Diethylstilbestrol
- CAS No.
- 6898-97-1
- Chemical Name:
- Diethylstilbestrol
- Synonyms
- DES;Diethylstilbestrol;Diethylstillbestrol;3,4-Bis(4-hydroxypheny;Diethylstilbestrol >(E,Z)-Diethylstilbestrol;Diethylstilbestrol-(E,Z);Atovaquone CAS NO.6898-97-1;Diethylstilbestrol USP/EP/BP;4,4'-Hex-3-ene-3,4-diyldiphenol
- CBNumber:
- CB0503501
- Molecular Formula:
- C18H20O2
- Molecular Weight:
- 268.35
- MDL Number:
- MFCD00002373
- MOL File:
- 6898-97-1.mol
| Melting point | 170-172 °C(lit.) |
|---|---|
| Boiling point | 407.1±25.0 °C(Predicted) |
| Density | 1.107±0.06 g/cm3(Predicted) |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 9.27±0.15(Predicted) |
| color | White to Almost white |
| Merck | 14,3129 |
| InChIKey | RGLYKWWBQGJZGM-ISLYRVAYSA-N |
| CAS DataBase Reference | 6898-97-1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335-H350-H360FD-H410 | |||||||||
| Precautionary statements | P202-P261-P273-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 45-61-36/37/38-51/53 | |||||||||
| Safety Statements | 53-36/37/39-45-60-61 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WJ5600000 | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29072990 | |||||||||
| NFPA 704 |
|
Diethylstilbestrol price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 218944 | Diethylstilbestrol, mixture of cis and trans 97% | 6898-97-1 | 5g | $113 | 2023-06-20 | Buy |
| TCI Chemical | D0526 | Diethylstilbestrol >98.0%(GC) | 6898-97-1 | 1g | $48 | 2024-03-01 | Buy |
| TCI Chemical | D0526 | Diethylstilbestrol >98.0%(GC) | 6898-97-1 | 5g | $119 | 2024-03-01 | Buy |
| Usbiological | 446134 | Des- | 6898-97-1 | 10mg | $460 | 2021-12-16 | Buy |
| Usbiological | 446129 | Des- | 6898-97-1 | 2.5mg | $460 | 2021-12-16 | Buy |
Diethylstilbestrol Chemical Properties,Uses,Production
Description
Diethylstilbestrol is a derivative of stilbene, and it differs from sin-estrol by the presence of a double bond with trans-configuration of the two phenyl groups. In terms of estrogenic activity, this drug surpasses both estrone and hexestrol.
Chemical Properties
White solid
Uses
Diethylstilbestrol was used as internal standard for the analysis of drug residues in urine of rats and calves by on-line HPLC with ultraviolet and continuous-flow fast atom bombardmentmass spectrometry detectors.
Definition
ChEBI: Diethylstilbestrol is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. It has a role as an antineoplastic agent, a carcinogenic agent, a xenoestrogen, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an antifungal agent, an endocrine disruptor, an EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor, an autophagy inducer and a calcium channel blocker. It is a polyphenol and an olefinic compound.
General Description
Mechanisms of the isomerization processes of molecular and anionic diethylstilbestrol (DES) has been reported. Estrogen activity of cis- and trans-diethylstilbestrol has been evaluated. Diethylstilbestrol is a carcinogenic synthetic estrogen.
Synthesis
Diethylstilbestrol, trans-|á,|?-diethyl-4,4-stilbendiol (28.1.34), is proposed to be synthesized in various ways. According to one of them, desoxyansoine is alkylated by ethyl iodide in the presence of sodium ethoxide, and the resulting ketone (28.1.30) is reacted in a Grignard reaction with ethylmagnesium bromide, which forms the carbinol (28.1.31). Dehydration of this compound by distillation in the presence of p-toluenesulfonic acid gives dimethyl ether of stilbestrol (28.1.32), methyl groups of which are removed by heating it at high temperatures with potassium hydroxide, thus forming diethylstilbestrol (28.1.33).
Diethylstilbestrol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | +8615377521700 | wangwendy93@gmail.com | China | 868 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9409 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9427 | 58 |
| Wuhan Godbullraw Chemical Co.,ltd | +undefined18986288449 | Alisasales@godbullraw.com | China | 560 | 58 |
View Lastest Price from Diethylstilbestrol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-17 | Diethylstilbestrol
6898-97-1
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-04-01 | Diethylstilbestrol
6898-97-1
|
US $0.00-0.00 / KG | 1KG | 99% | 500 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2024-03-16 | Diethylstilbestrol
6898-97-1
|
US $0.00 / KG | 100g | 98%+ | 100kg | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD |
-
- Diethylstilbestrol
6898-97-1
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- Diethylstilbestrol
6898-97-1
- US $0.00-0.00 / KG
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Diethylstilbestrol
6898-97-1
- US $0.00 / KG
- 98%+
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
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