ChemicalBook >> CAS DataBase List >>Clobetasone butyrate
Clobetasone butyrate
- CAS No.
- 25122-57-0
- Chemical Name:
- Clobetasone butyrate
- Synonyms
- eumovate;Clobetasone-17-butyrate;sn203;Emovate;CCl 5537;molivate;GR 2/1214;Kindavate;(16-beta)-);17-Butyrate
- CBNumber:
- CB0497976
- Molecular Formula:
- C26H32ClFO5
- Molecular Weight:
- 478.98
- MDL Number:
- MFCD00133196
- MOL File:
- 25122-57-0.mol
- MSDS File:
- SDS
Last updated:2023-09-20 16:43:00
| Melting point | 90-100° |
|---|---|
| Boiling point | 573.3±50.0 °C(Predicted) |
| Density | 1.1736 (estimate) |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| solubility | Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent). |
| color | White to Off-White |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | FBRAWBYQGRLCEK-JGSYYNBSNA-N |
| SMILES | [C@]1(C(=O)CCl)(OC(=O)CCC)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C |&1:0,11,14,16,26,28,33,r| |
| CAS DataBase Reference | 25122-57-0(CAS DataBase Reference) |
| FDA UNII | 8U0H6XI6EO |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H351 | |||||||||
| Precautionary statements | P280 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 40 | |||||||||
| Safety Statements | 22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TU4154083 | |||||||||
| HS Code | 29372290 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983. | |||||||||
| NFPA 704 |
|
Clobetasone butyrate price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C5548 | Clobetasone butyrate ≥98% | 25122-57-0 | 100mg | $61.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | C2285000 | Clobetasone butyrate European Pharmacopoeia (EP) Reference Standard | 25122-57-0 | c2285000 | $153 | 2024-03-01 | Buy |
| TCI Chemical | C3510 | Clobetasone Butyrate >98.0%(HPLC) | 25122-57-0 | 50mg | $30 | 2024-03-01 | Buy |
| TCI Chemical | C3510 | Clobetasone Butyrate >98.0%(HPLC) | 25122-57-0 | 250mg | $194 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0001137 | Clobetasone butyrate for system suitability European Pharmacopoeia (EP) Reference Standard | 25122-57-0 | y0001137 | $150 | 2024-03-01 | Buy |
Clobetasone butyrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white powder.
Uses
Clobetasone butyrate is a synthetic glucocorticoid which is used as an anti-inflammatory in the treatment of various skin disorders. As a steroid medicine, it can used on the skin to treat swelling, itching and irritation. Such as eczema, including ;contact dermatitis; psoriasis; insect bites and stings; nappy rash.
Definition
ChEBI: Clobetasone butyrate is an organic molecular entity.
Mechanism of action
Topical corticosteroids (Clobetasone butyrate) inhibit the migration of macrophages and leukocytes into areas of inflamed skin by reversing vascular dilation and permeability, resulting in decreased erythema, edema and pruritus.
Side effects
Some people get a burning or stinging feeling for a few minutes when they put clobetasone cream or ointment on their skin. Clobetasone cream contains cetostearyl alcohol and chlorocresol, which may cause local skin reactions or allergic reactions.
Clobetasone butyrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 165)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 968 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
View Lastest Price from Clobetasone butyrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | Clobetasone butyrate
25122-57-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-08-22 | Clobetasone butyrate
25122-57-0
|
US $25.00 / kg | 1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd | |
 |
2023-07-20 | Clobetasone butyrate
25122-57-0
|
US $100.00 / kg | 1kg | 99% | 1000tons | Henan Bao Enluo International TradeCo.，LTD |
-
- Clobetasone butyrate
25122-57-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Clobetasone butyrate
25122-57-0
- US $25.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd
-
- Clobetasone butyrate
25122-57-0
- US $100.00 / kg
- 99%
- Henan Bao Enluo International TradeCo.，LTD
25122-57-0(Clobetasone butyrate)Related Search:
(16-beta)-)
11,20-trione,21-chloro-9-fluoro-17-hydroxy-16-beta-methyl-pregna-4-diene-3
21-chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione
molivate
pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy
sn203
21-chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
ClobetasolPropionate-Bp/Ep/Usp
Butyric acid, ester with 21-chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione (8CI)
CCl 5537
Emovate
GR 2/1214
Kindavate
Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16β)-
Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16β-methyl-, butyrate (8CI)
21-Chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione 17-butyrate
Clobetasone butyrate
CLOBETASOLE BUTYRATE
21-Chloro-9-fluoro-16β-methyl-17-(1-oxobutoxy)pregna-1,4-diene-3,11,20-trione
21-Chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione=butyrate
[(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
[(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroethanoyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
butyric acid [(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-3,11-diketo-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] ester
17-Butyrate
)-pregn-5-en-20-one
3,17-Dihydroxy-16-methyl-(3&beta
)-3,17-Dihydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methyl|piperidinium Bromide
)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
)-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide-d3
-Hydroxytestosterone
)-11-Hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione
)-17-Acetyloxy-3-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide
)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione
20R)-9-Fluoro-11,20-dihydroxy-16-methyl-3-oxopregna-1,4-dien-21-oic Acid|(Betamethasone Impurity)
)-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide
-Hydroxy Stanozolol
H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione|(Deflazacort Impurity)
)-9-Fluoro-11,17,21-trihydroxy-16-methylpregn-4-ene-3,20-dione
)-17,21-Bis(acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione
-Hydroxy-17-epi-norethisterone
H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione
-Hydroxymestanolone
)-6-Bromo-9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxopentyl)oxy]-pregna-1,4-diene-3,20-dione
Clonazepam impurity B CRS
Clobetasone butyrate for system suitability CRS
Clobetasone butyrate CRS
Clobetasone butyrate solution in Acetonitrile，100μg/mL
Clobetasone ButyrateQ: What is
Clobetasone Butyrate Q: What is the CAS Number of
Clobetasone Butyrate Q: What is the storage condition of
Clobetasone Butyrate
4-(methylamino)-3-nitro-
eumovate
Clobetasone-17-butyrate
21-chloro-9-fluoro-16β-methyl-3,11,20-trioxopregna-1,4-dien-17-ylbutanoate
Simvastatin Impurity 44
25122-57-0
C26H32ClFO5
Intermediates & Fine Chemicals
Pharmaceuticals
Steroids