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DL-THIORPHAN

DL-THIORPHAN
DL-THIORPHAN structure
CAS No.
76721-89-6
Chemical Name:
DL-THIORPHAN
Synonyms
C01619;THIORPHAN;Thiorphan-d5;DL-THIORPHAN;THIORPHAN (DL);Bisoprolol FuMarate IMpurity-Q;(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY;DL-3-MERCAPTO-2-BENZYLPROPANOYL-GLYCINE;(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY-OH;((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLY-OH
CBNumber:
CB0479626
Molecular Formula:
C12H15NO3S
Formula Weight:
253.32
MOL File:
76721-89-6.mol

DL-THIORPHAN Properties

Melting point:
138-140 °C
RTECS 
MC0596440
storage temp. 
-15°C
solubility 
ethanol: 50 mg/mL, clear, colorless
form 
White solid
BRN 
4872101
CAS DataBase Reference
76721-89-6

SAFETY

Safety Statements  22-24/25
WGK Germany  3
10
HS Code  29309090

DL-THIORPHAN price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T6031 DL-Thiorphan ≥98% (TLC) 76721-89-6 5mg $169 2018-11-13 Buy
Sigma-Aldrich 598510 DL-Thiorphan 76721-89-6 10mg $294 2018-11-20 Buy
Alfa Aesar J62557 DL-Thiorphan 76721-89-6 25mg $416 2018-11-13 Buy
Cayman Chemical 15600 Thiorphan ≥95% 76721-89-6 5mg $49 2018-11-13 Buy
Cayman Chemical 15600 Thiorphan ≥95% 76721-89-6 10mg $93 2018-11-13 Buy

DL-THIORPHAN Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

An Enkephalinase inhibitor

Uses

The active metabolite

Uses

Thiorphan is a potent inhibitor of neprilysin, a membrane metallo-endopeptidase that cleaves peptide hormones, such as enkephalins, glucagon, and bradykinin (Ki = 4-140 nM). It is much less effective against neprilysin-2 (IC50 = 22.1 μM), angiotensin-converting enzyme, and endothelin-converting enzyme-1. Thiorphan can be produced in vivo via the metabolism of the prodrug acetorphan. Neprilysin is overexpressed in many forms of cancer and may play a role in protecting against Alzheimer’s disease.

DL-THIORPHAN Preparation Products And Raw materials

Raw materials

Preparation Products


DL-THIORPHAN Suppliers

Global( 38)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
0086-411-39042497
0086-411-39042693 sales@alphabiopharm.com China 1954 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8430 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
Alabiochem Tech.Co., Ltd. 0086-512-58900862; 400-0707-518; 0086-512-56727736
0086-512-56765862 sales@alabiochem.com China 944 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202,021-54308259
+86-21-54291107 info@hanhonggroup.com China 43389 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32492 50
Syntechem Co.,Ltd Please Email
E-Mail Inquiry info@syntechem.com China 13074 57
Shanghai LiuShi Pharmaceutical Technology Co., Ltd. 021-60135539
021-38721356 shlschemical@hotmail.com China 9947 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025- 66028182;18626450290
(1)02557626880 yftan@aikonchem.com China 21711 55

76721-89-6(DL-THIORPHAN)Related Search:


  • N-[(RS)-2-BENZYL-3-MERCAPTOPROPANOYL]-GLYCINE
  • (+/-)-N-(3-MERCAPTO-2-BENZYLPROPIONYL)GLYCINE
  • N-ALPHA-(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLYCINE
  • THIORPHAN
  • THIORPHAN (DL)
  • ((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLYCINE
  • ((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLY-OH
  • 2-Mercaptomethyl-3-phenyl-propionylamino-acetic Acid, D,L-3-Mercapto-2-benzylpropanoylglycine,
  • (±)-N-(3-Mercapto-2-benzylpropionyl)glycine, DL-3-Mercapto-2-benzylpropanoylglycine
  • rac-N-[(2R*)-3-Mercapto-2-benzylpropionyl]glycine
  • C01619
  • 2-MercaptoMethyl-3-phenylpropionylaMinoacetic Acid
  • DL-Thiorphan - CAS 76721-89-6 - Calbiochem
  • (DL-3-Mercapto-2-benzylpropionyl)-Gly-OH, (DL-3-Mercapto-2-benzylpropanoyl)-Gly-OH
  • Bisoprolol FuMarate IMpurity-Q
  • Thiorphan-d5
  • 2-(2-benzyl-3-MercaptopropanaMido)acetic acid
  • (DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY
  • DL-3-MERCAPTO-2-BENZYLPROPANOYL-GLYCINE
  • (DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLY-OH
  • DL-THIORPHAN
  • 76721-89-6
  • BioChemical
  • Biochemicals and Reagents
  • Organic Covalent Modifiers
  • Enzyme Inhibitors by Enzyme
  • N-[2-(MercaptoMethyl)-1-oxo-3-phenylpropyl]glycine
  • 2-[[2-(Benzyl)-3-sulfanylpropanoyl]aMino]acetic acid
  • Enzyme Inhibitors by Type
  • Enzymes, Inhibitors, and Substrates
  • D to K
  • Enzyme Inhibitors
  • Enkephalinase
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Inhibitors
  • Sulfur & Selenium Compounds
  • Aromatics
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