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CARBACYCLIN

CAS No.
69552-46-1
Chemical Name:
CARBACYCLIN
Synonyms
CPGI;Carba pgx;Carba-PGI2;CARBACYCLIN;Carbacycline;6A-Carba-pgi2;6,9-Methano-pgi2;6,9-Methano pgi2;CARBACYCLIC PGI2;CARBOCYCLIC PGI2
CBNumber:
CB0475042
Molecular Formula:
C21H34O4
Molecular Weight:
350.49
MDL Number:
MFCD00210824
MOL File:
69552-46-1.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:25

CARBACYCLIN Properties

Melting point 65-67℃
Boiling point 514.8±50.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble at 20mg/ml in ethanol.
form Solid
pka 4.77±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P280h-P301+P312a-P304+P340-P321-P501a
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  22-36
WGK Germany  3
NFPA 704
3
2 0

CARBACYCLIN price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J67199 Carbacyclin, 99% 69552-46-1 0.5mg $164.65 2024-03-01 Buy
Alfa Aesar J67199 Carbacyclin, 99% 69552-46-1 1mg $309.65 2024-03-01 Buy
Cayman Chemical 18210 Carbaprostacyclin ≥98% 69552-46-1 100μg $93 2024-03-01 Buy
Cayman Chemical 18210 Carbaprostacyclin ≥99% 69552-46-1 500μg $153 2024-03-01 Buy
Cayman Chemical 18210 Carbaprostacyclin ≥99% 69552-46-1 1mg $143 2021-12-16 Buy
Product number Packaging Price Buy
J67199 0.5mg $164.65 Buy
J67199 1mg $309.65 Buy
18210 100μg $93 Buy
18210 500μg $153 Buy
18210 1mg $143 Buy

CARBACYCLIN Chemical Properties,Uses,Production

Uses

Carbacyclin acts as a converter of human white to bright adipocytes. Also used in the treatment of high-risk acute lymphoblastic leukemia potentiating the activity of anti-cancer therapeutics.

Uses

Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.

Definition

ChEBI: Carbaprostacyclin is a prostanoid.

CARBACYCLIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 33)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3296 57
Chengdu Saiousi Pharmaceutical Co., Ltd 028-64971018 18108168130 China 1781 55
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5E,13E-DIEN-1-OIC ACID 6A-CARBA-PROSTAGLANDIN I2 carboprostacyclin 6,9-Methanoprostaglandin I2 6a-Carba-prostaglandinI2, CarbocyclicPGI2 (5E)-6a-Carbaprostaglandin 12 5-[(1β,3E,5β,6R)-6β-[(1E,3S)-3-Hydroxy-1-octenyl]-7α-hydroxybicyclo[3.3.0]octane-3-ylidene]pentanoic acid 5-[(2E,3aS,5R,6aβ)-Octahydro-5α-hydroxy-4β-[(1E,3S)-3-hydroxy-1-octenyl]pentalen-2-ylidene]pentanoic acid (5E)-6A-Carba-prostaglandin I2 6,9-Methano pgi2 6,9-Methano-pgi2 6A-Carba-pgi2 9alpha-Deoxy-9alpha-methylene-pgi2 Carba pgx Carbacycline Carbacyclin (Carbocyclic PGI2) CARBACYCLIC PGI2 CARBACYCLIN CARBAPROSTACYCLIN CARBOCYCLIC PGI2 CARBOCYCLIC PGL2 CPGI Pentanoic acid,5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-2(1H)-pentalenylidene]-,(5E)- Carba-PGI2 Carbacyclin (Carbocyclic PGI?) 69552-46-1 BioChemical Biochemicals and Reagents Prostaglandins Lipids Fatty Acids