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PERK-IN-2

PERK-IN-2 Structure
PERK-IN-2 structure
CAS No.
1337531-83-5
Chemical Name:
PERK-IN-2
Synonyms
PERK-IN-2;PERKIN2,PERK IN 2;7-methyl-5-{1-[(2,3,5-trifluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine;Ethanone, 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-(2,3,5-trifluorophenyl)-
CBNumber:
CB05821277
Molecular Formula:
C23H18F3N5O
Molecular Weight:
437.42
MDL Number:
MFCD34469700
MOL File:
1337531-83-5.mol
Last updated:2025-04-18 09:51:30
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PERK-IN-2 Properties

Boiling point 726.8±60.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
pka 5.76±0.30(Predicted)
form Solid
color Off-white to light brown

PERK-IN-2 Chemical Properties,Uses,Production

Uses

PERK-IN-2 is a potent PERK inhibitor with an IC50 of 0.2 nM[1].

References

[1] Axten JM , et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem. 2012 Aug 23;55(16):7193-207. DOI:10.1021/jm300713s

PERK-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

PERK-IN-2 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32281 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38665 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10523 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20622 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
cjbscvictory 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58

View Lastest Price from PERK-IN-2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PERK-IN-2 pictures 2024-10-28 PERK-IN-2
1337531-83-5
 US $92.00 / mg 10g TargetMol Chemicals Inc.
  • PERK-IN-2 pictures
  • PERK-IN-2
    1337531-83-5
  • US $92.00 / mg
  • TargetMol Chemicals Inc.
PERK-IN-2 7-methyl-5-{1-[(2,3,5-trifluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine Ethanone, 1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-(2,3,5-trifluorophenyl)- PERKIN2,PERK IN 2 1337531-83-5