ChemicalBook >> CAS DataBase List >>2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE structure

CAS No.: 60762-57-4

Chemical Name:: 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE

Synonyms: Pirlindol;Pyrazidol;Pirlindole;Pirlindolum;Unii-V39yph45fz;PIRLINDOLE MESYLATE;Pirlindole free base;Ombitasvir Impurity 6;Pirlindolum [inn-latin];16154-78-2 (Hydrochloride)

CBNumber:: CB0671512

Molecular Formula:: C15H18N2

Molecular Weight:: 226.32

MDL Number:: MFCD00407230

MOL File:: 60762-57-4.mol

Last updated:2023-05-18 11:31:06

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2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Properties

storage temp.	Store at RT
solubility	DMF: 1 mg/ml; DMSO: 5 mg/ml
form	A crystalline solid
FDA UNII	V39YPH45FZ

SAFETY

Risk and Safety Statements

HazardClass	IRRITANT

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	22060	Pirlindole ≥98%	60762-57-4	5mg	$71	2024-03-01	Buy
Cayman Chemical	22060	Pirlindole ≥98%	60762-57-4	10mg	$133	2024-03-01	Buy
Cayman Chemical	22060	Pirlindole ≥98%	60762-57-4	25mg	$313	2024-03-01	Buy
Cayman Chemical	22060	Pirlindole ≥98%	60762-57-4	50mg	$590	2024-03-01	Buy
Tocris	0724	Pirlindolemesylate	60762-57-4	50	$628	2021-12-16	Buy

Product number	Packaging	Price	Buy
22060	5mg	$71	Buy
22060	10mg	$133	Buy
22060	25mg	$313	Buy
22060	50mg	$590	Buy
0724	50	$628	Buy

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Chemical Properties,Uses,Production

Description

Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC₅₀s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (K_is = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC₅₀ value of 7.7 μM independent of MAO-A activity.

Uses

Antidepressive;Monoamine oxidase inhibitor

Biological Activity

A highly selective reversible inhibitor of monoamine oxidase type A.

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE Suppliers

Global( 35)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 18112977050	cb6@aikonchem.com	China	16687	50
Tcichem, Inc.	13918644899	tianchong009@hotmail.com	China	1756	55

Supplier	Advantage
Nanjing Finetech Chemical Co., Ltd.	55
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
BOC Sciences	65
Shanghai TaoSu Biochemical Technology Co., Ltd.	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	50
Tcichem, Inc.	55

60762-57-4(2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE)Related Search:

1,10-Trimethylene-2-butyl-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-a)in dole hydrochloride 1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-3-prop yl-, hydrochloride 10-CYCLOHEXYL-1,2,3,3A,4,5-HEXAHYDRO-6H-PYRAZINO[1,2,3-L,M]CARBAZOLE 3-BENZYL-2,3,3A,4,5,6-HEXAHYDRO-1H-PYRAZINO[3,2,1-JK]CARBAZOLE-8-CARBALDEHYDE 2-CHLORO-1-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO[3,2,1-JK]CARBAZOL-3-YL)-ETHANONE

2,3,3A,4,5,6-HEXAHYDRO-8-CYCLOHEXYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 3-(8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-PYRAZINO-[3,2,1-JK]CARBAZOL-3-YL)PROPIONIC ACID 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 8-METHYL-1,2,3A,4,5,6-HEXAHYDRO-3H-PYRAZINO[3,2,1-JK]CARBAZOLE-3-CARBALDEHYDE

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PIRLINDOLE MESYLATE 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole 16154-78-2 (Hydrochloride) Pirlindol Pirlindol [inn-spanish, french] Pirlindolum Pirlindolum [inn-latin] Unii-V39yph45fz Pirlindole 2,3,3A,4,5,6-HEXAHYDRO-8-METHYL-1H-PYRAZINO[3,2,1-J,K]CARBAZOLE MESYLATE 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole methanesulfonate 1H-Pyrazino[3,2,1-jk]carbazole,2,3,3a,4,5,6-hexahydro-8-methyl- Pirlindole free base Pyrazidol Ombitasvir Impurity 6 60762-57-4 C15H18N2CH3SO3H Monoamine Oxidase