ChemicalBook >> CAS DataBase List >>2-Bromo-5-chlorobenzaldehyde

2-Bromo-5-chlorobenzaldehyde

CAS No.
174265-12-4
Chemical Name:
2-Bromo-5-chlorobenzaldehyde
Synonyms
2-Bromo-5 chloraldehyde;2-Bromo-5-chlorobenzalde;2-Bromo-5-chlorobenzaldehyde;5-Chloro-2-bromobenzaldehyde;Benzaldehyde,2-bromo-5-chloro-;2-Bromo-5-chlorobenzaldehyde >
CBNumber:
CB0500924
Molecular Formula:
C7H4BrClO
Molecular Weight:
219.46
MDL Number:
MFCD00462870
MOL File:
174265-12-4.mol
MSDS File:
SDS
Last updated:2025-08-13 11:09:07
Product description Number Pack Size Price
2-Bromo-5-chlorobenzaldehyde >97.0%(GC) B2955 5g $28
2-Bromo-5-chlorobenzaldehyde >97.0%(GC) B2955 25g $111
2-Bromo-5-chlorobenzaldehyde B699438 10mg $45
2-Bromo-5-chlorobenzaldehyde FB33572 10g $50
2-Bromo-5-chlorobenzaldehyde FB33572 25g $80
More product size

2-Bromo-5-chlorobenzaldehyde Properties

Melting point 66 °C
Boiling point 258 °C
Density 1.698
Flash point 110 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form Crystalline
color Pale yellow
InChI InChI=1S/C7H4BrClO/c8-7-2-1-6(9)3-5(7)4-10/h1-4H
InChIKey IIISHLMCTDMUHH-UHFFFAOYSA-N
SMILES C(=O)C1=CC(Cl)=CC=C1Br
CAS DataBase Reference 174265-12-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H335-H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  22
Safety Statements  24/25
RIDADR  UN1993
HS Code  29130000
NFPA 704
1
2 0

2-Bromo-5-chlorobenzaldehyde price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B2955 2-Bromo-5-chlorobenzaldehyde >97.0%(GC) 174265-12-4 5g $28 2025-07-31 Buy
TCI Chemical B2955 2-Bromo-5-chlorobenzaldehyde >97.0%(GC) 174265-12-4 25g $111 2025-07-31 Buy
TRC B699438 2-Bromo-5-chlorobenzaldehyde 174265-12-4 10mg $45 2021-12-16 Buy
Biosynth Carbosynth FB33572 2-Bromo-5-chlorobenzaldehyde 174265-12-4 10g $50 2021-12-16 Buy
Biosynth Carbosynth FB33572 2-Bromo-5-chlorobenzaldehyde 174265-12-4 25g $80 2021-12-16 Buy
Product number Packaging Price Buy
B2955 5g $28 Buy
B2955 25g $111 Buy
B699438 10mg $45 Buy
FB33572 10g $50 Buy
FB33572 25g $80 Buy

2-Bromo-5-chlorobenzaldehyde Chemical Properties,Uses,Production

Uses

2-Bromo-5-chlorobenzaldehyde is an important class of pharmaceutical intermediates which can be used in the synthesis of a variety of drugs. 2-Bromo-5-chlorobenzaldehyde can be used in the preparation of the compound 3-chloro-14-cyclohexyl-6-[2-(dimethylamino)ethyl]-7-oxo-5,6,7,8-tetrahydroindolo[2,1-a][2,5]benzo[di-acridine]-11-carboxylic acid, which can be used in the treatment or prevention of viral infections.

Synthesis

2-Bromo-1-bromomethyl-5-chlorobenzene

66192-24-3

2-Bromo-5-chlorobenzaldehyde

174265-12-4

Step 2: Synthesis of 2-bromo-5-chlorobenzaldehyde; Preparation was carried out with reference to the literature method (J. Am. Chem. Soc. 2002, 124(7), 1354): a mixture of activated powdered 4A molecular sieves (800 mg/mmol of substrate), N-methylmorpholine-N-oxide (2 eq.) and 2-bromomethyl-5-chlorobenzaldehyde (1 eq.) was stirred for 2 hours at 0°C in a N -methylpyrrolidone (0.16 M) were stirred for 2 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad and the filtrate was subsequently concentrated under vacuum to afford the target product 2-bromo-5-chlorobenzaldehyde in 92% yield.

References

[1] Patent: WO2006/46030, 2006, A2. Location in patent: Page/Page column 28
[2] Journal of the American Chemical Society, 2002, vol. 124, # 7, p. 1354 - 1363

66192-24-3
174265-12-4
Synthesis of 2-Bromo-5-chlorobenzaldehyde from 2-Bromo-1-bromomethyl-5-chlorobenzene
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View Lastest Price from 2-Bromo-5-chlorobenzaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-chlorobenzaldehyde pictures 2026-01-05 2-Bromo-5-chlorobenzaldehyde
174265-12-4
US $1.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Bromo-5-chlorobenzaldehyde pictures 2026-01-05 2-Bromo-5-chlorobenzaldehyde
174265-12-4
US $0.00-0.00 / KG 10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2-Bromo-5-chlorobenzaldehyde pictures 2022-01-15 2-Bromo-5-chlorobenzaldehyde
174265-12-4
US $0.00 / KG 1KG 97.1% 100 tons Honest Joy Holdings Limited
5-Chloro-2-bromobenzaldehyde 2-Bromo-5-chlorobenzaldehyde 2-Bromo-5-chlorobenzalde Benzaldehyde,2-bromo-5-chloro- 2-Bromo-5-chlorobenzaldehyde > 2-Bromo-5 chloraldehyde 174265-12-4 84459-33-7 Chlorine Compounds Adehydes, Acetals & Ketones Bromine Compounds