Iotalamic acid
- CAS No.
- 2276-90-6
- Chemical Name:
- Iotalamic acid
- Synonyms
- MI-216;Iothalamic;Metalamic acid;iothalamicacid;iotalamic acid;IOTHALAMIC ACID (200 MG);Iotalamic acid USP/EP/BP;5-acetamido-2,4,6-triiodo-N-methylisophthalamic acid;3-Acetylamino-5-methylcarbamoyl-2,4,6-triiodobenzoic acid;3-Acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
- CBNumber:
- CB0501411
- Molecular Formula:
- C11H9I3N2O4
- Molecular Weight:
- 613.91
- MDL Number:
- MFCD00800738
- MOL File:
- 2276-90-6.mol
- MSDS File:
- SDS
| Melting point | >300 °C (decomp) |
|---|---|
| Boiling point | 520.2±50.0 °C(Predicted) |
| Density | 2.4079 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
| form | Solid |
| pka | 0.78±0.10(Predicted) |
| color | Off-White to Pale Yellow |
| CAS DataBase Reference | 2276-90-6(CAS DataBase Reference) |
| FDA UNII | 16CHD79MIX |
| ATC code | V08AA04 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
| HS Code | 2924296000 |
| Toxicity | man,TDLo,unreported,2143uL/kg (2.143mL/kg),SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYELUNGS, THORAX, OR RESPIRATION: DYSPNEA,AJR, American Journal of Roentgenology. Vol. 162, Pg. 997, 1994. |
Iotalamic acid price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1345002 | Iotalamic acid United States Pharmacopeia (USP) Reference Standard | 2276-90-6 | 200MG | $106.8 | 2024-03-01 | Buy |
| TRC | I736200 | IothalamicAcid | 2276-90-6 | 5mg | $205 | 2021-12-16 | Buy |
| Usbiological | 164509 | Iothalamic Acid | 2276-90-6 | 5mg | $496 | 2021-12-16 | Buy |
| Crysdot | CD12094017 | Iotalamicacid 98+% | 2276-90-6 | 10mg | $194 | 2021-12-16 | Buy |
| Crysdot | CD12094017 | Iotalamicacid 98+% | 2276-90-6 | 5mg | $104 | 2021-12-16 | Buy |
Iotalamic acid Chemical Properties,Uses,Production
Chemical Properties
Off-white Solid
Originator
Conray,Mallinckrodt Inc.,US,1962
Uses
Iothalamic Acid is used as a contrast medium in diagnostic radiology. Iothalamic Acid displayed the same level of nephrotoxicity against rat and human renal epithelial cells as conventional ionic contrast medioum.
Uses
Iothalamic Acid is used as a contrast medium in diagnostic radiology. Iothalamic Acid displayed the same level of nephrotoxicity against rat and human renal epithelial cells as conventional ionic cont rast medioum.
Definition
ChEBI: Iotalamic acid is an organic molecular entity.
Manufacturing Process
Crude 5-amino-2,4,6-triiodo-N-methylisophthalamic acid (21.0 g) was
dissolved in warm dimethylacetamide (40 ml) and acetic anhydride (30 ml)
and concentrated sulfuric acid (2 drops) were added. This solution was heated
on the steam bath for 2 hours, then heated at 110°C for 5 minutes, then
cooled. Water and ammonium hydroxide were added to destroy the excess
acetic anhydride, after which the mixture was evaporated to a volume of 50
ml. The cooled solution was acidified with concentrated hydrochloric acid and
a tan solid was collected. The crude product was dissolved in 100 ml of water
containing a slight excess of sodium hydroxide. The pH was adjusted to 4.5
with acetic acid, and the solution was treated with charcoal. The colorless
solution was acidified with concentrated hydrochloric acid and cooled, and the
precipitate was filtered off and dried under reduced pressure. The resulting 5-
acetamido-2,4,6-triiodo-N-methylisophthalamic acid decomposes about 285°C
and does not melt below 300°C.
5-acetamido-2,4,6-triiodo-N-methylisophthalamic acid was slurried in water
and dissolved by the addition of an equivalent quantity of N-methylglucamine.
The solution was evaporated to dryness to yield the meglumate salt of 5-
acetamido-2,4,6-triiodo-N-methylisophthalamic acid.
brand name
Conray(Mallinckrodt).
Therapeutic Function
Diagnostic aid (radiopaque medium)
Iotalamic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9409 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18457 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 | chemwill_asia@126.com | CHINA | 23931 | 58 |
View Lastest Price from Iotalamic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | Iotalamic acid
2276-90-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-08-08 | Iotalamic acid
2276-90-6
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Iotalamic acid
2276-90-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Iotalamic acid
2276-90-6
- US $7.00 / KG
- 99%
- Career Henan Chemical Co