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Cyclicdimethylpolysiloxane

CAS No.
69430-24-6
Chemical Name:
Cyclicdimethylpolysiloxane
Synonyms
POLYDIMETHYLCYCLOSILOXANE;kf993;UP 1004;q2-1401;sws-f222;sws03314;X 2-1401;dowcorning344;Silwet FZ 2166;Silicone TSA 405A
CBNumber:
CB0500393
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD01771102
MOL File:
Mol file
Last updated:2023-05-04 15:14:08

Cyclicdimethylpolysiloxane Properties

FDA UNII NMQ347994Z
EPA Substance Registry System Cyclomethicone (69430-24-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS02
Signal word  Warning
Hazard statements  H413-H361-H412-H226
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P273-P501
RIDADR  1993
HazardClass  3.2
PackingGroup  III

Cyclicdimethylpolysiloxane Chemical Properties,Uses,Production

Chemical Properties

Cyclomethicone occurs as a clear, colorless and tasteless volatile liquid.

Uses

Pharmaceutic aid (wetting agent).

Production Methods

Cyclomethicone is manufactured by the distillation of crude polydimethylsiloxanes.

brand name

VS-7158 (Witco); VS-7207 (Witco); VS-7349 (Witco).

Pharmaceutical Applications

Cyclomethicone is mainly used in topical pharmaceutical and cosmetic formulations such as water-in-oil creams.
Cyclomethicone has been used in cosmetic formulations, at concentrations of 0.1-50%, since the late 1970s and is now the most widely used silicone in the cosmetics industry. Its high volatility, and mild solvent properties, make it ideal for use in topical formulations because its low heat of vaporization means that when applied to skin it has a ‘dry’ feel.

Safety

Cyclomethicone is generally regarded as a relatively nontoxic and nonirritant material. Although it has been used in oral pharmaceutical applications, cyclomethicone is mainly used in topical pharmaceutical formulations. It is also widely used in cosmetics. Studies of the animal and human toxicology of cyclomethicone suggest that it is nonirritant and not absorbed through the skin. Only small amounts are absorbed orally; an acute oral dose in rats produced no deaths.

storage

Cyclomethicone should be stored in an airtight container in a cool, dry, place.

Regulatory Status

Included in the FDA Inactive Ingredients Database(oral powderfor reconstitution, topical lotion, topical cream, topical emulsion). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Cyclicdimethylpolysiloxane Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd
510-85010237 overseamarketing@alphahi-tech.com CHINA 41 58
Hangzhou Bayee Chemical Co., Ltd.
0086-571-86990109 rachelhoo@bayeechem.com China 104 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9353 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8822 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213 info@longyupharma.com China 2531 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
BEYOND INDUSTRIES (CHINA) LIMITED
+86-21-52699951; +8613917686115 sales@beyondindustriesgroup.com China 699 58

View Lastest Price from Cyclicdimethylpolysiloxane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cyclomethicone pictures 2024-04-16 Cyclomethicone
69430-24-6
US $70.00 / KG 1000KG 99 10000 kilograms/ month Hebei Yime New Material Technology Co., Ltd.
Cyclodimethylsiloxanes pictures 2023-03-06 Cyclodimethylsiloxanes
69430-24-6
US $10.70 / Kg/Drum 10g 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
Cyclicdimethylpolysiloxane pictures 2022-09-01 Cyclicdimethylpolysiloxane
69430-24-6
US $50.00 / kg 1kg 99% 1 Hebei Duling International Trade Co. LTD
  • Cyclomethicone pictures
  • Cyclomethicone
    69430-24-6
  • US $70.00 / KG
  • 99
  • Hebei Yime New Material Technology Co., Ltd.
sws03314 sws-f222 Cyclomethicone 6 (200 mg) Cyclodimethylsiloxanes Silicone TSA 405A Siloxanes, cyclic, di-Me Silwet FZ 2166 UP 1004 X 2-1401 cyclosiloxanes,di-me dimethylcyclopolysiloxane dowcorning344 CYCLOMETHICONE 4 (200 MG) Cyclicdimethylpolysiloxane cyclopolydimethylsiloxane q2-1401 dowcorning344fluid dowcorningx2-1401 kf993 polydimethylsiloxycyclics DMC Cyclodimethylsiloxanes Cyclomethicone (pharmaceutical grade) POLYDIMETHYLCYCLOSILOXANE Dimethyl siloxane cyclics mixture Cyclic polydimethylsiloxane 69430-24-6 UVCBs-organic J's