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Tobramycin sulfate

Tobramycin sulfate
Tobramycin sulfate structure
CAS No.
49842-07-1
Chemical Name:
Tobramycin sulfate
Synonyms
obracine;tenemicin;Tobramycin sulfate;TOBRAMYCIN SULPHATE;TobraMycin Sulfate API;1-epitobramycinsulfate;TOBRAMYCIN SULFATE SALT;TobraMycin sulfate research grade;d-6-trideoxy-alpha-d-ribohexopyranosyl-(1-4))-2-deoxysulfate(salt);streptamine,o-3-amino-3-deoxy-alpha-d-glucopyranosyl-(1-6)-o-(2,6-diamino-2,3,
CBNumber:
CB0475411
Molecular Formula:
C18H39N5O13S
Formula Weight:
565.59
MOL File:
49842-07-1.mol

Tobramycin sulfate Properties

SAFETY
  • Risk and Safety Statements
Hazard Codes  T
Risk Statements  61-20/21/22
Safety Statements  53-22-36/37/39-45
WGK Germany  3

Tobramycin sulfate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J62995 Tobramycin sulfate 49842-07-1 100mg $43 2018-11-20 Buy
Alfa Aesar J62995 Tobramycin sulfate 49842-07-1 1g $283 2018-11-20 Buy

Tobramycin sulfate Chemical Properties,Uses,Production

Uses

Nebcin (Lilly).

Clinical Use

Introduced in 1976, tobramycin sulfate (Nebcin) is the mostactive of the chemically related aminoglycosides called nebramycinsobtained from a strain of Streptomyces tenebrarius Five members of the nebramycin complex have beenidentified chemically.
Factors 4 and 4' are 6"-O-carbamoylkanamycin B andkanamycin B, respectively; factors 5' and 6 are 6"-O-carbamoyltobramycinand tobramycin; and factor 2 isapramycin, a tetracyclic aminoglycoside with an unusual bicycliccentral ring structure. Kanamycin B and tobramycinprobably do not occur in fermentation broths per se but areformed by hydrolysis of the 6-O"-carbamoyl derivatives inthe isolation procedure.
The most important property of tobramycin is its activityagainst most strains of P. aeruginosa, exceeding that of gentamicinby twofold to fourfold. Some gentamicin-resistantstrains of this troublesome organism are sensitive to tobramycin,but others are resistant to both antibiotics. OtherGram-negative bacilli and staphylococci are generally moresensitive to gentamicin. Tobramycin more closely resembleskanamycin B in structure (it is 3'-deoxykanamycin B).

Tobramycin sulfate Preparation Products And Raw materials

Raw materials

Preparation Products


Tobramycin sulfate Suppliers

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