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Lipase

Description References
Lipase
Lipase structure
CAS No.
9001-62-1
Chemical Name:
Lipase
Synonyms
pase;n-ap;ipase;Lipase;lipazin;tweenase;meitomy30;LIPASE AS;LIPASE AK;LIPASE PS
CBNumber:
CB0664101
Molecular Formula:
C11H9N3NaO2+
Formula Weight:
238.19783
MOL File:
9001-62-1.mol

Lipase Properties

Density 
1.2
storage temp. 
2-8°C
solubility 
H2O: 2 mg/mL, hazy with insoluble particles, faintly yellow
form 
solution
color 
yellow-brown
Water Solubility 
It is soluble in water.
Merck 
13,5533
Stability:
Moisture sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference
9001-62-1
FDA 21 CFR
184.1415; 310.545
Substances Added to Food (formerly EAFUS)
LIPASE
EWG's Food Scores
1
NCI Drug Dictionary
pancrelipase
EPA Substance Registry System
Lipase, triacylglycerol (9001-62-1)
SAFETY
  • Risk and Safety Statements
Hazard Codes  B,Xn
Risk Statements  20/21/22
Safety Statements  22-24/25-36/37-36
WGK Germany  3
RTECS  TO9776500
3-10-21
TSCA  Yes
HS Code  35079020

Lipase price More Price(96)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 62310 Lipase from Rhizopus niveus powder(fine),≥1.5?U/mg 9001-62-1 10 g $50.9 2021-12-16 Buy
Sigma-Aldrich 62310 Lipase from Rhizopus niveus powder(fine),≥1.5?U/mg 9001-62-1 50 g $182 2021-12-16 Buy
Sigma-Aldrich L0382 Lipase from porcine pancreas Type VI-S, ≥20,000?units/mg protein, lyophilized powder 9001-62-1 100000 units $237 2021-12-16 Buy
Sigma-Aldrich 62287 Lipase A Candida antarctica, recombinant from Aspergillus oryzae powder, beige, ~2?U/mg 9001-62-1 50 mg $100 2021-12-16 Buy
Sigma-Aldrich 534730 Amano Lipase from Pseudomonas fluorescens beige-brown, ≥20,000 U/g 9001-62-1 50g $126 2021-12-16 Buy

Lipase Chemical Properties,Uses,Production

Description

Lipase is an enzyme and belongs to the class of hydrolase. Lipase is produced in the pancreas, mouth, and stomach.  It catalyzes the hydrolysis of triglycerides to glycerol and free fatty acids. The body uses lipase to break down fats in food so they can be absorbed in the intestines.
Lipases are widely employed to catalyze hydrolysis, alcoholysis, esterification, interesterification, acidolysis and transesterification of carboxylic esters. Their unique characteristics include substrate specificity, stereospecificity, regioselectivity and ability to catalyze a heterogeneous reaction at the interface of water soluble and water insoluble systems. Lipases are used as flavor and aroma constituents in the food industry, to produce valuable oleo chemical species for diesel engines,  as additives in cosmetic formulations, to remove the pitch from pulp produced in the paper industry, for the hydrolysis of milk fat in the dairy industry, to remove non-cellulosic impurities from raw cotton before further processing into dyed and finished products, for the drug formulations in the pharmaceutical industry, and to remove subcutaneous fat in the leather industry. Lipases are also used to diagnose pancreatitis in patients. Clinically lipases help a person who has cystic fibrosis, Alzheimer's disease, atherosclerosis and act as a candidate target for cancer prevention and therapy. Lipases are also used to treat obesity in recent years.

References

[1] http://www.umm.edu/health/medical/altmed/supplement/lipase
[2] Tianwei Tan, Jike Lu, Kaili Nie, Li Deng, Fang Wang (2010) Biodiesel production with immobilized lipase: A reveiw, 28, 628-634
[3] G. D. Haki, S. K. Rakshit (2003) Developments in industrially important thermostable enzymes: a rview, 89, 17-34
[4] Jack M. Goldberg (1976) Diagnostic use of pancreatic lipase determination by radial enzyme diffusion, and design of a routine pancreatic profile, 22, 638-642
[5] H. Loli, SK. Narwal, NK. Saun, R. Gupta (2015) Lipases in medicine: an overview, 15, 1209-1216

Description

Lipase is obtained from two primary sources: (1) the edible fore stomach tissue of calves, kids, or lambs and; (2 ) animal pancreatic tissue. It is produced as purified edible tissue preparations or as aqueous extracts. It is dispersible in water and insoluble in alcohol. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Description

Produced by the controlled fermentation of Aspergillus niger var. as an off-white to tan amorphous powder. Soluble in water (the solution is usually light yellow), but practically insoluble in alco hol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Description

Produced by the controlled fermentation of Aspergillus oryzae var. as an off-white to tan amorphous powder or a liquid. Soluble in water (the solution is usually light yellow), but practically insol uble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Description

Produced by the controlled fermentation of Candida rugosa as an off-white to tan powder. Soluble in water but practically insoluble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.

Chemical Properties

powder

Uses

To split fats without damaging sensitive constituents, such as vitamins or unsaturated fatty acids. In food processing for flavor improvement; in detergents for the improvement of cleaning action. For review of industrial applications of microbial lipases, see Seitz, J. Am. Oil Chem. Soc. 51, 12 (1974).

Uses

Trans fatty acids (TFAs) are fatty acids with at least one double bond in (E)- configuration. The consumption of TFAs increases the risk of coronary heart diseases. Thus, their concentrations in lipid-containing products should be reduced [87]. Naturally, TFAs occur in small amounts in meat and milk of ruminants, but the most significant concentrations of TFAs develop during partial hydrogenation and deodorization of fats [88]. The formation of TFAs during fat hardening can be avoided by lipase catalyzed transesterification to increase the slip melting points of fats.
For enzymatic transesterification between different lipids, triacylglycerol lipases (triacylglycerol acylhydrolase, EC 3.1.1.3) acting on the SN1 and SN3 positions of the triglyceride are used. Various lipases have been applied for the production of table margarine out of fat-oil blends. Lipases of the ascomycetes Thermomyces lanuginosa and Rhizomucor miehei, as well as a lipase of the proteobacterium Pseudomonas sp., were used for transesterification of fat blends consisting of palm stearin and vegetable oil. Fully hydrogenated oils in blends with vegetable oils also have been used. In all studies, an increase of the slip melting points and the solid fat content was achieved in the fat-oil blend, thus indicating an alternative method for fat hardening via hydrogenation.

Uses

Lipase, is used as a catalyst in the preparation of biodiesels?and in the preparation of esters of chiral epoxy alcohols.?Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.

Definition

lipase: An enzyme secreted by thepancreas and the glands of the smallintestine of vertebrates that catalysesthe breakdown of fats into fatty acidsand glycerol.

General Description

Pancrelipase (Cotazym) has agreater lipolytic action than other pancreatic enzyme preparations.Hence, it is used to help control steatorrhea and inother conditions in which pancreatic insufficiency impairsthe digestion of fats in the diet.

Biochem/physiol Actions

Amano lipase M is capable of catalyzing Michael addition of pyrimidine with disaccharide acrylates in organic media.

Lipase Preparation Products And Raw materials

Raw materials

Preparation Products


Lipase Suppliers

Global( 279)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Qingdao kaimoshi biochemical technology co., ltd.
+(86) 571 87700752
+(86) 571 87700752 info@kaimosi.com CHINA 145 58
Henan DaKen Chemical CO.,LTD.
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Henan Tianfu Chemical Co.,Ltd.
0371-55170693
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Tianjin Zhongxin Chemtech Co., Ltd.
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career henan chemical co
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Hubei Jusheng Technology Co.,Ltd.
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Shandong chuangyingchemical Co., Ltd.
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sale@chuangyingchem.com CHINA 5917 58
Chongqing Chemdad Co., Ltd
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View Lastest Price from Lipase manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-01 Lipase
9001-62-1
US $9.00 / ASSAYS 1ASSAYS 99% 10000kg Hebei Crovell Biotech Co Ltd
2021-11-15 Lipase
9001-62-1
US $70.00 / KG 1KG 99% 100kg/Month Hebei Yirun Sega Biological Technology Co. Ltd
2021-10-16 Lipase
9001-62-1
US $10.00 / KG 1KG 99% 20 tons Hebei Zhanyao Biotechnology Co. Ltd

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