Clopamide
- CAS No.
- 636-54-4
- Chemical Name:
- Clopamide
- Synonyms
- Aquex;DT-327;Adurix;CLOPAMIDE;Brinaldix;CLOPAMIDUM;Clopamide CRS;ChlosudiMepriMyl;Clopamide (10mM in DMSO);N-(cis-2',6'-DiMethyl-1'-pip
- CBNumber:
- CB0469173
- Molecular Formula:
- C14H20ClN3O3S
- Molecular Weight:
- 345.84
- MDL Number:
- MFCD00941495
- MOL File:
- 636-54-4.mol
- MSDS File:
- SDS
| Melting point | 248-249℃ |
|---|---|
| Density | 1.39±0.1 g/cm3(Predicted) |
| RTECS | CV2338875 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly) |
| pka | 9.41±0.60(Predicted) |
| color | Pale Yellow to Light Yellow |
| CAS DataBase Reference | 636-54-4(CAS DataBase Reference) |
| FDA UNII | 17S83WON0I |
| ATC code | C03BA03 |
| EPA Substance Registry System | Benzamide, 3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-, rel- (636-54-4) |
Clopamide price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000848 | Clopamide for system suitability European Pharmacopoeia (EP) Reference Standard | 636-54-4 | y0000848 | $161 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0000833 | Clopamide European Pharmacopoeia (EP) Reference Standard | 636-54-4 | y0000833 | $153 | 2024-03-01 | Buy |
| Alfa Aesar | J67183 | Clopamide, 98% | 636-54-4 | 500mg | $55.1 | 2021-12-16 | Buy |
| Cayman Chemical | 19356 | Clopamide ≥98% | 636-54-4 | 500mg | $46 | 2024-03-01 | Buy |
| TRC | C587160 | Clopamide | 636-54-4 | 10mg | $180 | 2021-12-16 | Buy |
Clopamide Chemical Properties,Uses,Production
Chemical Properties
White or almost white, hygroscopic, crystalline powder
Originator
Brinaldix,Novartis
Uses
Antihypertensor;Gonad stimuling agent
Uses
Clopamide is a thiazide-like diuretic that inhibits sodium/chloride cotransporters in the proximal convoluted tubule of the kidney, which prevents the reabsorption of sodium and chloride. This compound is intended for research purposes only.
Uses
Antihypertensive; diuretic.
Definition
ChEBI: 4-chloro-N-[(2S,6R)-2,6-dimethyl-1-piperidinyl]-3-sulfamoylbenzamide is a sulfonamide.
Manufacturing Process
To a solution of 5.5 g of 3-chlorsulfonyl-4-chlorobenzoylchloride in 20 ml chlorobenzole 3.3 g of 1-amino-cis-2,6-dimethylpiperidin-hydrochloride slowly was added at room temperature. Reaction mixture was heated to 100°-105°C during 8 h, then it was cooled to room temperature. The precipitated crystals of N-[cis-2,6-dimethyl-piperidyl-(1)]-3-chlorsulfonyl-4-chlorobenzoylamide were filtered and dried at 100°C under vacuo, then was treated by ammonium at room temperature. The obtained product was chromatographed (aluminum oxide; eluent: chloroform-methanol 9:1 and methanol-ether) to give N-[cis- 2,6-dimethylpiperidyl-(1)]-3-sulfamyl-4-chlorbenzoylamide, melting point 235°-237°C.
brand name
Aquex (Novartis).
Therapeutic Function
Diuretic, Antihypertensive
Clopamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 992 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18456 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from Clopamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | Clopamide
636-54-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
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- Clopamide
636-54-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd