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12(S)-HETE

12(S)-HETE
12(S)-HETE structure
CAS No.
54397-83-0
Chemical Name:
12(S)-HETE
Synonyms
12(S)-HETE;(s)-12-hete;12(S)-HETE MaxSpecStandard;12(S)-HETE Lipid Maps MS Standard;(S)-12-Hydroxyeicosatetraenoic acid;12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid;12(S)-HYDROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;12(S)-hydroxy-(5Z,8Z,10E,14Z)-*eicosatetraenoic A;(12S,5Z,8Z,10E,14Z)-12-Hydroxyeicosatetraenoic acid;12(S)-HYDROXY-(5Z,8Z,10E,14Z)-EICOSATETRAENOIC ACID
CBNumber:
CB0483829
Molecular Formula:
C20H32O3
Formula Weight:
320.47
MOL File:
54397-83-0.mol

12(S)-HETE Properties

Flash point:
14 °C
storage temp. 
−20°C
BRN 
2656104
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  7-16-26-36
RIDADR  UN 1170 3/PG 2
WGK Germany  1
8-10-23
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P235 Store in a well-ventilated place. Keep cool.

12(S)-HETE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H7768 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid ~100 μg/mL in ethanol, ≥95% (HPLC) 54397-83-0 10ug $247 2018-11-13 Buy
Cayman Chemical 34570 12(S)-HETE ≥98% 54397-83-0 25μg $99 2018-11-19 Buy
Cayman Chemical 10007248 12(S)-HETE MaxSpec? Standard ≥95% 54397-83-0 10μg $144 2018-11-19 Buy
Cayman Chemical 34570 12(S)-HETE ≥98% 54397-83-0 50μg $223 2018-11-19 Buy
Cayman Chemical 34570 12(S)-HETE ≥98% 54397-83-0 100μg $322 2018-11-19 Buy

12(S)-HETE Chemical Properties,Uses,Production

Uses

A fatty acid metabolite of arachidonic acid (A765000). Potential biomarker for asthma monitoring and diagnosis. Stimulates protein kinase C-mediated release of cathepsin B from malignant cells. Used in the study of mechanisms controlling cell cycle arrest and induction of apoptosis in prostate cancer cells via 12-lipoxygenase inhibition..

Definition

ChEBI: A HETE having a (12S)-hydroxy group and (5Z)-, (8Z)-, (10E)- and (14Z)-double bonds.

Uses

12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 μM.

12(S)-HETE Preparation Products And Raw materials

Raw materials

Preparation Products


12(S)-HETE Suppliers

Global( 17)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
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Chemsky (shanghai) International Co.,Ltd 021-50135380
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Sigma-Aldrich 021-61415566 800-819-3336(Tel) 400-620-3333(Mobile)
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885
021-65675885 info@efebio.com China 9976 58
Shenzhen Xinyaoxiong Industrial Co. Ltd. 0755-33204565 Sales QQ:2280077800(WeChat)
Advantage suppliers add cooperation QQ:577116998 szxys126@126.com China 54621 58

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