Calcium gluconate
- CAS No.
- 299-28-5
- Chemical Name:
- Calcium gluconate
- Synonyms
- glucal;CALCIUM D-GLUCONATE;Biocal;Calciofon;GLUCONIC ACID CALCIUM SALT;ebucin;kalpren;novocal;calcipur;calcicol
- CBNumber:
- CB0473578
- Molecular Formula:
- C12H22CaO14
- Molecular Weight:
- 430.37
- MDL Number:
- MFCD00064209
- MOL File:
- 299-28-5.mol
- MSDS File:
- SDS
| Melting point | 195°C |
|---|---|
| alpha | 10.2 º (c=1, H2O 22 ºC) |
| Boiling point | 400℃[at 101 325 Pa] |
| Density | 1.677[at 20℃] |
| vapor pressure | 0.004Pa at 20℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Sparingly soluble in water, freely soluble in boiling water. |
| form | Crystals or Crystalline Powder |
| color | White |
| PH | pH;6.0～8.0 |
| Odor | at 100.00?%. odorless |
| Water Solubility | 3.3 g/100mL |
| Hydrolytic Sensitivity | 0: forms stable aqueous solutions |
| Merck | 14,1669 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | KYUVBRZSDFBLTH-OSQBQZLYSA-M |
| LogP | -5.31 at 20℃ |
| CAS DataBase Reference | 299-28-5(CAS DataBase Reference) |
| FDA 21 CFR | 184.1199; 582.1199; 582.6199; 310.545 |
| Substances Added to Food (formerly EAFUS) | CALCIUM GLUCONATE |
| SCOGS (Select Committee on GRAS Substances) | Calcium gluconate |
| EWG's Food Scores | 1 |
| FDA UNII | SQE6VB453K |
| NCI Dictionary of Cancer Terms | calcium gluconate |
| NCI Drug Dictionary | calcium gluconate |
| ATC code | A12AA03,D11AX03 |
| EPA Substance Registry System | D-Gluconic acid, calcium salt (2:1) (299-28-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | EW2100000 | |||||||||
| TSCA | No | |||||||||
| HS Code | 29181600 | |||||||||
| Toxicity | dog,LDLo,intravenous,1987mg/kg (1987mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 47, Pg. 183, 1933. | |||||||||
| NFPA 704 |
|
Calcium gluconate price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2669 | Calcium Gluconate Anhydrous Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500?mg | 299-28-5 | 500MG | $200 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1086822 | Calcium gluconate anhydrous United States Pharmacopeia (USP) Reference Standard | 299-28-5 | 200mg | $174.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | C8231 | Calcium D-gluconate anhydrous, meets USP testing specifications (Not intended for use in preparing injectable dosage forms.) | 299-28-5 | 1kg | $311 | 2023-06-20 | Buy |
| TCI Chemical | G0037 | Calcium Gluconate Monohydrate >98.0%(T) | 299-28-5 | 25g | $22 | 2022-04-27 | Buy |
| TCI Chemical | G0037 | Calcium Gluconate Monohydrate >98.0%(T) | 299-28-5 | 500g | $49 | 2022-04-27 | Buy |
Calcium gluconate Chemical Properties,Uses,Production
Description
Calcium gluconate is the calcium salt of gluconate, being an oxidative product of glucose containing 9.3% calcium. Calcium gluconate is a kind of mineral supplement and medication. It can be used for vein injection to treat the low blood calcium, high blood potassium, and magnesium toxicity. It is required only when there is not enough calcium in the diet. It is also used for the treatment of black widow spider bites to relieve muscle cramping and treatment of osteoporosis or rickets. It can also be used to decrease the capillary permeability in allergic conditions, nonthrombocytopenic purpura and exudative dermatoses.
References
http://www.drugbank.ca/drugs/DB11126 https://en.wikipedia.org/wiki/Calcium_gluconate
Chemical Properties
white crystalline powder or granules
Uses
Calcium Gluconate is used as an inert ingredient in pesticide formulations applied to crops. It is also used as a supplement to fortify beverages and foods lacking a sufficient amount of calcium.
Uses
In sewage purification; in coffee powders to prevent caking.
Uses
analgesic, antipyretic
Uses
Calcium Gluconate is a white crystalline granule or powder that functions as a firming agent, formulation aid, sequestrant, and sta- bilizer. at room temperature the anhydrous form has a solubility of approximately 1 g in 30 ml of water, which improves in boiling water to approximately 1 g in 5 ml of water. it also exists as calcium gluconate (monohydrate). it is used as a source of calcium ions for sodium alginate gels, and as a calcium fortifier in baked goods, pud- dings, and dairy product analogs. it functions as a coagulation aid in milk and instant pudding powders and as a means of masking the bitter aftertaste of some artificial sweeteners.
Definition
ChEBI: Calcium gluconate is the calcium salt of D-gluconic acid. It has a role as a nutraceutical. It contains a D-gluconate.
brand name
Calglucon (Novartis).
Flammability and Explosibility
Non flammable
Industrial uses
calcium gluconate [Ca(C6H11O7)2] is used as a food additive in vitamin pills.injection of a 10% calcium gluconate has been recommended. It has to be kept in mind that the plasma Ca2+ level and any changes to the electrocardiogram (ECG) have to be carefully monitored.
Clinical Use
Hypocalcaemia
Safety Profile
Moderately toxic by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects in infants by intramuscular route: dermatitis and fever. When heated to decomposition it emits acrid smoke and fumes. See also CALCIUM COMPOUNDS.
Veterinary Drugs and Treatments
Calcium salts are used for the prevention or treatment of hypocalcemic conditions.
Drug interactions
Potentially hazardous interactions with other drugs
Can impair absorption of some drugs, e.g. iron,
ciprofloxacin.
Metabolism
Calcium is absorbed mainly from the small intestine by active transport and passive diffusion. About one-third of ingested calcium is absorbed although this can vary depending upon dietary factors and the state of the small intestine. 1,25-Dihydroxycholecalciferol (calcitriol), a metabolite of vitamin D, enhances the active phase of absorption. Excess calcium is mainly excreted renally. Unabsorbed calcium is eliminated in the faeces, together with that secreted in the bile and pancreatic juice. Minor amounts are lost in the sweat, skin, hair, and nails.
Purification Methods
Dissolve it in H2O, filter and precipitate it by adding MeOH. Filter off the solid and dry it in a vacuum at 85o. Alternatively, dissolve it in H2O, filter (from insoluble inorganic Ca) and evaporate it to dryness under vacuum at 85o. [March et al. J Am Pharm Assoc 41 366 1952, Beilstein 3 IV 1255.]
Calcium gluconate Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zibo Wei Bin Import & Export Trade Co. Ltd. | +86-0533-2091136 +8613864437655 | ziboweibinmaoyi@163.com | China | 100 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 893 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
View Lastest Price from Calcium gluconate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-22 | Calcium Gluconate
299-28-5
|
US $0.00 / kg | 1kg | 98.5% | 20tons | Sinoway Industrial co., ltd. | |
 |
2024-04-07 | Calcium gluconate
299-28-5
|
US $100.00 / kg | 1kg | 99% | 10 | Zibo Wei Bin Import & Export Trade Co. Ltd. | |
 |
2024-03-26 | Calcium Gluconate
299-28-5
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd |
-
- Calcium Gluconate
299-28-5
- US $0.00 / kg
- 98.5%
- Sinoway Industrial co., ltd.
-
- Calcium gluconate
299-28-5
- US $100.00 / kg
- 99%
- Zibo Wei Bin Import & Export Trade Co. Ltd.
-
- Calcium Gluconate
299-28-5
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd