antibody, Mouse monoclonal Chemical Properties,Uses,Production
Uses
Anti-JAM-A antibody, Mouse monoclonal has been used in:
- western blotting
- staining for confocal microscopy
- immunoprecipitation
- immunocytochemistry
- flow cytometry
General Description
Anti-JAM-A antibody, Mouse monoclonal, (mouse IgG1 isotype) is derived from the hybridoma J10.4 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant human JAM. Junctional adhesion molecule A (JAM-A) is expressed at tight junctions of endothelial and epithelial cells as well as on a variety of hematopoietic cells. It belongs to the transmembrane IgG glycoprotein family and is also expressed in monocytes, lymphocytes, neutrophils, dendritic cells, platelets, and spermatozoa. The JAM-A or F11R gene is mapped to human chromosome 1q23.3.
Biochem/physiol Actions
Junctional adhesion molecule A(JAM-A) function has been linked with regulation of cell migration/invasion, platelet adhesion, cell polarity, cell proliferation, and epithelial or endothelial barrier function. However, the mechanisms by which JAM-A mediates these processes have not been well elucidated. JAM-A functional significance is connected with inflammation, angiogenesis, hypertension, ischemia/reperfusion, and atherosclerosis. JAM-A has also been linked to breast, endometrial, renal cell carcinomas and gastric cancer.
Anti-JAM-A antibody, Mouse monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-JAM-A antibody, Mouse monoclonal Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |