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(2R,3R)-2-Amino-3-methylpentanoic acid

CAS No.
319-78-8
Chemical Name:
(2R,3R)-2-Amino-3-methylpentanoic acid
Synonyms
D-ISOLEUCINE;D-Ile;H-D-ILE-OH;D-Ile-OH;d-isoleucin;(r)-isoleucine;D-IsoL;D-lle-OH;H-D-lle-OH;D-lsoleucine
CBNumber:
CB0473220
Molecular Formula:
C6H13NO2
Molecular Weight:
131.17
MDL Number:
MFCD00064221
MOL File:
319-78-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-07 08:03:05

(2R,3R)-2-Amino-3-methylpentanoic acid Properties

Melting point 272-274 °C
alpha -37 º (c=5, 1 N HCl 24 ºC)
Boiling point 225.8±23.0 °C(Predicted)
Density 1.1720 (estimate)
refractive index -40.5 ° (C=4, 6mol/L HCl)
storage temp. Sealed in dry,Room Temperature
solubility Aqueous Acid (Slightly), Water (Slightly)
pka 2.57±0.24(Predicted)
form Solid
color White to Off-White
Major Application cell analysis
InChI InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m1/s1
InChIKey AGPKZVBTJJNPAG-RFZPGFLSSA-N
SMILES C(O)(=O)[C@@H]([C@H](C)CC)N
CAS DataBase Reference 319-78-8(CAS DataBase Reference)
FDA UNII V87GJA0G54
EPA Substance Registry System D-Isoleucine (319-78-8)
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  40
Safety Statements  24/25-36-22
WGK Germany  3
RTECS  NR4700000
HS Code  29224995
Storage Class 11 - Combustible Solids
Toxicity rat,LD50,intraperitoneal,6822mg/kg (6822mg/kg),BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)LUNGS, THORAX, OR RESPIRATION: DYSPNEA,Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956.
NFPA 704
1
1 0

(2R,3R)-2-Amino-3-methylpentanoic acid price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I7634 D-Isoleucine ≥98% (TLC) 319-78-8 250mg $509 2026-04-30 Buy
Sigma-Aldrich I7634 D-Isoleucine ≥98% (TLC) 319-78-8 1g $1650 2026-04-30 Buy
TCI Chemical I0179 H-D-Ile-OH 319-78-8 250MG $92 2025-07-31 Buy
TCI Chemical I0179 H-D-Ile-OH 319-78-8 1G $231 2025-07-31 Buy
Usbiological I8940-10 D-Isoleucine 319-78-8 1g $369 2026-06-03 Buy
Product number Packaging Price Buy
I7634 250mg $509 Buy
I7634 1g $1650 Buy
I0179 250MG $92 Buy
I0179 1G $231 Buy
I8940-10 1g $369 Buy

(2R,3R)-2-Amino-3-methylpentanoic acid Chemical Properties, Uses, Production

Chemical Properties

white to very slightly yellow powder

Uses

D-Isoleucine is not biosynthesized in the human body and is therefore categorized as an essential amino acid that must be obtained through diet. It is also an important building block that is used in the formation of hemoglobin in humans.

Uses

May contain up to 10% allo-isomer.

Definition

ChEBI: The D-enantiomer of isoleucine.

Biological Activity

D-Isoleucine may be used to help characterize and differentiate various D-amino acid oxidases. D-Isoleucine may be used to differentiate the activities of D- and L-isoleucine in processes such as the induction of pigmentation in B16F0 melanoma cells.

(2R,3R)-2-Amino-3-methylpentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 349)
Supplier Tel Email Country ProdList Advantage
Nanjing Derno Pharmaceutical Technology Co., Ltd. 02585057128;025-86957866 13952093866 sales@dernopharm.com China 949 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Sichuan Tongsheng Amino acids Co.,Ltd. 0838-2274206 17340404235 sales@biots.cn China 300 66
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44852 61
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64

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View Latest Price from (2R,3R)-2-Amino-3-methylpentanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-lsoleucine pictures 2026-10-09 D-lsoleucine
319-78-8
1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
D-lsoleucine pictures 2026-09-30 D-lsoleucine
319-78-8
1kg 98% 99% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
D-Isoleucine pictures 2026-07-14 D-Isoleucine
319-78-8
$51.00-178.00 99.16% 10g TargetMol Chemicals Inc.
  • D-lsoleucine pictures
  • D-lsoleucine
    319-78-8
  • $0.00
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • D-lsoleucine pictures
  • D-lsoleucine
    319-78-8
  • 98% 99%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • D-Isoleucine pictures
  • D-Isoleucine
    319-78-8
  • $51.00-178.00
  • 99.16%
  • TargetMol Chemicals Inc.
(2R,3R)-2-Amino-3-methylvaleric acid D-Isoleucine≥ 98% (TLC) D(-)-ISOLEUCINE [-]-2-AMINO-3-METHYLPENTANOIC ACID H-D-lle-OH D-isoleucine (99% ee/glc) D-ISOLEUCINE, (2R,3R)-2-AMINO-3-METHYL-PENTANOIC ACID (2R,3R)-2-AMINO-3-METHYLPENTANOIC ACID D-Isoleucine,98% D-lsoleucine D-IsoL (2R,3R)-2-Amino-3-methylpentanoic acid USP/EP/BP dextro-isoleucine TIANFUCHEM--High purity 319-78-8 (2R,3R)-2-Amino-3-methylpentanoic acid D-Isoleucine extrapure, 98% 8-Dihydroxycoumarin (r)-isoleucine d-isoleucin Bedaquiline Monomer D-Isoleucine-OH D-Isoleucine, 10 mM in DMSO D-Isoleucine D-lle-OH D-Ile D-Ile-OH D-ISOLEUCINE H-D-ILE-OH 319-78-8 Amino Acids and Peptides BioChemical Modified Amino Acids I - Z Biochemicals and Reagents Amino Acid Derivatives Amino Acids and Derivatives alpha-Amino Acids Amino Acids Biochemistry Amino Acids bc0001