N-Acetyl-L-proline
- CAS No.
- 68-95-1
- Chemical Name:
- N-Acetyl-L-proline
- Synonyms
- AC-PRO-OH;AC-PROLINE;NSC 280718;N-AC-L-PRO;N-Ac-Pro-OH;Ac-L-Pro-Oh;N-Acetyl-Pro;AC-PYRD(2)-OH;Acetylproline;N-ACETYL-L-PRO
- CBNumber:
- CB0481658
- Molecular Formula:
- C7H11NO3
- Molecular Weight:
- 157.17
- MDL Number:
- MFCD00020837
- MOL File:
- 68-95-1.mol
- MSDS File:
- SDS
Melting point | 115-117 °C |
---|---|
alpha | -86 º (c=1 EtOH) |
Boiling point | 366.2±35.0 °C(Predicted) |
Density | 1.274±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly), Water (Slightly) |
form | Powder |
pka | 3.69±0.20(Predicted) |
color | White to off-white |
BRN | 83200 |
InChI | InChI=1S/C7H11NO3/c1-5(9)8-4-2-3-6(8)7(10)11/h6H,2-4H2,1H3,(H,10,11)/t6-/m0/s1 |
InChIKey | GNMSLDIYJOSUSW-LURJTMIESA-N |
SMILES | C(O)(=O)[C@@H]1CCCN1C(C)=O |
CAS DataBase Reference | 68-95-1(CAS DataBase Reference) |
FDA UNII | CC8XZ138VZ |
NIST Chemistry Reference | L-proline, 1-acetyl-(68-95-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
N-Acetyl-L-proline price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A0783 | N-Acetyl-L-proline | 68-95-1 | 1g | $64.4 | 2024-03-01 | Buy |
Sigma-Aldrich | A0783 | N-Acetyl-L-proline | 68-95-1 | 5g | $140 | 2023-06-20 | Buy |
Alfa Aesar | L14300 | N-Acetyl-L-proline, 99% | 68-95-1 | 1g | $36.3 | 2023-06-20 | Buy |
Alfa Aesar | L14300 | N-Acetyl-L-proline, 99% | 68-95-1 | 5g | $106 | 2023-06-20 | Buy |
Usbiological | 235177 | Acetyl-L-proline 99+% | 68-95-1 | 5g | $200 | 2021-12-16 | Buy |
N-Acetyl-L-proline Chemical Properties,Uses,Production
Chemical Properties
white to off-white powder
Uses
N-Acetyl-L-proline is an aminoacid used in the synthesis of pharmaceutical compounds useful in preventing and treating disorders and syndromes associated with the nervous, vascular, musculoskeletal, o r cutaneous systems.
Definition
ChEBI: N-acetyl-L-proline is a N-acetyl-L-amino acid, a N-acylpyrrolidine, a pyrrolidinemonocarboxylic acid and a L-proline derivative.
Biochem/physiol Actions
N-acetyl-L-proline is an analog of the COOH-terminal dipeptide portion of preferred substrates of angiotensin-converting enzyme (ACE). It may be used in studies of the binding of substrates and inhibitors by ACE and to differentiate the specificities of various aminoacylases.
References
[1] Jingxuan Qiu. “Solubility Behavior and Polymorphism of N-Acetyl-l-proline in 16 Individual Solvents from 283.15 to 323.15 K.” Journal of Chemical & Engineering Data 66 3 (2021): 1533–1542.
Description
N-Acetyl-L-proline (NALP) is an N-acetyl derivative of L-proline, which has wide application in medicine and is commonly utilized as a biologically active supplement. It can also act as an intermediate for synthesizing pharmaceuticals for preventing and treating some disorders and syndromes associated with the nervous, vascular, musculoskeletal, or cutaneous systems. In laboratories, it could play the role of a simple model for the secondary structure of proline-containing peptides. NALP can be acetylated from L-proline via a standard method, in the environment of acetic acid, or by the action of acetic anhydride on aqueous solutions of the products of the alkaline hydrolysis of gelatin followed by extraction. However, these methods may result in the production of many byproducts[1].
N-Acetyl-L-proline Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
DONBOO AMINO ACID COMPANY | +8613063595538 | donboo@donboo.com | China | 9365 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 2990 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20293 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
View Lastest Price from N-Acetyl-L-proline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | N-Acetyl-L-proline
68-95-1
|
US $1.00 / g | 100g | 98% | 200kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-06-03 | N-Acetyl-L-proline
68-95-1
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Kingfiner Technology Development Co.Ltd | ||
2024-01-02 | N-acetyl-L-proline
68-95-1
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
- N-Acetyl-L-proline
68-95-1
- US $1.00 / g
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
- N-Acetyl-L-proline
68-95-1
- US $0.00-0.00 / kg
- 0.99
- Hebei Kingfiner Technology Development Co.Ltd
- N-acetyl-L-proline
68-95-1
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
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